The Impact of Passive Heat Treatment on Glycaemic Response During an Oral Glucose Tolerance Test in Diabetic Patients (Sauna-OGTT)
Diabetes Mellitus, Type 2
About this trial
This is an interventional basic science trial for Diabetes Mellitus, Type 2
Eligibility Criteria
Inclusion Criteria: Aged ≥50 years old Body mass index 18.5 - 35 kg/m2 DM type 2 Using oral blood glucose lowering medication Able to give informed consent Exclusion Criteria: Insulin dependence Changes in diabetes medication in the past 3 months Allergy for one of the food items used >5% weight change in the previous 6 months Participating in a structured (progressive) exercise program, or in the past 3 months. Frequent (once per week or more) user of infrared (or traditional) sauna in the past 3 months Inability to tolerate sauna/high temperatures Smoking Diagnosed with cardiovascular disease (e.g. unstable angina pectoris or recent myocardial infarction), kidney failure (eGFR < 60 ml/min/1.73m2), rheumatoid arthritis Diagnosed musculoskeletal, GI tract, metabolic (except diabetes) or pulmonary (e.g. COPD) disorders that are expected to influence study outcomes Having a pacemaker, defibrillator, or any other type of metal implant
Sites / Locations
- Maastricht University Medical Centre +
Arms of the Study
Arm 1
Arm 2
Sham Comparator
Experimental
Non-heated sauna session
Heated sauna session
The test days will consist of sitting in an infrared sauna cabin (HM-LSE-3 Professional edition, Health Mate, Belgium). Participants will sit in an infrared sauna at 21° Celsius for a total of 40 minutes.
The test days will consist of sitting in an infrared sauna cabin (HM-LSE-3 Professional edition, Health Mate, Belgium). Participants will sit in an infrared sauna at 60° Celsius (humidity not controlled in an infrared sauna) for a total of 40 minutes.