Combination Chemotherapy and Bone Marrow and/or Peripheral Stem Cell Transplantation in Treating Patients With Non-Hodgkin's Lymphoma

DISEASE CHARACTERISTICS: Histologically proven relapsed or refractory, stage I-IV, intermediate- or high-grade non-Hodgkin's lymphoma Eligible subtypes: Diffuse small cleaved cell Diffuse mixed (small and large cell) Diffuse large cell Large cell immunoblastic Lymphoblastic Small noncleaved cell High-grade histology patients should first be considered for Protocol TUHSC-1520 Must have chemosensitive disease, defined by 1 of the following conditions: Response to initial chemotherapy without obtaining complete response (CR)(refractory lymphoma) Relapse after chemotherapy-induced CR if tumor volume reduced by at least 25% for more than 1 month after completion of 1-3 courses of salvage chemotherapy (chemosensitive relapse) No chemoresistant disease, defined by the following conditions: Unresponsive or progressive disease during initial chemotherapy Relapse after chemotherapy-induced CR if tumor volume not reduced by at least 25% after completion of 1-3 courses salvage chemotherapy (chemoresistant relapse) No CNS involvement by lymphoma Syngeneic bone marrow transplantation offered to patients with consenting identical twin donor NOTE: A new classification scheme for adult non-Hodgkin's lymphoma has been adopted by PDQ. The terminology of "indolent" or "aggressive" lymphoma will replace the former terminology of "low", "intermediate", or "high" grade lymphoma. However, this protocol uses the former terminology. PATIENT CHARACTERISTICS: Age: 15 to 60 (physically fit patients up to age 70 may be considered) Performance status: ECOG 0-2 Life expectancy: Not specified Hematopoietic: Not specified Hepatic: Bilirubin no greater than 2.0 mg/dL AST and ALT not persistently greater than 2 times normal Renal: Creatinine less than 1.8 mg/dL Cardiovascular: Cardiac ejection fraction at least 45% Pulmonary: DLCO, FEV_1, and FVC at least 50% predicted Resting pO_2 at least 70 mm Hg Other: HIV negative No other concurrent disease that would limit life expectancy No active infection No severe neurologic or emotional disorders Not pregnant Fertile patients must use effective contraception Adequate psychological support available PRIOR CONCURRENT THERAPY: Biologic therapy Not specified Chemotherapy See Disease Characteristics Endocrine therapy Not specified Radiotherapy Not specified Surgery Not specified