Chemotherapy and Radiation Therapy in Treating Patients With Stomach Cancer
Gastric Cancer
About this trial
This is an interventional treatment trial for Gastric Cancer focused on measuring stage I gastric cancer, stage II gastric cancer, stage III gastric cancer, stage IV gastric cancer, adenocarcinoma of the stomach
Eligibility Criteria
DISEASE CHARACTERISTICS: Histologically proven adenocarcinoma of the stomach Stage IB, II, IIIA, IIIB, and IV (T2-3, any N, M0) No lymph node metastases outside the field of resection (e.g., supraclavicular, mediastinal, or paraaortic nodes) Potentially resectable May involve the gastroesophageal junction, but bulk of tumor must be in the stomach No distant metastases No pleural or pericardial effusion No peritoneal disease diagnosed by laparoscopy PATIENT CHARACTERISTICS: Age: Not specified Performance status: Zubrod 0-2 Life expectancy: At least 16 weeks Hematopoietic: Absolute granulocyte count greater than 2,000/mm^3 Platelet count greater than 100,000/mm^3 Hepatic: Bilirubin no greater than 1.5 mg/dL Renal: Creatinine less than 1.5 mg/dL Cardiovascular: No New York Heart Association class III or IV heart disease No hypertension Neurologic: No cerebrovascular disease No diabetic neuropathy No mental status abnormalities Other: No uncontrolled diabetes No infection No other malignancies within past 5 years except resected squamous cell or basal cell skin cancer Not pregnant or nursing Fertile patients must use effective contraception PRIOR CONCURRENT THERAPY: Biologic therapy: No prior immunotherapy Chemotherapy: No prior chemotherapy Endocrine therapy: Not specified Radiotherapy: No prior radiotherapy to stomach Surgery: No prior surgery to stomach
Sites / Locations
- Providence Alaska Medical Center
- Foundation for Cancer Research and Education
- Mount Diablo Medical Center
- Northridge Hospital Medical Center
- University of California Davis Cancer Center
- Penrose - St. Francis Health Services
- St. Joseph Hospital
- Presbyterian-St Luke's Medical Center
- Rose Medical Center
- CCOP - Colorado Cancer Research Program, Incorporated
- Swedish Medical Center
- St. Mary's Regional Cancer Center at St. Mary's Hospital and Medical Center
- CCOP - Atlanta Regional
- Lutheran General Hospital Cancer Care Center
- Indiana University Cancer Center
- Veterans Affairs Medical Center - Indianapolis (Roudebush)
- Ball Memorial Hospital Cancer Center
- Porter Memorial Hospital
- Wendt Regional Cancer Center of Finley Hospital
- McLaren Regional Cancer Center
- Ellis Fischel Cancer Center at University of Missouri - Columbia
- CCOP - Kansas City
- Methodist Hospital Cancer Center at Nebraska Methodist Hospital - Omaha
- Norris Cotton Cancer Center at Dartmouth Medical School
- Monmouth Medical Center
- Fox Chase Virtua Health Cancer Program at Virtua Memorial Hospital
- Fox Chase Cancer Center at St. Francis Medical Center
- CCOP - Syracuse Hematology-Oncology Associates of Central New York, P.C.
- Presbyterian Hospital
- Wayne Memorial Hospital, Inc.
- Leo W. Jenkins Cancer Center of University Health Systems of Eastern Carolina
- Ireland Cancer Center
- CCOP - Dayton
- CCOP - Toledo Community Hospital
- St. Luke's Hospital Cancer Center
- Bryn Mawr Hospital
- Mercy Fitzgerald Hospital
- Delaware County Memorial Hospital
- Paoli Memorial Hospital
- Albert Einstein Cancer Center
- Western Pennsylvania Hospital
- CCOP - MainLine Health
- Lankenau Cancer Center at Lankenau Hospital
- Greenville Hospital System
- CCOP - Greenville
- CCOP - Upstate Carolina
- Rapid City Regional Hospital
- Harrington Cancer Center
- University of Texas - MD Anderson Cancer Center
- McKay-Dee Hospital Center
- Utah Valley Regional Medical Center - Provo
- LDS Hospital
- University of Washington Medical Center
- CCOP - Marshfield Clinic Research Foundation
- Columbia Hospital