A Study to Compare Different Drugs Used to Prevent Serious Bacterial Infections in HIV-Positive Children
Bacterial Infections, Pneumonia, Pneumocystis Carinii, HIV Infections
About this trial
This is an interventional treatment trial for Bacterial Infections focused on measuring Trimethoprim-Sulfamethoxazole Combination, Pneumonia, Pneumocystis carinii, Drug Therapy, Combination, Acquired Immunodeficiency Syndrome, Antiprotozoal Agents, AIDS-Related Complex, Azithromycin, Bacterial Infections, atovaquone
Eligibility Criteria
Inclusion Criteria Children may be eligible for this study if they: Are HIV-positive. Are between the age of 3 months and 18 months (consent of parent or guardian required). (This study has been changed. In an earlier version, patients up to 19 years old were eligible.) Are at risk for developing pneumonia and need preventive treatment. Have a CD4 count of less than 1,500 cells/mm3 if under 1 year of age or a CD4 count of less then 500 cells/mm3 if between 1 and 2 years of age. Exclusion Criteria Children will not be eligible for this study if they: Have an infection that requires treatment. Are allergic to atovaquone, azithromycin, or SMX/TMP. Have serious diarrhea for more than 1 week.
Sites / Locations
- Univ of Alabama at Birmingham - Pediatric
- Univ of South Alabama
- UCSD Med Ctr / Pediatrics / Clinical Sciences
- Long Beach Memorial (Pediatric)
- Children's Hosp of Los Angeles/UCLA Med Ctr
- Los Angeles County - USC Med Ctr
- Cedars Sinai / UCLA Med Ctr
- UCLA Med Ctr / Pediatric
- Harbor - UCLA Med Ctr / UCLA School of Medicine
- Children's Hosp of Oakland
- UCSF / Moffitt Hosp - Pediatric
- Children's Hosp of Denver
- Connecticut Children's Med Ctr
- Univ of Connecticut / Farmington
- Yale Univ Med School
- Howard Univ Hosp
- North Broward Hosp District
- Univ of Florida Gainesville
- Univ of Florida Health Science Ctr / Pediatrics
- Univ of Miami (Pediatric)
- Palm Beach County Health Dept
- Emory Univ Hosp / Pediatrics
- Med College of Georgia
- Cook County Hosp
- Univ of Illinois College of Medicine / Pediatrics
- Chicago Children's Memorial Hosp
- Univ of Chicago Children's Hosp
- Tulane Univ / Charity Hosp of New Orleans
- Earl K Long Early Intervention Clinic
- Univ of Maryland at Baltimore / Univ Med Ctr
- Johns Hopkins Hosp - Pediatric
- Children's Hosp of Boston
- Boston City Hosp / Pediatrics
- Baystate Med Ctr of Springfield
- Univ of Massachusetts Med School
- Children's Hosp of Michigan
- Univ of Mississippi Med Ctr
- Cooper Hosp - Univ Med Ctr / UMDNJ - New Jersey Med Schl
- UMDNJ - Robert Wood Johnson Med School / Pediatrics
- Univ of Medicine & Dentistry of New Jersey / Univ Hosp
- Saint Joseph's Hosp and Med Ctr/UMDNJ - New Jersey Med Schl
- Children's Hosp at Albany Med Ctr
- Bronx Lebanon Hosp Ctr
- Montefiore Med Ctr Adolescent AIDS Program
- SUNY - Brooklyn
- Children's Hosp Pact Prog / Children's Hosp of Buffalo
- North Shore Univ Hosp
- Schneider Children's Hosp
- Beth Israel Med Ctr / Pediatrics
- Bellevue Hosp / New York Univ Med Ctr
- Cornell Univ Med College
- Metropolitan Hosp Ctr
- Mount Sinai Med Ctr / Pediatrics
- Columbia Presbyterian Med Ctr
- Incarnation Children's Ctr / Columbia Presbyterian Med Ctr
- Harlem Hosp Ctr
- Univ of Rochester Med Ctr
- Univ of Rochester Medical Center
- State Univ of New York at Stony Brook
- SUNY Health Sciences Ctr at Syracuse / Pediatrics
- Duke Univ Med Ctr
- Columbus Children's Hosp
- Children's Hosp of Philadelphia
- Saint Christopher's Hosp for Children
- Med Univ of South Carolina
- Saint Jude Children's Research Hosp of Memphis
- Vanderbilt Univ Med Ctr
- Hermann Hosp / Univ Texas Health Science Ctr
- Texas Children's Hosp / Baylor Univ
- Children's Hosp of the King's Daughters
- Med College of Virginia
- Children's Hospital & Medical Center / Seattle ACTU
- Ramon Ruiz Arnau Univ Hosp / Pediatrics
- Univ of Puerto Rico / Univ Children's Hosp AIDS
- San Juan City Hosp