Identification of Genes Associated With Lung Disease in Patients With Rheumatoid Arthritis
Healthy, Pulmonary Fibrosis, Rheumatoid Arthritis
About this trial
This is an observational trial for Healthy focused on measuring Interstitial Lung Disease, Inherited Disease, Genetic Markers, Alpha 1 Protease Inhibitor, DNA Mutations, Rheumatoid Arthritis, Pulmonary Fibrosis, Normal Volunteer
Eligibility Criteria
INCLUSION CRITERIA: Individuals 21 years of age or older with any of the following: RA (based on 1987 American College of Rheumatology Revised Criteria for the Classification of RA) with PF (biopsy-proven), or RA-only, or Biopsy-proven idiopathic PF-only, or Healthy research volunteers. EXCLUSION CRITERIA: Individuals with any of the following: Inhalational exposure to fibrogenic fibers or dusts (e.g., asbestos, silica, coal, beryllium). Chronic pulmonary disorders other than pulmonary fibrosis. Other collagen vascular disorders (e.g., systemic lupus erythematosus, scleroderma, polymyositis, mixed connective tissue disease). Non-rheumatoid arthritis. Viral infections associated with PF (e.g., hepatitis B, hepatitis C, human immunodeficiency virus). Pregnancy.
Sites / Locations
- National Institutes of Health Clinical Center, 9000 Rockville Pike