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Combination Chemotherapy Compared With No Treatment Following Surgery in Treating Patients With Non-small Cell Lung Cancer

Primary Purpose

Lung Cancer

Status
Completed
Phase
Phase 3
Locations
International
Study Type
Interventional
Intervention
cisplatin
etoposide
vinblastine sulfate
vindesine
vinorelbine tartrate
radiation therapy
Sponsored by
Gustave Roussy, Cancer Campus, Grand Paris
About
Eligibility
Locations
Outcomes
Full info

About this trial

This is an interventional treatment trial for Lung Cancer focused on measuring stage I non-small cell lung cancer, stage II non-small cell lung cancer, stage III non-small cell lung cancer, squamous cell lung cancer, large cell lung cancer, adenocarcinoma of the lung, adenosquamous cell lung cancer

Eligibility Criteria

18 Years - 75 Years (Adult, Older Adult)All SexesDoes not accept healthy volunteers

DISEASE CHARACTERISTICS: Histologically documented non-small cell lung cancer Any non-small cell histology eligible Pathologic stage I/II/III disease that is completely resected with microscopically clear margins within 60 days of entry (30 days preferred) PATIENT CHARACTERISTICS: Age: 18 to 75 Performance status: Not specified Hematopoietic: Not specified Hepatic: Not specified Renal: Not specified Other: No clear contraindication to chemotherapy No second malignancy except: Nonmelanomatous skin cancer Carcinoma in situ of the cervix PRIOR CONCURRENT THERAPY: Biologic therapy: No prior immunotherapy Chemotherapy: No prior chemotherapy Endocrine therapy: Not specified Radiotherapy: No prior thoracic radiotherapy Surgery: Complete resection required prior to entry

Sites / Locations

  • Comprehensive Cancer Center at JFK Medical Center
  • Massachusetts General Hospital Cancer Center
  • Getlac
  • South Eastern Sydney Area Health Service
  • Royal Adelaide Hospital
  • Peter MacCallum Cancer Institute
  • Western Hospital
  • Alfred Hospital
  • Royal Melbourne Hospital
  • AKH Vienna
  • A.Z. St. Jan
  • Universitair Ziekenhuis Antwerpen
  • U.Z. Gasthuisberg
  • AZ Zusters Van Barmhartigheid
  • Sint Elizabeth Ziekenhuis
  • Porto Alegre Hospital
  • Instituto Nacional de Cancer
  • University of Clementino Fraga
  • Hospital A.C. Camargo
  • Clinica Las Nieves
  • Hospital Militar Central
  • Instituto Nacional De Cancerologia
  • Chest Disease Clinic, Charles University
  • National Cancer Institute of Egypt
  • Institute for Lung Diseases
  • Centre Hospitalier Regional et Universitaire d'Angers
  • Centre Paul Papin
  • C.H. Armentieres
  • Centre Hospital General Robert Ballanger
  • C.H. Henri Mondor
  • Clinique Hauts De Seine Bagneux
  • C.H.G. Beauvais
  • Hopital Avicenne
  • C.M.C. Du Cedre
  • Institut Bergonie
  • CHU de Caen
  • Centre Regional Francois Baclesse
  • Centre Du Meridien
  • Hopital Fontenoy
  • Hopital Antoine Beclere
  • Centre Hospitalier General
  • Hopital Intercommunal De Creteil
  • Centre de Lute Contre le Cancer,Georges-Francois Leclerc
  • Hopital D'Etampes
  • C.H. De Grasse
  • Centre Hospitalier de Lagny
  • C.H.G. Du Havre-Hopital J. Monod
  • Centre Oscar Lambret
  • Centre Leon Berard
  • Assistance Publique Hopitaux de Marseille Hopitaux Sud
  • C.H. Nord Mayenne
  • Hopital Clinique Claude Bernard
  • Centre de Radiologie et de Traitement des Tumeurs
  • Hopital Arnaud de Villeneuve
  • Clinique Hartmann
  • Centre Antoine Lacassagne
  • Institut Mutualiste Montsouris
  • Hospital Saint-Joseph
  • Institut Curie - Section Medicale
  • Hopital Tenon
  • C.H.G. De Pau
  • Hopital Jean Bernard
  • CHU De Pontchaillou
  • Centre Hospitalier de Saint-Brieuc
  • Centre du Rouget
  • C.H. De Sens
  • Hopitaux Universitaire de Strasbourg
  • C.H.G. Troyes
  • Centre Alexis Vautrin
  • Institut Gustave Roussy
  • University Hospital of Heraklion
  • Evangelismos Hospital
  • Athens University-Laikon General Hospital
  • Sismanoglio Hospital
  • Sotiria Hospital Chest Diseases
  • Metaxa's Memorial Cancer Hospital
  • University of Patras Medical School
  • George Papanicolaou General Hospital
  • Kaplan Hospital
  • Tel-Aviv Medical Center
  • Istituto Europeo Di Oncologia
  • Federico II University Medical School
  • Ospedale Cervello
  • Ospedale Oncologico M. Ascoli
  • Ospedale Civile Rimini
  • Ospedale San Filippo Neri
  • Clinica Ars Medica
  • Istituto Di Clinica Chirurgica
  • Ospedale Molinette
  • Universita Degli Studi di Udine
  • Ospedale Di Borgo Trento
  • National Kinki Central Hospital
  • Lithuanian Oncology Center
  • Institute of Radiotherapy and Oncology
  • Institut National D'Oncologie
  • University of Tromso
  • Lung Centre of the Philippines
  • Bialystok Medical School
  • Institute of Oncology
  • Department of Children Hematology/Oncology University of Medicine Wroclaw
  • K. Dluski Hospital-Medical Academy
  • Regional Hospital for Lung Disease
  • Hospital Santa Maria
  • University of Ljubljana
  • Groote Schuur Hospital, Cape Town
  • Sandton Oncology Centre
  • Park Lane Oncology Practice
  • Institut Catala d'Oncologia - Hospital Duran i Reynals
  • Hospital Virgen de las Nieves
  • Hospital Arnau Vilanova
  • Sahlgrenska University Hospital
  • University Hospital of Linkoping
  • Lund University Hospital
  • Karolinska Hospital
  • University Hospital - Uppsala
  • University Hospital
  • Ospedale San Giovanni
  • Ratisches Kantons und Regionalspital
  • Hopital Cantonal Universitaire de Geneva
  • Kantonsspital, Luzern
  • City Hospital Triemli
  • Universitaetsspital
  • Hopital Universitaire F. Bourguiba

Outcomes

Primary Outcome Measures

Secondary Outcome Measures

Full Information

First Posted
November 1, 1999
Last Updated
March 26, 2013
Sponsor
Gustave Roussy, Cancer Campus, Grand Paris
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1. Study Identification

Unique Protocol Identification Number
NCT00002823
Brief Title
Combination Chemotherapy Compared With No Treatment Following Surgery in Treating Patients With Non-small Cell Lung Cancer
Official Title
A LARGE-SCALE TRIAL EVALUATING ADJUVANT CHEMOTHERAPY AFTER CURATIVE RESECTION OF NON-SMALL CELL LUNG CANCER
Study Type
Interventional

2. Study Status

Record Verification Date
April 2011
Overall Recruitment Status
Completed
Study Start Date
February 1995 (undefined)
Primary Completion Date
January 2001 (Actual)
Study Completion Date
undefined (undefined)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Gustave Roussy, Cancer Campus, Grand Paris

4. Oversight

5. Study Description

Brief Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known if combination chemotherapy given after surgery is more effective than surgery alone for non-small cell lung cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of combination chemotherapy following surgery with that of surgery alone in treating patients who have stage I, stage II, or stage IIIA non-small cell lung cancer.
Detailed Description
OBJECTIVES: I. Compare the impact on overall survival of adjuvant cisplatin and either a vinca alkaloid or etoposide (with or without radiotherapy) vs. no adjuvant chemotherapy in patients with completely resected stage I/II/III non-small cell lung cancer. II. Assess the frequency of treatment-related deaths and severe toxic effects. III. Describe the patterns of failure, second malignancies, and toxic effects associated with each treatment regimen. OUTLINE: This is a randomized, multicenter study. Patients are stratified by participating institution, type of prior surgery, and pathologic stage. Each participating center will determine which combination chemotherapy regimen and which of three cisplatin doses will be given to all patients treated at that center. The treatment group receives cisplatin combined with either vindesine, vinblastine, vinorelbine, or etoposide every 3-4 weeks for 3-4 courses, depending on the dose of cisplatin. The second group receives no adjuvant chemotherapy. Treating institutions determine prior to entering the trial which patients receive adjuvant radiotherapy: none; those with node-positive disease; those with N1 disease only; those with N2 disease only; or those eligible for a randomized radiotherapy trial. For patients in the treatment group, radiotherapy begins 3-4 weeks after the last course. Patients are followed at 6 months, then annually. PROJECTED ACCRUAL: A maximum of 3,300 patients will be accrued for this study.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Lung Cancer
Keywords
stage I non-small cell lung cancer, stage II non-small cell lung cancer, stage III non-small cell lung cancer, squamous cell lung cancer, large cell lung cancer, adenocarcinoma of the lung, adenosquamous cell lung cancer

7. Study Design

Primary Purpose
Treatment
Study Phase
Phase 3
Allocation
Randomized
Enrollment
3300 (Anticipated)

8. Arms, Groups, and Interventions

Intervention Type
Drug
Intervention Name(s)
cisplatin
Intervention Type
Drug
Intervention Name(s)
etoposide
Intervention Type
Drug
Intervention Name(s)
vinblastine sulfate
Intervention Type
Drug
Intervention Name(s)
vindesine
Intervention Type
Drug
Intervention Name(s)
vinorelbine tartrate
Intervention Type
Radiation
Intervention Name(s)
radiation therapy

10. Eligibility

Sex
All
Minimum Age & Unit of Time
18 Years
Maximum Age & Unit of Time
75 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
DISEASE CHARACTERISTICS: Histologically documented non-small cell lung cancer Any non-small cell histology eligible Pathologic stage I/II/III disease that is completely resected with microscopically clear margins within 60 days of entry (30 days preferred) PATIENT CHARACTERISTICS: Age: 18 to 75 Performance status: Not specified Hematopoietic: Not specified Hepatic: Not specified Renal: Not specified Other: No clear contraindication to chemotherapy No second malignancy except: Nonmelanomatous skin cancer Carcinoma in situ of the cervix PRIOR CONCURRENT THERAPY: Biologic therapy: No prior immunotherapy Chemotherapy: No prior chemotherapy Endocrine therapy: Not specified Radiotherapy: No prior thoracic radiotherapy Surgery: Complete resection required prior to entry
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Thierry L. Le Chevalier, MD
Organizational Affiliation
Gustave Roussy, Cancer Campus, Grand Paris
Official's Role
Study Chair
Facility Information:
Facility Name
Comprehensive Cancer Center at JFK Medical Center
City
Atlantis
State/Province
Florida
ZIP/Postal Code
33462
Country
United States
Facility Name
Massachusetts General Hospital Cancer Center
City
Boston
State/Province
Massachusetts
ZIP/Postal Code
02114
Country
United States
Facility Name
Getlac
City
Buenos Aires
ZIP/Postal Code
1638
Country
Argentina
Facility Name
South Eastern Sydney Area Health Service
City
Randwick
State/Province
New South Wales
ZIP/Postal Code
2031
Country
Australia
Facility Name
Royal Adelaide Hospital
City
Adelaide
State/Province
South Australia
ZIP/Postal Code
5000
Country
Australia
Facility Name
Peter MacCallum Cancer Institute
City
East Melbourne
State/Province
Victoria
ZIP/Postal Code
8006
Country
Australia
Facility Name
Western Hospital
City
Melbourne
State/Province
Victoria
ZIP/Postal Code
3011
Country
Australia
Facility Name
Alfred Hospital
City
Melbourne
State/Province
Victoria
ZIP/Postal Code
3181
Country
Australia
Facility Name
Royal Melbourne Hospital
City
Parkville
State/Province
Victoria
ZIP/Postal Code
3050
Country
Australia
Facility Name
AKH Vienna
City
Vienna
ZIP/Postal Code
A-1090
Country
Austria
Facility Name
A.Z. St. Jan
City
Brugge
ZIP/Postal Code
8000
Country
Belgium
Facility Name
Universitair Ziekenhuis Antwerpen
City
Edegem
ZIP/Postal Code
B-2650
Country
Belgium
Facility Name
U.Z. Gasthuisberg
City
Leuven
ZIP/Postal Code
B-3000
Country
Belgium
Facility Name
AZ Zusters Van Barmhartigheid
City
Ronse
ZIP/Postal Code
B-9600
Country
Belgium
Facility Name
Sint Elizabeth Ziekenhuis
City
Zottegem
ZIP/Postal Code
9620
Country
Belgium
Facility Name
Porto Alegre Hospital
City
Porto Alegre
State/Province
Rio Grande do Sul
ZIP/Postal Code
90035--003
Country
Brazil
Facility Name
Instituto Nacional de Cancer
City
Rio de Janeiro
ZIP/Postal Code
Cep 2-0230
Country
Brazil
Facility Name
University of Clementino Fraga
City
Rio De Janeiro
Country
Brazil
Facility Name
Hospital A.C. Camargo
City
Sao Paulo
ZIP/Postal Code
01509--010
Country
Brazil
Facility Name
Clinica Las Nieves
City
Santiago
Country
Chile
Facility Name
Hospital Militar Central
City
Bogota
Country
Colombia
Facility Name
Instituto Nacional De Cancerologia
City
Bogota
Country
Colombia
Facility Name
Chest Disease Clinic, Charles University
City
Prague (Praha)
ZIP/Postal Code
162 00
Country
Czech Republic
Facility Name
National Cancer Institute of Egypt
City
Cairo
Country
Egypt
Facility Name
Institute for Lung Diseases
City
Belgrade
ZIP/Postal Code
11000
Country
Former Yugoslavia
Facility Name
Centre Hospitalier Regional et Universitaire d'Angers
City
Angers
ZIP/Postal Code
49033
Country
France
Facility Name
Centre Paul Papin
City
Angers
ZIP/Postal Code
49036
Country
France
Facility Name
C.H. Armentieres
City
Armentieres
ZIP/Postal Code
59427
Country
France
Facility Name
Centre Hospital General Robert Ballanger
City
Aulnay Sous Bois
ZIP/Postal Code
93602
Country
France
Facility Name
C.H. Henri Mondor
City
Aurillac
ZIP/Postal Code
15002
Country
France
Facility Name
Clinique Hauts De Seine Bagneux
City
Bagneux
ZIP/Postal Code
92220
Country
France
Facility Name
C.H.G. Beauvais
City
Beauvais
ZIP/Postal Code
60021
Country
France
Facility Name
Hopital Avicenne
City
Bobigny
ZIP/Postal Code
93009
Country
France
Facility Name
C.M.C. Du Cedre
City
Bois Guillaume (Rouen)
ZIP/Postal Code
76235
Country
France
Facility Name
Institut Bergonie
City
Bordeaux
ZIP/Postal Code
33076
Country
France
Facility Name
CHU de Caen
City
Caen
ZIP/Postal Code
14033
Country
France
Facility Name
Centre Regional Francois Baclesse
City
Caen
ZIP/Postal Code
14076
Country
France
Facility Name
Centre Du Meridien
City
Cannes
ZIP/Postal Code
06400
Country
France
Facility Name
Hopital Fontenoy
City
Chartres
ZIP/Postal Code
28018
Country
France
Facility Name
Hopital Antoine Beclere
City
Clamart
ZIP/Postal Code
92141
Country
France
Facility Name
Centre Hospitalier General
City
Compiegne
ZIP/Postal Code
60321
Country
France
Facility Name
Hopital Intercommunal De Creteil
City
Creteil
ZIP/Postal Code
94010
Country
France
Facility Name
Centre de Lute Contre le Cancer,Georges-Francois Leclerc
City
Dijon
ZIP/Postal Code
21079
Country
France
Facility Name
Hopital D'Etampes
City
Etampes
ZIP/Postal Code
91150
Country
France
Facility Name
C.H. De Grasse
City
Grasse
ZIP/Postal Code
06130
Country
France
Facility Name
Centre Hospitalier de Lagny
City
Lagny
ZIP/Postal Code
77405
Country
France
Facility Name
C.H.G. Du Havre-Hopital J. Monod
City
Le Havre
ZIP/Postal Code
76083
Country
France
Facility Name
Centre Oscar Lambret
City
Lille
ZIP/Postal Code
59020
Country
France
Facility Name
Centre Leon Berard
City
Lyon
ZIP/Postal Code
69373
Country
France
Facility Name
Assistance Publique Hopitaux de Marseille Hopitaux Sud
City
Marseille
ZIP/Postal Code
13274
Country
France
Facility Name
C.H. Nord Mayenne
City
Mayenne
ZIP/Postal Code
53013
Country
France
Facility Name
Hopital Clinique Claude Bernard
City
Metz
ZIP/Postal Code
57070
Country
France
Facility Name
Centre de Radiologie et de Traitement des Tumeurs
City
Meudon-La-Foret
ZIP/Postal Code
92360
Country
France
Facility Name
Hopital Arnaud de Villeneuve
City
Montpellier
ZIP/Postal Code
34295
Country
France
Facility Name
Clinique Hartmann
City
Neuilly sur Seine
ZIP/Postal Code
92200
Country
France
Facility Name
Centre Antoine Lacassagne
City
Nice
ZIP/Postal Code
06189
Country
France
Facility Name
Institut Mutualiste Montsouris
City
Paris
ZIP/Postal Code
75013
Country
France
Facility Name
Hospital Saint-Joseph
City
Paris
ZIP/Postal Code
75014
Country
France
Facility Name
Institut Curie - Section Medicale
City
Paris
ZIP/Postal Code
75248
Country
France
Facility Name
Hopital Tenon
City
Paris
ZIP/Postal Code
75970
Country
France
Facility Name
C.H.G. De Pau
City
Pau
ZIP/Postal Code
64000
Country
France
Facility Name
Hopital Jean Bernard
City
Poitiers
ZIP/Postal Code
86021
Country
France
Facility Name
CHU De Pontchaillou
City
Rennes
ZIP/Postal Code
35033
Country
France
Facility Name
Centre Hospitalier de Saint-Brieuc
City
Saint-Brieuc
ZIP/Postal Code
22023
Country
France
Facility Name
Centre du Rouget
City
Sarcelles
ZIP/Postal Code
95250
Country
France
Facility Name
C.H. De Sens
City
Sens
ZIP/Postal Code
89106
Country
France
Facility Name
Hopitaux Universitaire de Strasbourg
City
Strasbourg
ZIP/Postal Code
67091
Country
France
Facility Name
C.H.G. Troyes
City
Troyes
ZIP/Postal Code
10003
Country
France
Facility Name
Centre Alexis Vautrin
City
Vandoeuvre-les-Nancy
ZIP/Postal Code
54511
Country
France
Facility Name
Institut Gustave Roussy
City
Villejuif
ZIP/Postal Code
F-94805
Country
France
Facility Name
University Hospital of Heraklion
City
Iraklion (Heraklion)
State/Province
Crete
ZIP/Postal Code
71110
Country
Greece
Facility Name
Evangelismos Hospital
City
Athens
ZIP/Postal Code
10676
Country
Greece
Facility Name
Athens University-Laikon General Hospital
City
Athens
ZIP/Postal Code
11527
Country
Greece
Facility Name
Sismanoglio Hospital
City
Athens
ZIP/Postal Code
15126
Country
Greece
Facility Name
Sotiria Hospital Chest Diseases
City
Athens
Country
Greece
Facility Name
Metaxa's Memorial Cancer Hospital
City
Piraeus
ZIP/Postal Code
18537
Country
Greece
Facility Name
University of Patras Medical School
City
Rio Patras
ZIP/Postal Code
GR-26500
Country
Greece
Facility Name
George Papanicolaou General Hospital
City
Thessaloniki
ZIP/Postal Code
57010
Country
Greece
Facility Name
Kaplan Hospital
City
Rehovot
ZIP/Postal Code
76100
Country
Israel
Facility Name
Tel-Aviv Medical Center
City
Tel-Aviv
ZIP/Postal Code
62995
Country
Israel
Facility Name
Istituto Europeo Di Oncologia
City
Milano
ZIP/Postal Code
20141
Country
Italy
Facility Name
Federico II University Medical School
City
Naples
ZIP/Postal Code
80131
Country
Italy
Facility Name
Ospedale Cervello
City
Palermo
ZIP/Postal Code
90146
Country
Italy
Facility Name
Ospedale Oncologico M. Ascoli
City
Palermo
Country
Italy
Facility Name
Ospedale Civile Rimini
City
Rimini
ZIP/Postal Code
47037
Country
Italy
Facility Name
Ospedale San Filippo Neri
City
Rome
ZIP/Postal Code
00135
Country
Italy
Facility Name
Clinica Ars Medica
City
Rome
ZIP/Postal Code
00191
Country
Italy
Facility Name
Istituto Di Clinica Chirurgica
City
Torino
ZIP/Postal Code
10126
Country
Italy
Facility Name
Ospedale Molinette
City
Turin
ZIP/Postal Code
10126
Country
Italy
Facility Name
Universita Degli Studi di Udine
City
Udine
ZIP/Postal Code
33100
Country
Italy
Facility Name
Ospedale Di Borgo Trento
City
Verona
ZIP/Postal Code
37126
Country
Italy
Facility Name
National Kinki Central Hospital
City
Osaka
ZIP/Postal Code
591
Country
Japan
Facility Name
Lithuanian Oncology Center
City
Vilnius
ZIP/Postal Code
2600
Country
Lithuania
Facility Name
Institute of Radiotherapy and Oncology
City
Skopje
ZIP/Postal Code
91000
Country
Macedonia, The Former Yugoslav Republic of
Facility Name
Institut National D'Oncologie
City
Rabat
Country
Morocco
Facility Name
University of Tromso
City
Tromso
ZIP/Postal Code
N-9037
Country
Norway
Facility Name
Lung Centre of the Philippines
City
Quezon City Diliman
ZIP/Postal Code
1100
Country
Philippines
Facility Name
Bialystok Medical School
City
Bialystok
ZIP/Postal Code
15276
Country
Poland
Facility Name
Institute of Oncology
City
Lodz
ZIP/Postal Code
93509
Country
Poland
Facility Name
Department of Children Hematology/Oncology University of Medicine Wroclaw
City
Wroclaw
ZIP/Postal Code
50345
Country
Poland
Facility Name
K. Dluski Hospital-Medical Academy
City
Wroclaw
ZIP/Postal Code
53 439
Country
Poland
Facility Name
Regional Hospital for Lung Disease
City
Zdunowo
ZIP/Postal Code
20
Country
Poland
Facility Name
Hospital Santa Maria
City
Lisbon (Lisboa)
ZIP/Postal Code
1699
Country
Portugal
Facility Name
University of Ljubljana
City
Ljubljana
ZIP/Postal Code
61105
Country
Slovenia
Facility Name
Groote Schuur Hospital, Cape Town
City
Cape Town
ZIP/Postal Code
7925
Country
South Africa
Facility Name
Sandton Oncology Centre
City
Johannesburg
ZIP/Postal Code
2121
Country
South Africa
Facility Name
Park Lane Oncology Practice
City
Johannesburg
Country
South Africa
Facility Name
Institut Catala d'Oncologia - Hospital Duran i Reynals
City
Barcelona
ZIP/Postal Code
08907
Country
Spain
Facility Name
Hospital Virgen de las Nieves
City
Granada
ZIP/Postal Code
18014
Country
Spain
Facility Name
Hospital Arnau Vilanova
City
Valencia
ZIP/Postal Code
46015
Country
Spain
Facility Name
Sahlgrenska University Hospital
City
Gothenburg (Goteborg)
ZIP/Postal Code
S-413 45
Country
Sweden
Facility Name
University Hospital of Linkoping
City
Linkoping
ZIP/Postal Code
S-581 85
Country
Sweden
Facility Name
Lund University Hospital
City
Lund
ZIP/Postal Code
S-22185
Country
Sweden
Facility Name
Karolinska Hospital
City
Stockholm
ZIP/Postal Code
S-171 76
Country
Sweden
Facility Name
University Hospital - Uppsala
City
Uppsala
ZIP/Postal Code
S-751 85
Country
Sweden
Facility Name
University Hospital
City
Basel
ZIP/Postal Code
CH-4031
Country
Switzerland
Facility Name
Ospedale San Giovanni
City
Bellinzona
ZIP/Postal Code
CH-6500
Country
Switzerland
Facility Name
Ratisches Kantons und Regionalspital
City
Chur
ZIP/Postal Code
CH-7000
Country
Switzerland
Facility Name
Hopital Cantonal Universitaire de Geneva
City
Geneva
ZIP/Postal Code
CH-1211
Country
Switzerland
Facility Name
Kantonsspital, Luzern
City
Luzern (Lucerne)
ZIP/Postal Code
CH-6000
Country
Switzerland
Facility Name
City Hospital Triemli
City
Zurich
ZIP/Postal Code
8063
Country
Switzerland
Facility Name
Universitaetsspital
City
Zurich
ZIP/Postal Code
CH-8091
Country
Switzerland
Facility Name
Hopital Universitaire F. Bourguiba
City
Monastir
ZIP/Postal Code
5000
Country
Tunisia

12. IPD Sharing Statement

Citations:
PubMed Identifier
21471564
Citation
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Combination Chemotherapy Compared With No Treatment Following Surgery in Treating Patients With Non-small Cell Lung Cancer

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