Back to resultsStudies of Patients With Skin Disease, Patients With Neurological Degenerations, and Normal Volunteers
Primary Purpose
Healthy, Muscular Dystrophy, Retinal Degeneration
Status
Completed
Phase
Locations
United States
Study Type
Observational
Intervention
Sponsored by
About this trial
This is an observational trial for Healthy focused on measuring Genetic Evaluation, Immunologic Evaluations, Inflammatory Skin Disease, Muscular Dystrophies, Neoplastic Skin Diseases, Neuronal Degenerations, Retinal Degenerations, Viral Diseases
Eligibility Criteria
Patients with skin diseases of presumed genetic, immunologic, or virologic origin are eligible. Patients with neurological degenerations are eligible, including patients with inflammatory, neoplastic and viral skin diseases and also heterozygous carriers of such inherited diseases. Volunteers without skin diseases are eligible, except children.
Sites / Locations
- National Cancer Institute (NCI)
Outcomes
Primary Outcome Measures
Secondary Outcome Measures
Full Information
NCT ID
NCT00001164
First Posted
November 3, 1999
Last Updated
March 4, 2008
Sponsor
National Cancer Institute (NCI)
1. Study Identification
Unique Protocol Identification Number
NCT00001164
Brief Title
Studies of Patients With Skin Disease, Patients With Neurological Degenerations, and Normal Volunteers
Official Title
Studies of Patients With Skin Disease, Patients With Neurological Degenerations, and Normal Volunteers
Study Type
Observational
2. Study Status
Record Verification Date
June 2000
Overall Recruitment Status
Completed
Study Start Date
July 1978 (undefined)
Primary Completion Date
undefined (undefined)
Study Completion Date
June 2000 (undefined)
3. Sponsor/Collaborators
Name of the Sponsor
National Cancer Institute (NCI)
4. Oversight
5. Study Description
Brief Summary
It is proposed that patients with skin disease due to presumed immunologic, genetic or viral-induced abnormalities, patients with neurological degenerations, and normal controls be evaluated with various in vitro studies of immunologic, genetic, and virologic function. This is to include studies of peripheral blood (cells and serum) as well as studies of skin obtained with a biopsy instrument. In addition, studies of gastrointestinal function will be performed where appropriate.
Detailed Description
It is proposed that patients with skin disease due to presumed immunologic, genetic or viral-induced abnormalities, patients with neurological degenerations, and normal controls be evaluated with various in vitro studies of immunologic, genetic, and virologic function. This is to include studies of peripheral blood (cells and serum) as well as studies of skin obtained with a biopsy instrument. In addition, studies of gastrointestinal function will be performed where appropriate.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Healthy, Muscular Dystrophy, Retinal Degeneration, Skin Diseases, Virus Diseases
Keywords
Genetic Evaluation, Immunologic Evaluations, Inflammatory Skin Disease, Muscular Dystrophies, Neoplastic Skin Diseases, Neuronal Degenerations, Retinal Degenerations, Viral Diseases
7. Study Design
10. Eligibility
Sex
All
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Patients with skin diseases of presumed genetic, immunologic, or virologic origin are eligible.
Patients with neurological degenerations are eligible, including patients with inflammatory, neoplastic and viral skin diseases and also heterozygous carriers of such inherited diseases.
Volunteers without skin diseases are eligible, except children.
Facility Information:
Facility Name
National Cancer Institute (NCI)
City
Bethesda
State/Province
Maryland
ZIP/Postal Code
20892
Country
United States
12. IPD Sharing Statement
Citations:
PubMed Identifier
164028
Citation
Kraemer KH, Coon HG, Petinga RA, Barrett SF, Rahe AE, Robbins JH. Genetic heterogeneity in xeroderma pigmentosum: complementation groups and their relationship to DNA repair rates. Proc Natl Acad Sci U S A. 1975 Jan;72(1):59-63. doi: 10.1073/pnas.72.1.59.
Results Reference
background
PubMed Identifier
972257
Citation
Yaoita H, Katz SI. Immunoelectronmicroscopic localization of IgA in skin of patients with dermatitis herpetiformis. J Invest Dermatol. 1976 Oct;67(4):502-6. doi: 10.1111/1523-1747.ep12664534.
Results Reference
background
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Studies of Patients With Skin Disease, Patients With Neurological Degenerations, and Normal Volunteers
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