Chemotherapy in Treating Patients With Locally Advanced or Metastatic Cancer of the Pancreas or Bile Duct
Extrahepatic Bile Duct Cancer, Pancreatic Cancer
About this trial
This is an interventional treatment trial for Extrahepatic Bile Duct Cancer focused on measuring stage II pancreatic cancer, stage III pancreatic cancer, unresectable extrahepatic bile duct cancer, adenocarcinoma of the extrahepatic bile duct, adenocarcinoma of the pancreas, stage IV pancreatic cancer
Eligibility Criteria
DISEASE CHARACTERISTICS: Histologically confirmed pancreatic or biliary duct adenocarcinoma Metastatic or locally advanced No cerebral metastasis Surgically unresectable PATIENT CHARACTERISTICS: Age: 18 to 75 Performance status: ECOG 0-2 Life expectancy: More than 12 months Hematopoietic: Absolute neutrophil count greater than 1,500/mm3 Platelet count greater than 100,000/mm3 Hepatic: Alkaline phosphatase less than 5 times normal Bilirubin less than 1.5 times normal Renal: Creatinine less than 1.5 times normal No uncontrolled or persistent hypercalcemia Cardiovascular: No severe cardiac failure Pulmonary: No severe respiratory failure Other: No other malignant tumor considered incurable or untreatable No uncontrolled pain No psychological, familial, social, or geographical reasons that would preclude study PRIOR CONCURRENT THERAPY: Biologic therapy: Not specified Chemotherapy: No prior chemotherapy Endocrine therapy: No concurrent corticosteroids except as antiemetic Radiotherapy: No prior radiotherapy Surgery: See Disease Characteristics
Sites / Locations
- Clinique De Rochebelle
- Centre Hospitalier Victor Dupouy
- Centre D'Oncologie Du Pays-Basqu
- C.H.G. Beauvais
- Institut Bergonie
- CMC Bligny
- Clinique Saint-Jean
- Hopital Fontenoy
- Hopital Beaujon
- Hopital Drevon
- Centre D'Oncologie Dunkerquois
- Polyclinique De La Foret
- CHR de Grenoble - La Tronche
- Centre De Charlebourg
- Clinique Du Cap D'OR
- Hopital Andre Mignot
- Hopital de la Croix Rousse
- Assistance Publique Hopitaux de Marseille Hopitaux Sud
- Hopital Notre-Dame de Bon Secours
- Hopital Clinique Claude Bernard
- Intercommunal Hospital
- Centre Hospitalier De Moulins Yzeure
- Centre Hospitalier de Mulhouse
- CHR Hotel Dieu
- American Hospital of Paris
- CHR D'Orleans - Hopital de la Source
- Hopital Boucicaut
- Hopital Laennec
- Clinique Du Mont Louis
- Hopital Rothschild
- Hopital Saint Joseph
- L'Institut Mutualiste Montsouris Jourdan
- Hopital Saint-Louis
- Hopital Saint Antoine
- Hopital Tenon
- Hopital De La Croix
- Clinique Bizet
- Hopital Haut Leveque
- Clinique Ste-Marie
- Hopital Claude Gallien
- Polyclinique De Courlancy
- Oncologie Medicale
- Centre du Rouget
- C.H. Senlis
- Centre Hospitalier Intercommunal Toulon - La Seyne/Mer
- Clinique Pasteur
- Polyclinique Flemming
- Centre Saint-Yves
- Institut Gustave Roussy
- Hopital de la Ville D'Esch-sur-Alzette