Monoclonal Antibody Therapy and/or Vaccine Therapy in Treating Patients With Locally Advanced or Metastatic Colorectal Cancer
Colorectal Cancer
About this trial
This is an interventional treatment trial for Colorectal Cancer focused on measuring stage II colon cancer, stage III colon cancer, stage IV colon cancer, stage II rectal cancer, stage III rectal cancer, stage IV rectal cancer, adenocarcinoma of the colon, adenocarcinoma of the rectum
Eligibility Criteria
DISEASE CHARACTERISTICS: Histologically or cytologically confirmed locally advanced or metastatic adenocarcinoma of the colon or rectum Not amenable to curative surgery and either refractory to or inappropriate for chemotherapy Patient must have received adequate or appropriate prior chemotherapy for metastatic disease PATIENT CHARACTERISTICS: Age: 18 and over Performance status: Karnofsky 60-100% Life expectancy: At least 3 months Hematopoietic: Not specified Hepatic: Not specified Renal: Not specified Other: No other prior malignancy within the past 5 years except adequately treated basal cell carcinoma of the skin or carcinoma in situ No history of immunodeficiency No concurrent unstable medical condition that would preclude study No psychological, familial, sociological, or geographical condition that would preclude study compliance PRIOR CONCURRENT THERAPY: Biologic therapy: At least 1 month since prior immunomodulatory drugs Chemotherapy: See Disease Characteristics At least 4 weeks since prior chemotherapy No concurrent chemotherapy Endocrine therapy: At least 1 month since prior corticosteroids No concurrent corticosteroids Radiotherapy: At least 6 weeks since prior radiotherapy Surgery: See Disease Characteristics Other: At least 4 weeks since other prior anticancer drug No other concurrent investigational anticancer agent
Sites / Locations
- St. George's Hospital