Altered Calcium and Vitamin D in PMDD or Severe PMS
Premenstrual Syndrome
About this trial
This is an interventional diagnostic trial for Premenstrual Syndrome focused on measuring Premenstrual Dysphoric Disorder, Severe Premenstrual Syndrome, Calcium metabolism, Vitamin D, Bone Markers, Premenopausal, Menstrual Cycle
Eligibility Criteria
Inclusion Criteria: Medical history of severe PMS for the PMS group No medical history of PMS for the control group Prospective 2 month documentation of moderate to severe symptoms for the PMS group Prospective 2 month documentation of absent symptoms for the control group General good health Regular menstrual cycles No history of metabolic bone disease Exclusion Criteria: Amenorrhea Anorexia nervosa Malabsorption Inflammatory bowel disease Erosive gastrointestinal disease Gastrectomy Malignancy Multiple myeloma Primary hyperparathyroidism Use of suppressive doses of thyroxine Cushing's syndrome Use of glucocorticoids or anticonvulsants Use of diuretics Metabolic bone disease Pregnancy or perimenopause or menopause Mental retardation Menstrual irregularity Significant gynecologic abnormality Use of birth control pills
Sites / Locations
- St. Luke's-Roosevelt Hospital