Randomized Placebo-Controlled Study of Aerobic Exercise and Resistance Training Plus Megestrol Acetate for HIV-Wasting
Acquired Immunodeficiency Syndrome, HIV Wasting Syndrome, HIV Infections
About this trial
This is an interventional treatment trial for Acquired Immunodeficiency Syndrome focused on measuring disease-related problem/condition, human immunodeficiency virus infection, immunologic disorders and infectious disorders, nutrition, rare disease, viral infection
Eligibility Criteria
PROTOCOL ENTRY CRITERIA: --Disease Characteristics-- Human immunodeficiency virus seropositive with acquired immune deficiency syndrome Documented weight loss 5% to 15% below ideal weight --Prior/Concurrent Therapy-- No concurrent appetite stimulants At least 6 weeks since initiation of new antiretroviral therapy --Patient Characteristics-- Performance status: Karnofsky 70%-100% Hepatic: No ascites Renal: No nephrosis Other: No acute or untreated infection within 4 weeks prior to entry No hospitalization within 2 weeks prior to entry No gonadal insufficiency No edema No pleural effusion No uncontrolled diarrhea No physical or functional obstruction to food intake No physical handicap that would prevent resistance or aerobic exercise No cardiac abnormality that would render aerobic exercise a health risk No concurrent regular exercise of 3 or more hours a week No mental incompetence