The Safety and Effectiveness of (+)-Calanolide A in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs
HIV Infections
About this trial
This is an interventional treatment trial for HIV Infections focused on measuring CD4 Lymphocyte Count, Biological Markers, Anti-HIV Agents, Viral Load, Pharmacokinetics, calanolide A
Eligibility Criteria
Inclusion Criteria Patients may be eligible for this study if they: Are at least 18 years old. Agree to use effective methods of birth control during the study. Have a CD4 cell count of 200 cells/mm3 or more. Have HIV levels of 5000 copies/ml or more. Exclusion Criteria Patients will not be eligible for this study if they: Have abnormal blood tests. Have had a reaction to study medication. Have a history of opportunistic (AIDS-related) infection or cancer. Are being treated for active pulmonary tuberculosis. Have a fever of 39 degrees C or more within 14 days of beginning study treatment. Are unable to take medications by mouth. Have an abnormal chest X-ray or ECG within 30 days of beginning study treatment. Have hepatitis, hemophilia, or other blood disorder. Have significant heart, stomach, intestinal, liver, nerve, or kidney problems. Have a condition which may affect ability to participate in this study, such as drug or alcohol abuse or a serious mental disorder. Have taken anti-HIV drugs in the past. Are taking certain medications. Have had a blood transfusion within the 3 months prior to entering the study. Have had radiation or chemotherapy within 16 days before the screening visit or plan to receive such treatment during the study. Are pregnant or breast-feeding.
Sites / Locations
- South Florida Bioavailability Clinic
- Chicago Ctr for Clinical Research
- The CORE Ctr
- Anderson Clinical Research
- Anderson Clinical Research
- Burnside Clinic
- Univ of Texas Med Branch