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Active clinical trials for "Diabetes Mellitus, Type 1"

Results 481-490 of 2981

A Pilot Study to Assess the Feasibility of a Novel Non-invasive Technology to Measure Changing Blood...

Type 1 Diabetes MellitusType 1 Diabetes Mellitus With Hypoglycemia1 more

The primary aim of this study is to assess the feasibility of the Lab demo 1.0 and associated computational models to detect and track glucose changes noninvasively and transcutaneously in defined and dynamic states of glycemia.

Not yet recruiting18 enrollment criteria

The Effect of Digital Game-Based Diabetes Education on Quality of Life of Children With Type 1 Diabetes...

Type 1 Diabetes Mellitus

This research will be conducted to evaluate the effect of digital game-based diabetes education on the quality of life of children with Type 1 Diabetes Mellitus. HbA1c, diabetes knowledge, and Quality of Life in Children with Diabetes Mellitus Scale (PedsQL 3.0) score will be taken into account in assessing the quality of life for children with type 1 diabetes.

Not yet recruiting7 enrollment criteria

Impact of Insulin Deprivation and Hyperglycemia on Plasma Protein Synthesis in People With Type...

Type 1 Diabetes

This research is being done to better understand how insulin effects muscle, blood, and the body in people with Type 1 Diabetes.

Not yet recruiting33 enrollment criteria

Role of Adrenaline in in the Inflammatory Response in Diabetes

Inflammatory ResponseDiabetes type11 more

The primary aim of the present study is to study the effect of adrenaline administration on inflammatory parameters (e.g. leukocyte phenotype, cytokines, inflammatory proteins). Secondary objectives consist of the effect of adrenaline on atherogenic parameters. All participants will receive intravenous infusion of adrenaline for an hour We will draw blood at 7 time points, not including screening Participants will be asked to return for a total of 4 times Researchers will compare 2 groups, healthy individuals versus people with diabetes type 1 to see if the inflammatory reaction to adrenaline differs between these two groups.

Not yet recruiting25 enrollment criteria

Investigation of Hyposafe H02 Device in Patients With Type 1 Diabetes

Type 1 Diabetes

This clinical study is designed to collect data for further development of a hypoglycaemia notification algorithm. In addition, information regarding safety will be collected and analysed.

Not yet recruiting14 enrollment criteria

Therapeutic Strategies for Microvascular Dysfunction in Type 1 Diabetes

Diabetes MellitusType 11 more

The investigators will test the hypothesis that, in adults with type 1 diabetes (T1D), glucagon-like peptide-1 receptor agonism (GLP-1RA, i.e. dulaglutide) and exercise training each enhance insulin-mediated skeletal muscle microvascular perfusion via attenuating endothelial oxidative stress and thereby improving endothelial function.

Not yet recruiting22 enrollment criteria

REACHOUT Mental Health Support Mobile App

Type1diabetes

The purpose of this study is to investigate the effectiveness of participation in a 6-month peer-led mental health support program, delivered via a mobile app (REACHOUT), to adults with type 1 diabetes compared to a wait-list control condition. Participants will connect with a Peer-Supporter (an adult with type 1 diabetes trained in providing mental health support), and have access to the app features including a 24/7 chat room and face-to-face support delivered via virtual happy hours.

Not yet recruiting7 enrollment criteria

Happy Bob App in 9-13 Year-old Children

Type1diabetes

The purpose of the study is to evaluate the effectiveness of the Happy Bob -application on glycemic control in children aged 9-13 years with type 1 diabetes. Additionally, investigators evaluate the perceived burden on the diabetes treatment to families during the Happy Bob use, compared to conventional treatment (diabetes distress). This is a prospective, randomized, controlled study where primary endpoint is the change in time-in-range (TIR, 3.9-10 mmol/l) after Happy Bob application initiation. Secondary endpoints are HbA1c, time below range (TBR, <3.9 mmol/l), time above range (TAR, >10 mmol/l), mean sensor glucose (SG), standard deviation of SG, coefficient of variation (CV, SD/SGx100 (%)), number of boluses and diabetes distress evaluated by PAID (Problem Areas In Diabetes for parents and children/youth). A sample size of 40 subjects (20 in each groups, and assumed drop-out rate of 10%) would provide the trial with 80% power and type 1 error rate of 0.05 with the following assumption: 7% higher TIR during Happy Bob -use compared to conventional treatment with continuous glucose monitoring (CGM), with a standard deviation of 7.5% (based on Happy Bob marketing study). The inclusion criteria are 1) Type 1 diabetes diagnosis more than 6 months ago 2) Age 9-13 years and prepubertal 3) capability to use Happy Bob -app and continuous glucose monitoring (CGM). The exclusion criteria are psychiatric diagnosis and other conditions, which in the opinion of the investigator would put the participant at risk during the trial. The study includes 6 months study time with 2 standard outpatient clinic visits.

Not yet recruiting5 enrollment criteria

Impact of Telehealth Education in Diabetes Patients

Diabetes MellitusType 12 more

The goal of this clinical trial is to to evaluate the effectiveness of continuity of in-hospital care with the application of a structured telemonitoring protocol in self-care activities in patients with type 1 or type 2 Diabetes Mellitus or those who have an HbA1C level greater than or equal to 6.5% during hospitalization, regardless of the reason for hospitalization. The main question[s] it aims to answer are: • Is telehealth education effective for improving self-care for type 1 or type 2 Diabetes Mellitus or those with an HbA1C level greater than or equal to 6.5% during hospitalization will be included, regardless of the reason for hospitalization? Participants will answer the Diabetes Self-Care Activity Questionnaire Researchers will compare patients in the intervention group, in addition to the hospital's standard hospital guidance, will receive an educational approach through structured telemonitoring, reinforcing and validating the points addressed in the face-to-face guidance, which are considered the foundations of self-care.

Not yet recruiting5 enrollment criteria

BEAD-T1D: Building the Evidence to Address Disparities in Type 1 Diabetes

Type 1 Diabetes

Youth from low socioeconomic groups are at a systematic disadvantage in the provision of diabetes care, particularly diabetes technology which is associated with improvement in diabetes-specific outcomes. Thus, the type 1 diabetes community urgently need studies to understand and ameliorate the persistent worsening of disparities of diabetes management and outcomes in youth from low socioeconomic backgrounds. This proposed research will (1) improve representation of diverse youth in the literature, (2) address the gap in knowledge of barriers and promoters in publicly insured youth, and (3) identify and address factors of worsening disparity in diabetes technology.

Not yet recruiting5 enrollment criteria
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