Study of Fluoxetine in Patients With Depersonalization Disorder

Inclusioin Criteria: Meets DSM-IV criteria for depersonalization disorder in the last month Exclusion Criteria: Prior or concurrent bio- or chemotherapy or Use of any of the following within 2 weeks prior to study entry: antipsychotics, anticonvulsants, stimulants, barbiturates, lithium, benzodiazepines, or antidepressants Use of MAO inhibitors or investigational drugs within 4 weeks prior to study entry History of fluoxetine use at a dose of 10 mg or more for at least 6 weeks duration Hematologic, hepatic, renal, cardiovascular, pulmonary, metabolic, endocrine, systemic, or gastrointestinal disease History of mental disorders Current substance abuse Current eating disorder Current clinically unstable suicidal ideation Unstable medical illness Clinically unstable Clinically important abnormalities in lab tests or physical exams History of seizure disorders or abnormal electroencephalogram Hypersensitivity or severe side effects to fluoxetine Pregnancy or breast-feeding. Women of child-bearing potential must use effective contraception