Effectiveness of an HIV Vaccine in HIV-Negative Adults in North America Who Are at Risk of HIV Infection
HIV Infections, HIV Seronegativity
About this trial
This is an interventional prevention trial for HIV Infections focused on measuring HIV-1, Dose-Response Relationship, Drug, Acquired Immunodeficiency Syndrome, AIDS Vaccines, Sexually Transmitted Diseases, Risk Factors, HIV Seronegativity, Antigens, Viral, Alum Compounds
Eligibility Criteria
Exclusion Criteria You will not be eligible for this study if you: Use injection drugs. Have a history of any serious diseases or conditions, including lymphoma. Have ever received an HIV vaccine. Have taken post-exposure treatment to prevent HIV infection within 4 weeks prior to study entry. Are planning to take other HIV vaccines during this study. Are pregnant. Have taken certain medications or received certain therapies, including chemotherapy and radiation. Have received certain vaccines within 2-4 weeks prior to study entry. You may be eligible for this study if you: Are HIV-negative. Are between 18 and 60 years old. Are available for 3 years of follow-up. Agree to use effective methods of birth control during the study and for 90 days after. Are one of the following: A woman who is currently in a sexual relationship with an HIV-positive man. A woman who has had more than one male partner and at least one sexually transmitted disease (STD) within the past 12 months. A man who has sex with men and has had anal intercourse within the past 12 months. (You will not be eligible if you have been in the same relationship with only one HIV-negative man for at least 12 months.)
Sites / Locations
- Univ of Alabama at Birmingham
- Phoenix Body Positive
- Arizona Clinical Research Ctr Inc
- Univ of California / UCI Med Ctr
- ViRx Inc
- Univ of California - Davis Med Ctr / CARES
- San Francisco Dept of Hlth / AIDS Office
- San Francisco Gen Hosp
- UCSF - San Francisco Gen Hosp
- Santa Clara Public Health Dept
- AIDS Research Alliance
- Denver Hlth and Hosp Authority / Dept of Pub Hlth
- Johns Hopkins Univ / Ctr for Immun Rsch
- IDC Research Initiative
- Community AIDS Resource Inc
- Community AIDS Resource Inc
- Boulevard Comprehensive Care Ctr
- Community AIDS Resource Inc
- Infectious Disease Research Institute
- Palm Beach Research Ctr
- AIDS Research Consortium of Atlanta
- Univ of Hawaii
- Chicago Ctr for Clinical Research
- Univ of Illinois at Chicago / Dept of Medicine
- Howard Brown Health Ctr
- Community Hosp Indianapolis
- Louisiana State Univ Med Ctr / Infect Diseases
- Fenway Community Health Ctr
- Abbott Northwestern Hosp
- Hennepin County Med Ctr
- Park Nicollet Med Ctr / Hlth Education
- St Paul Public Health
- Kansas City AIDS Research Consortium
- Saint Louis Univ Hosp / Ctr for Vacc Dev
- Wellness Ctr / Las Vegas
- New Jersey Community Research Initiative
- Univ of New Mexico Hlth Sciences Ctr / Dept of Med
- Albany Med College / Div of HIV Medicine
- New York Blood Ctr
- Project Achieve - New York Blood Ctr - Women only
- AIDS Services Erie County Med Ctr
- St Luke Roosevelt Hosp
- New York Univ Med Ctr / Dept of Environmental Med
- Mount Sinai Med Ctr / Jack Martin Fund Clinic
- Dutchess County Dept of Health
- Univ of Rochester Med Ctr
- Nalle Clinic / Clinical Research Dept
- PW Clinical Research / LLC
- Case Western Reserve Univ
- Ohio State Univ / ACTU-Univ Clinic
- Clinical Pharmaceutical Trials Inc / St Johns Doctors Bldg
- Research and Education Group
- Philadelphia FIGHT
- Univ of Pittsburgh Med School
- Mem Hosp of Rhode Island
- Miriam Hosp
- Omega Med Research
- Nelson Tebedo Health Resource Ctr
- Oak Lawn Physicians / North TX Ctr for AIDS & Cln Rsch
- Univ of Texas Med Branch Ctr for Clinical Studies
- UTMB Ctr for Clinical Studies / St John Prof Bldg
- Univ of Washington
- Wisconsin AIDS Research Consortium
- St Pauls Hosp
- Ctr Hosp de Universite de Montreal (CHUM)
- Municipal Health Service
- Clinical Research of Puerto Rico Inc