Evaluation of HIV-Negative Patients With Low CD4+ T Lymphocyte Counts
CD4 Lymphocytopenia, Idiopathic CD4 Positive T Lymphocytopenia
About this trial
This is an observational trial for CD4 Lymphocytopenia focused on measuring HIV Negative, CD4 Deficiency, Retrovirus
Eligibility Criteria
INCLUSION CRITERIA Adults greater than or equal to 18 years of age. CD4 count less than 300 cells/mmL on 2 consecutive samples. Uninfected by HIV as determined by ELISA with confirmatory Western Blot Absence of disease or treatment that might provide a reasonable alternative explanation for the CD4 cell count or might confound the evaluation. Examples of such diseases would be any acute, severe medical illness that had not resolved when CD4 cell counts were obtained; active tuberculosis; leukemia or lymphoma; or previously characterized immunodeficiency disorder. Treatment that that might provide a reasonable alternative explanation includes chemotherapy over a field that could affect bone marrow or supraphysiologic glucocorticoid therapy. Capable of providing informed consent.
Sites / Locations
- National Institute of Allergy and Infectious Diseases (NIAID)