Laparoscopy to Remove Pancreatic Tumors (Insulinomas)
Insulinoma
About this trial
This is an interventional trial for Insulinoma focused on measuring Islet Cell Tumors, Surgery, Ultrasound, Insulin, Rapid Assay, Arteriogram, Pancreas, Laparoscopy, Insulinoma, Localization, Hypoglycemia
Eligibility Criteria
INCLUSION CRITERIA: Patients with a history of symptomatic hypoglycemia due to insulin or proinsulin secretion presumed to be from an insulinoma. Age greater than or equal to 11 years. Patients must be willing to return to NIH for follow-up. Patients (or their parents or guardians) must be able to sign informed consent. EXCLUSION CRITERIA: Patients with a history of Multiple Endocrine Neoplasia type 1 (MEN1) or Von-Hipple-Lindau (VHL) syndrome or any history of a familial neuroendocrine tumor syndrome. pregnancy or breast-feeding. A negative pregnancy test (urine or serum) is required prior to enrollment. Known allergy to contrast agents and contraindications to or failure of pretreatment with prednisone, diphenhydramine, and cimetidine per standard procedure to prevent such reactions. Evidence of metastatic disease by CT, MRI or US. Platelet count less than 50,000. Medical condition which would preclude surgery including moderate to severe chronic lung disease that may be worsened by gas insufflation of the abdomen.
Sites / Locations
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)