A Study to Evaluate the Use of Memantine In Combination With Anti-HIV Drugs to Treat AIDS Dementia Complex (ADC)
AIDS Dementia Complex, HIV Infections
About this trial
This is an interventional treatment trial for AIDS Dementia Complex focused on measuring Drug Therapy, Combination, Administration, Oral, AIDS Dementia Complex, Zidovudine, Anti-HIV Agents, Memantine
Eligibility Criteria
Inclusion Criteria You may be eligible for this study if you: Are HIV positive. Have been diagnosed with AIDS dementia complex (ADC). Have an estimated IQ of at least 70 (before the onset of ADC) or the ability to read at a 6th grade level. Have impaired mental skills. Are age18 or older. Exclusion Criteria You will not be eligible for this study if you: Have a history of a neurologic disease unrelated to HIV infection. Have a history of chronic seizures or head injuries. Have a history of central nervous system infections. Have certain cancers. Have any psychiatric illness. Have an active AIDS-defining opportunistic infection. Are pregnant or breast-feeding.
Sites / Locations
- UCLA CARE Center CRS
- Ucsf Aids Crs
- Univ. of Miami AIDS CRS
- Queens Med. Ctr.
- Univ. of Hawaii at Manoa, Leahi Hosp.
- Northwestern University CRS
- Cook County Hosp. CORE Ctr.
- The Univ. of Kentucky, Lexington A2405 CRS
- Bmc Actg Crs
- Beth Israel Deaconess - East Campus A0102 CRS
- Washington U CRS
- Univ. of Nebraska Med. Ctr., Durham Outpatient Ctr.
- SUNY - Buffalo, Erie County Medical Ctr.
- Beth Israel Med. Ctr. (Mt. Sinai)
- Mt. Sinai Med. Ctr. (N.Y.) A1801 CRS
- Mt. Sinai Med. Ctr. A0404 CRS
- Univ. of Rochester ACTG CRS
- Hosp. of the Univ. of Pennsylvania CRS
- University of Washington AIDS CRS