Motor Learning in Stroke Patients and Healthy Volunteers
Stroke, Healthy
About this trial
This is an observational trial for Stroke focused on measuring Stroke, Learning, Plasticity, Motor, Rehabilitation, Premotor, Normal Control, Healthy Volunteer, HV, Motor Learning
Eligibility Criteria
INCLUSION CRITERIA FOR HEALTHY VOLUNTEERS Age: 18 years to 100 years Normal physical and neurological examinations EXCLUSION CRITERIA FOR HEALTHY VOLUNTEERS Contraindications for transcranial magnetic stimulation: pacemaker, implanted medical pump, metal plate in skull, metal objects inside the eye or skull, history of seizures INCLUSION CRITERIA FOR STROKE PATIENTS Age: 18 years to 100 years Single ischemic or hemorrhagic hemispheric stroke at least one year before enrollment in study, confirmed by neuroimaging studies (computerized tomography or magnetic resonance imaging). Ability to perform the Jebsen-Taylor test. EXCLUSION CRITERIA FOR STROKE PATIENTS More than one stroke. Other brain lesions (i.e., traumatic brain injury, brain tumor) or neurological problems (i.e., multiple sclerosis, dementia, Parkinson's disease) Depression or poor motivational capacity Serious cognitive deficits (defined as equivalent to a mini-mental state exam score of 20 or less). Inability to understand instructions for the Jebsen-Taylor test. Uncontrolled medical problems including cardiovascular disease, severe rheumatoid arthritis, active joint deformity of arthritic origin, active cancer or renal disease, any kind of end-stage pulmonary or cardiovascular disease, uncontrolled epilepsy Contraindications for transcranial magnetic stimulation: pacemaker, implanted medical pump, metal plate in skull, metal objects inside the eye or skull, history of seizures
Sites / Locations
- National Institute of Neurological Disorders and Stroke (NINDS)