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Cisplatin Plus Gemcitabine With or Without Paclitaxel in Treating Patients With Stage IV Urinary Tract Cancer

Primary Purpose

Bladder Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter, Urethral Cancer

Status
Completed
Phase
Phase 3
Locations
International
Study Type
Interventional
Intervention
cisplatin
gemcitabine hydrochloride
paclitaxel
Sponsored by
European Organisation for Research and Treatment of Cancer - EORTC
About
Eligibility
Locations
Outcomes
Full info

About this trial

This is an interventional treatment trial for Bladder Cancer focused on measuring stage IV bladder cancer, transitional cell carcinoma of the bladder, urethral cancer associated with invasive bladder cancer, metastatic transitional cell cancer of the renal pelvis and ureter, regional transitional cell cancer of the renal pelvis and ureter

Eligibility Criteria

18 Years - undefined (Adult, Older Adult)All SexesDoes not accept healthy volunteers

DISEASE CHARACTERISTICS: Histologically confirmed stage IV transitional cell carcinoma of the urothelium (pure or mixed) including bladder, urethra, ureter, and renal pelvis T4b, any N OR any T, N2-3 OR M1 Ineligible for surgery or radiotherapy with curative intent Measurable or evaluable disease No known CNS metastases PATIENT CHARACTERISTICS: Age: 18 and over Performance status: WHO 0-1 Life expectancy: At least 12 weeks Hematopoietic: WBC at least 3,000/mm^3 Platelet count at least 100,000/mm^3 Hemoglobin at least 10 g/dL Hepatic: Bilirubin less than 1.25 times normal AST or ALT less than 2.5 times normal Renal: Glomerular filtration rate at least 60 mL/min Calcium normal or clinically insignificant Cardiovascular: No clinically significant cardiac arrhythmia No congestive heart failure No complete bundle branch block No New York Heart Association class III or IV heart disease Other: Not pregnant or nursing Negative pregnancy test Fertile patients must use effective contraception during and for 6 months after study participation No psychological, familial, sociological, or geographical condition that would preclude study compliance No grade 3 or 4 infection without neutropenia No other serious concurrent systemic disorder that would preclude study therapy No mental disorder that would preclude study compliance No grade II or greater neuropathy No other prior or concurrent malignancy except appropriately treated carcinoma in situ of the cervix, basal cell carcinoma of the skin, or incidental prostate cancer (T1, Gleason score no greater than 6, and PSA less than 0.5 ng/mL) PRIOR CONCURRENT THERAPY: Biologic therapy: No prior investigational biologic agents (e.g., antiangiogenic products, signal transduction pathway inhibitors, immunomodulators, or monoclonal antibody therapy) At least 4 weeks since prior immunotherapy Chemotherapy: No prior systemic chemotherapy At least 4 weeks since prior local intravesical chemotherapy Endocrine therapy: Not specified Radiotherapy: See Disease Characteristics No more than 1 prior course of radiotherapy At least 4 weeks since prior radiotherapy and recovered Surgery: See Disease Characteristics Prior urological procedures to relieve urinary tract obstruction and improve renal function allowed (e.g., ureteral stent or percutaneous nephrostomy)

Sites / Locations

  • Veterans Affairs Medical Center - Tucson
  • Arizona Cancer Center at University of Arizona Health Sciences Center
  • Veterans Affairs Medical Center - Little Rock (McClellan)
  • City of Hope Comprehensive Cancer Center
  • USC/Norris Comprehensive Cancer Center and Hospital
  • Jonsson Comprehensive Cancer Center, UCLA
  • Veterans Affairs Outpatient Clinic - Martinez
  • Chao Family Comprehensive Cancer Center at University of California Irvine Cancer Center
  • University of California Davis Cancer Center
  • University of Colorado Cancer Center at University of Colorado Health Sciences Center
  • Veterans Affairs Medical Center - Hines (Hines Junior VA Hospital)
  • Cardinal Bernardin Cancer Center at Loyola University Medical Center
  • Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center
  • Veterans Affairs Medical Center - Lexington
  • Markey Cancer Center at University of Kentucky Chandler Medical Center
  • Tulane University School of Medicine
  • Veterans Affairs Medical Center - New Orleans
  • Louisiana State University Health Sciences Center - Shreveport
  • Veterans Affairs Medical Center - Shreveport
  • Cancer Research Center at Boston Medical Center
  • Veterans Affairs Medical Center - Ann Arbor
  • University of Michigan Comprehensive Cancer Center
  • Barbara Ann Karmanos Cancer Institute
  • Josephine Ford Cancer Center at Henry Ford Hospital
  • Providence Cancer Institute at Providence Hospital
  • St. Mary's - Duluth Clinic Cancer Center
  • Veterans Affairs Medical Center - Biloxi
  • University of Mississippi Medical Center
  • Veterans Affairs Medical Center - Jackson
  • Veterans Affairs Medical Center - Kansas City
  • CCOP - Kansas City
  • St. Louis University Hospital Cancer Center
  • Herbert Irving Comprehensive Cancer Center at Columbia University
  • James P. Wilmot Cancer Center at University of Rochester Medical Center
  • Veterans Affairs Medical Center - Cincinnati
  • Charles M. Barrett Cancer Center at University Hospital
  • Cleveland Clinic Taussig Cancer Center
  • Oklahoma University Medical Center at University of Oklahoma Health Sciences Center
  • Veterans Affairs Medical Center - Oklahoma City
  • Cancer Institute at Oregon Health and Science University
  • Veterans Affairs Medical Center - Portland
  • Veterans Affairs Medical Center - Charleston
  • Hollings Cancer Center at Medical University of South Carolina
  • University of Tennessee Cancer Institute
  • Veterans Affairs Medical Center - Memphis
  • Harrington Cancer Center
  • Veterans Affairs Medical Center - Amarillo
  • Arkansas Cancer Research Center at University of Arkansas for Medical Sciences
  • Brooke Army Medical Center
  • University of Texas Medical Branch
  • University of Texas - MD Anderson Cancer Center
  • Southwest Cancer and Research Center at University Medical Center
  • University of Texas Health Science Center at San Antonio
  • Veterans Affairs Medical Center - San Antonio (Murphy)
  • Huntsman Cancer Institute
  • Veterans Affairs Medical Center - Salt Lake City
  • Swedish Cancer Institute at Swedish Medical Center - First Hill Campus
  • Veterans Affairs Medical Center - Seattle
  • Fremantle Hospital
  • Kaiser Franz Josef Hospital
  • Onze Lieve Vrouw Ziekenhuis Aalst
  • Institut Jules Bordet
  • Academisch Ziekenhuis der Vrije Universiteit Brussel
  • Universitair Ziekenhuis Antwerpen
  • CHU Liege - Domaine Universitaire du Sart Tilman
  • Tom Baker Cancer Center - Calgary
  • Cross Cancer Institute
  • Lethbridge Cancer Clinic
  • British Columbia Cancer Agency - Centre for the Southern Interior
  • Nanaimo Cancer Clinic at Nanaimo Regional General Hospital
  • Lions Gate Hospital
  • Prostate Centre at Vancouver General Hospital
  • British Columbia Cancer Agency
  • Providence Health Care - Vancouver
  • British Columbia Cancer Agency - Vancouver Island Cancer Centre
  • G. Steinhoff Clinical Research
  • CancerCare Manitoba
  • Moncton Hospital
  • Doctor Leon Richard Oncology Centre
  • Saint John Regional Hospital
  • Newfoundland Cancer Treatment and Research Foundation
  • Nova Scotia Cancer Centre
  • Cape Breton Cancer Centre
  • Royal Victoria Hospital, Barrie
  • William Osler Health Centre
  • Hamilton and District Urology Association
  • Margaret and Charles Juravinski Cancer Centre
  • Kingston Regional Cancer Centre
  • Grand River Regional Cancer Centre
  • London Health Sciences Centre
  • Cancer Care Ontario-London Regional Cancer Centre
  • Markham Stouffville Hospital
  • Trillium Health Centre
  • Credit Valley Hospital
  • Southlake Regional Health Centre
  • North York General Hospital, Ontario
  • Sunnybrook and Women's College Health Sciences Centre
  • Male Health Centre - Oakville
  • Durham Regional Cancer Centre at Lakeridge Health Oshawa
  • Ottawa Regional Cancer Centre
  • Peterborough Oncology Clinic
  • Algoma Reginal Cancer Program at Sault Area Hospital
  • Scarborough Hospital - General Site
  • Hotel Dieu Health Sciences Hospital - Niagara
  • Northeastern Ontario Regional Cancer Centre - Sudbury
  • Northwestern Ontario Regional Cancer Care
  • Toronto East General Hospital
  • Toronto Sunnybrook Regional Cancer Centre
  • St. Michael's Hospital - Toronto
  • Mount Sinai Hospital - Toronto
  • Toronto General Hospital
  • Princess Margaret Hospital
  • Male Health Centre - North York
  • St. Joseph's Health Centre - Toronto
  • Humber River Regional Hospital - Weston
  • Cancer Care Ontario - Windsor Regional Cancer Centre
  • Prince Edward Island Cancer Center at Queen Elizabeth Hospital
  • Complexe Hospitalier de la Sagamie
  • CHUS-Hopital Fleurimont
  • Hopital Charles Lemoyne
  • Centre Hospitalier Regional de Lanaudiere
  • Hotel-Dieu de Levis
  • Maisonneuve-Rosemont Hospital
  • Centre Hospitalier de l'Universite de Montreal
  • McGill University
  • Hotel Dieu de Montreal
  • Hopital Sainte Justine
  • Hopital Du Sacre-Coeur de Montreal
  • Centre Hospitalier Universitaire de Quebec
  • Hopital du Saint-Sacrement, Quebec
  • L'Hopital Laval
  • Allan Blair Cancer Centre
  • Saskatoon Cancer Centre
  • Centre Hospitalier Regional de Rimouski
  • Aarhus Kommunehospital
  • Rigshospitalet
  • Centre Paul Papin
  • Institut Bergonie
  • Centre Hospitalier Docteur Duchenne
  • Centre Regional Francois Baclesse
  • Centre Hospitalier Universitaire Henri Mondor
  • Centre de Lutte Contre le Cancer, Georges-Francois Leclerc
  • CHU de Grenoble - Hopital de la Tronche
  • Centre Hospitalier Departemental
  • Centre Oscar Lambret
  • Centre Leon Berard
  • CHU de la Timone
  • Hopital Lapeyronie-CHU Montpellier
  • Centre Regional de Lutte Contre le Cancer - Centre Val d'Aurelle
  • Centre Regional Rene Gauducheau
  • Hopital Europeen Georges Pompidou
  • Institut Curie - Section Medicale
  • Hopital Tenon
  • Centre Eugene Marquis
  • Centre Henri Becquerel
  • Centre Rene Huguenin
  • Centre Medico-Chirurgical Foch
  • Centre Antoine Lacassagne
  • Institut Claudius Regaud
  • Centre Alexis Vautrin
  • Krankenhaus Hohe Warte Mediziniche Klinik
  • Charite Humboldt - University Berlin
  • Charite - Universitaetsmedizin Berlin - Campus Benjamin Franklin
  • Helios - Klinik Blankenhain
  • Universitaetsklinikum Bonn
  • Staedtische Kliniken Dortmund
  • Universitaetsklinik Duesseldorf
  • St. Markus Krankenhaus
  • Klinikum der J.W. Goethe Universitaet
  • Klinikum Fulda
  • Martin Luther Universitaet
  • Marienkrankenhaus
  • Universitat des Saarlandes Innere Medizin 1
  • Klinikum der Friedrich-Schiller Universitaet Jena
  • Klinikum der Stadt Ludwigshafen am Rhein
  • Staedtisches Krankenhaus Sued
  • Medizinische Universitaet Luebeck
  • Kreiskrankenhaus Luedenscheid
  • Klinikum der Stadt Mannheim
  • University of Marburg
  • Klinik und Poliklinik fuer Kinderheilkunde
  • Klinikum Rechts Der Isar - Technische Universitaet Muenchen
  • Klinikum Neubrandenburg
  • Klinikum Nuernberg - Klinikum Nord
  • Paracelsus Karankenhaus Ruit
  • Asklepios Klinik Pasewalk
  • Diakonie - Krankenhaus
  • Johanniter Kankenhaus Stendal
  • Katharinenhospital
  • Universitaetsklinikum Tuebingen
  • Universitaet Ulm
  • Klinikum der Stadt Wolfsburg
  • Klinikum St. Marien
  • Witten University - Klinikum Wuppertal
  • National Institute of Oncology
  • Rabin Medical Center - Beilinson Campus
  • Assaf Harofeh Medical Center
  • Ospedale Santa Croce
  • Istituto Scientifico H.San Raffaele
  • Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital
  • Jeroen Bosch Ziekenhuis
  • Daniel Den Hoed Cancer Center at Erasmus Medical Center
  • Academisch Ziekenhuis Utrecht
  • University Hospital - Rotterdam Dijkzigt
  • Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology
  • National Cancer Institute - Bratislava
  • Hospital Universitari Germans Trias i Pujol
  • Hospital Del Mar
  • Hospital Clinic y Provincial de Barcelona
  • Hospital General Universitari Vall d'Hebron
  • Hospital Juan Canalejo
  • Hospital General Universitario De Guadalajara
  • Hospital Cuidad de Jaen
  • Hospital Arquitecto Marcide
  • Hospital Universitario San Carlos
  • Hospital Universitario 12 de Octubre
  • Hospital Clinico Universitario - Malaga
  • Hospital Son Dureta
  • Hospsital de Sabadell
  • Hospital Universitario Marques de Valdecilla
  • Hospital Consorci Sanitari De Terrassa
  • Instituto Valenciano De Oncologia
  • Hospital Clinico Universitario de Valencia
  • Hospital Rio Hortega
  • Hospital General De Vic
  • Hospital Clinico Universitario
  • Princess Royal Hospital
  • St. James's University Hospital
  • Saint Bartholomew's Hospital
  • Guy's and St. Thomas' Hospitals NHS Trust
  • Northern Centre for Cancer Treatment at Newcastle General Hospital
  • Royal South Hants Hospital
  • Royal Marsden Hospital - Sutton
  • Velindre Cancer Center at Velinde Hospital

Outcomes

Primary Outcome Measures

Secondary Outcome Measures

Full Information

First Posted
August 10, 2001
Last Updated
June 11, 2013
Sponsor
European Organisation for Research and Treatment of Cancer - EORTC
Collaborators
National Cancer Institute (NCI), Groupe D'Etude des Tumeurs Uro-Genitales, Institute of Cancer Research, United Kingdom, Central European Cooperative Oncology Group, NCIC Clinical Trials Group, SWOG Cancer Research Network, German Association of Urologic Oncology, Spanish Oncology Genito-Urinary Group, Medical Research Council
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1. Study Identification

Unique Protocol Identification Number
NCT00022191
Brief Title
Cisplatin Plus Gemcitabine With or Without Paclitaxel in Treating Patients With Stage IV Urinary Tract Cancer
Official Title
Randomized Phase III Study Comparing Paclitaxel/Cisplatin/Gemcitabine and Cisplatin/Gemcitabine in Patients With Metastatic or Locally Advanced Urothelial Cancer Without Prior Systemic Therapy
Study Type
Interventional

2. Study Status

Record Verification Date
June 2013
Overall Recruitment Status
Completed
Study Start Date
May 2001 (undefined)
Primary Completion Date
June 2004 (Actual)
Study Completion Date
undefined (undefined)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
European Organisation for Research and Treatment of Cancer - EORTC
Collaborators
National Cancer Institute (NCI), Groupe D'Etude des Tumeurs Uro-Genitales, Institute of Cancer Research, United Kingdom, Central European Cooperative Oncology Group, NCIC Clinical Trials Group, SWOG Cancer Research Network, German Association of Urologic Oncology, Spanish Oncology Genito-Urinary Group, Medical Research Council

4. Oversight

5. Study Description

Brief Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known which combination chemotherapy regimen is more effective for urinary tract cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of cisplatin plus gemcitabine with or without paclitaxel in treating patients who have stage IV urinary tract cancer.
Detailed Description
OBJECTIVES: Compare the duration of survival of patients with stage IV transitional cell carcinoma of the urothelium treated with cisplatin and gemcitabine with or without paclitaxel. Compare the duration of progression-free survival, response rates, and duration of response in patients treated with these regimens. Compare the toxicity of these regimens in these patients. OUTLINE: This is a randomized, open-label, multicenter study. Patients are stratified according to participating center, WHO performance status (0 vs 1), and presence of metastatic disease (yes vs no). Patients are randomized to one of two treatment arms. Arm I: Patients receive gemcitabine IV over 30 minutes on days 1, 8, and 15 and cisplatin IV over 1 hour on day 1 or 2. Treatment repeats every 28 days for a maximum of 6 courses in the absence of disease progression or unacceptable toxicity. Arm II: Patients receive paclitaxel IV over 1 hour on days 1 and 8 followed by cisplatin IV over 1 hour on day 1 and gemcitabine IV over 30 minutes on days 1 and 8. Treatment repeats every 21 days for a maximum of 6 courses in the absence of disease progression or unacceptable toxicity. Patients are followed every 3 months for 2 years and then every 6 months for at least 3 years. Peer Reviewed and Funded or Endorsed by Cancer Research UK PROJECTED ACCRUAL: A total of 610 patients (305 per treatment arm) will be accrued for this study within 3.04 years.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Bladder Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter, Urethral Cancer
Keywords
stage IV bladder cancer, transitional cell carcinoma of the bladder, urethral cancer associated with invasive bladder cancer, metastatic transitional cell cancer of the renal pelvis and ureter, regional transitional cell cancer of the renal pelvis and ureter

7. Study Design

Primary Purpose
Treatment
Study Phase
Phase 3
Masking
None (Open Label)
Allocation
Randomized
Enrollment
608 (Actual)

8. Arms, Groups, and Interventions

Intervention Type
Drug
Intervention Name(s)
cisplatin
Intervention Type
Drug
Intervention Name(s)
gemcitabine hydrochloride
Intervention Type
Drug
Intervention Name(s)
paclitaxel

10. Eligibility

Sex
All
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
DISEASE CHARACTERISTICS: Histologically confirmed stage IV transitional cell carcinoma of the urothelium (pure or mixed) including bladder, urethra, ureter, and renal pelvis T4b, any N OR any T, N2-3 OR M1 Ineligible for surgery or radiotherapy with curative intent Measurable or evaluable disease No known CNS metastases PATIENT CHARACTERISTICS: Age: 18 and over Performance status: WHO 0-1 Life expectancy: At least 12 weeks Hematopoietic: WBC at least 3,000/mm^3 Platelet count at least 100,000/mm^3 Hemoglobin at least 10 g/dL Hepatic: Bilirubin less than 1.25 times normal AST or ALT less than 2.5 times normal Renal: Glomerular filtration rate at least 60 mL/min Calcium normal or clinically insignificant Cardiovascular: No clinically significant cardiac arrhythmia No congestive heart failure No complete bundle branch block No New York Heart Association class III or IV heart disease Other: Not pregnant or nursing Negative pregnancy test Fertile patients must use effective contraception during and for 6 months after study participation No psychological, familial, sociological, or geographical condition that would preclude study compliance No grade 3 or 4 infection without neutropenia No other serious concurrent systemic disorder that would preclude study therapy No mental disorder that would preclude study compliance No grade II or greater neuropathy No other prior or concurrent malignancy except appropriately treated carcinoma in situ of the cervix, basal cell carcinoma of the skin, or incidental prostate cancer (T1, Gleason score no greater than 6, and PSA less than 0.5 ng/mL) PRIOR CONCURRENT THERAPY: Biologic therapy: No prior investigational biologic agents (e.g., antiangiogenic products, signal transduction pathway inhibitors, immunomodulators, or monoclonal antibody therapy) At least 4 weeks since prior immunotherapy Chemotherapy: No prior systemic chemotherapy At least 4 weeks since prior local intravesical chemotherapy Endocrine therapy: Not specified Radiotherapy: See Disease Characteristics No more than 1 prior course of radiotherapy At least 4 weeks since prior radiotherapy and recovered Surgery: See Disease Characteristics Prior urological procedures to relieve urinary tract obstruction and improve renal function allowed (e.g., ureteral stent or percutaneous nephrostomy)
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Joaquim Bellmunt, MD, PhD
Organizational Affiliation
Vall d'Hebron University Hospital
Official's Role
Study Chair
First Name & Middle Initial & Last Name & Degree
Stephane Culine, MD
Organizational Affiliation
Institut du Cancer de Montpellier - Val d'Aurelle
Official's Role
Study Chair
First Name & Middle Initial & Last Name & Degree
Michael Leahy, MBChB, FRACP, FRCP, FRC Path
Organizational Affiliation
Fremantle Hospital
Official's Role
Study Chair
First Name & Middle Initial & Last Name & Degree
Christoph Zielinski, MD
Organizational Affiliation
Allgemeines Krankenhaus - Universitatskliniken
Official's Role
Study Chair
First Name & Middle Initial & Last Name & Degree
Malcolm J. Moore, MD
Organizational Affiliation
Princess Margaret Hospital, Canada
Official's Role
Study Chair
First Name & Middle Initial & Last Name & Degree
David C. Smith, MD
Organizational Affiliation
University of Michigan Rogel Cancer Center
Official's Role
Study Chair
First Name & Middle Initial & Last Name & Degree
Andreas Boehle, MD
Organizational Affiliation
Universitaetsklinikum Schleswig-Holstein - Campus Luebeck
Official's Role
Study Chair
First Name & Middle Initial & Last Name & Degree
Jose Baselga, MD
Organizational Affiliation
Vall d'Hebron University Hospital
Official's Role
Study Chair
Facility Information:
Facility Name
Veterans Affairs Medical Center - Tucson
City
Tucson
State/Province
Arizona
ZIP/Postal Code
85723
Country
United States
Facility Name
Arizona Cancer Center at University of Arizona Health Sciences Center
City
Tucson
State/Province
Arizona
ZIP/Postal Code
85724
Country
United States
Facility Name
Veterans Affairs Medical Center - Little Rock (McClellan)
City
Little Rock
State/Province
Arkansas
ZIP/Postal Code
72205
Country
United States
Facility Name
City of Hope Comprehensive Cancer Center
City
Duarte
State/Province
California
ZIP/Postal Code
91010-3000
Country
United States
Facility Name
USC/Norris Comprehensive Cancer Center and Hospital
City
Los Angeles
State/Province
California
ZIP/Postal Code
90033
Country
United States
Facility Name
Jonsson Comprehensive Cancer Center, UCLA
City
Los Angeles
State/Province
California
ZIP/Postal Code
90095-1781
Country
United States
Facility Name
Veterans Affairs Outpatient Clinic - Martinez
City
Martinez
State/Province
California
ZIP/Postal Code
94553
Country
United States
Facility Name
Chao Family Comprehensive Cancer Center at University of California Irvine Cancer Center
City
Orange
State/Province
California
ZIP/Postal Code
92868
Country
United States
Facility Name
University of California Davis Cancer Center
City
Sacramento
State/Province
California
ZIP/Postal Code
95817
Country
United States
Facility Name
University of Colorado Cancer Center at University of Colorado Health Sciences Center
City
Aurora
State/Province
Colorado
ZIP/Postal Code
80010
Country
United States
Facility Name
Veterans Affairs Medical Center - Hines (Hines Junior VA Hospital)
City
Hines
State/Province
Illinois
ZIP/Postal Code
60141
Country
United States
Facility Name
Cardinal Bernardin Cancer Center at Loyola University Medical Center
City
Maywood
State/Province
Illinois
ZIP/Postal Code
60153-5500
Country
United States
Facility Name
Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center
City
Kansas City
State/Province
Kansas
ZIP/Postal Code
66160-7390
Country
United States
Facility Name
Veterans Affairs Medical Center - Lexington
City
Lexington
State/Province
Kentucky
ZIP/Postal Code
40502-2236
Country
United States
Facility Name
Markey Cancer Center at University of Kentucky Chandler Medical Center
City
Lexington
State/Province
Kentucky
ZIP/Postal Code
40536-0084
Country
United States
Facility Name
Tulane University School of Medicine
City
New Orleans
State/Province
Louisiana
ZIP/Postal Code
70112
Country
United States
Facility Name
Veterans Affairs Medical Center - New Orleans
City
New Orleans
State/Province
Louisiana
ZIP/Postal Code
70112
Country
United States
Facility Name
Louisiana State University Health Sciences Center - Shreveport
City
Shreveport
State/Province
Louisiana
ZIP/Postal Code
71130-3932
Country
United States
Facility Name
Veterans Affairs Medical Center - Shreveport
City
Shreveport
State/Province
Louisiana
ZIP/Postal Code
71130
Country
United States
Facility Name
Cancer Research Center at Boston Medical Center
City
Boston
State/Province
Massachusetts
ZIP/Postal Code
02118
Country
United States
Facility Name
Veterans Affairs Medical Center - Ann Arbor
City
Ann Arbor
State/Province
Michigan
ZIP/Postal Code
48105
Country
United States
Facility Name
University of Michigan Comprehensive Cancer Center
City
Ann Arbor
State/Province
Michigan
ZIP/Postal Code
48109-0330
Country
United States
Facility Name
Barbara Ann Karmanos Cancer Institute
City
Detroit
State/Province
Michigan
ZIP/Postal Code
48201-1379
Country
United States
Facility Name
Josephine Ford Cancer Center at Henry Ford Hospital
City
Detroit
State/Province
Michigan
ZIP/Postal Code
48202
Country
United States
Facility Name
Providence Cancer Institute at Providence Hospital
City
Southfield
State/Province
Michigan
ZIP/Postal Code
48075
Country
United States
Facility Name
St. Mary's - Duluth Clinic Cancer Center
City
Duluth
State/Province
Minnesota
ZIP/Postal Code
55805
Country
United States
Facility Name
Veterans Affairs Medical Center - Biloxi
City
Biloxi
State/Province
Mississippi
ZIP/Postal Code
39531-2410
Country
United States
Facility Name
University of Mississippi Medical Center
City
Jackson
State/Province
Mississippi
ZIP/Postal Code
39216-4505
Country
United States
Facility Name
Veterans Affairs Medical Center - Jackson
City
Jackson
State/Province
Mississippi
ZIP/Postal Code
39216
Country
United States
Facility Name
Veterans Affairs Medical Center - Kansas City
City
Kansas City
State/Province
Missouri
ZIP/Postal Code
64128
Country
United States
Facility Name
CCOP - Kansas City
City
Kansas City
State/Province
Missouri
ZIP/Postal Code
64131
Country
United States
Facility Name
St. Louis University Hospital Cancer Center
City
Saint Louis
State/Province
Missouri
ZIP/Postal Code
63110
Country
United States
Facility Name
Herbert Irving Comprehensive Cancer Center at Columbia University
City
New York
State/Province
New York
ZIP/Postal Code
10032
Country
United States
Facility Name
James P. Wilmot Cancer Center at University of Rochester Medical Center
City
Rochester
State/Province
New York
ZIP/Postal Code
14642
Country
United States
Facility Name
Veterans Affairs Medical Center - Cincinnati
City
Cincinnati
State/Province
Ohio
ZIP/Postal Code
45220-2288
Country
United States
Facility Name
Charles M. Barrett Cancer Center at University Hospital
City
Cincinnati
State/Province
Ohio
ZIP/Postal Code
45267-0501
Country
United States
Facility Name
Cleveland Clinic Taussig Cancer Center
City
Cleveland
State/Province
Ohio
ZIP/Postal Code
44195-9001
Country
United States
Facility Name
Oklahoma University Medical Center at University of Oklahoma Health Sciences Center
City
Oklahoma City
State/Province
Oklahoma
ZIP/Postal Code
73104
Country
United States
Facility Name
Veterans Affairs Medical Center - Oklahoma City
City
Oklahoma City
State/Province
Oklahoma
ZIP/Postal Code
73104
Country
United States
Facility Name
Cancer Institute at Oregon Health and Science University
City
Portland
State/Province
Oregon
ZIP/Postal Code
97201-3098
Country
United States
Facility Name
Veterans Affairs Medical Center - Portland
City
Portland
State/Province
Oregon
ZIP/Postal Code
97207
Country
United States
Facility Name
Veterans Affairs Medical Center - Charleston
City
Charleston
State/Province
South Carolina
ZIP/Postal Code
29401-5799
Country
United States
Facility Name
Hollings Cancer Center at Medical University of South Carolina
City
Charleston
State/Province
South Carolina
ZIP/Postal Code
29425
Country
United States
Facility Name
University of Tennessee Cancer Institute
City
Memphis
State/Province
Tennessee
ZIP/Postal Code
38103
Country
United States
Facility Name
Veterans Affairs Medical Center - Memphis
City
Memphis
State/Province
Tennessee
ZIP/Postal Code
38104
Country
United States
Facility Name
Harrington Cancer Center
City
Amarillo
State/Province
Texas
ZIP/Postal Code
79106
Country
United States
Facility Name
Veterans Affairs Medical Center - Amarillo
City
Amarillo
State/Province
Texas
ZIP/Postal Code
79106
Country
United States
Facility Name
Arkansas Cancer Research Center at University of Arkansas for Medical Sciences
City
Del Rio
State/Province
Texas
ZIP/Postal Code
78840
Country
United States
Facility Name
Brooke Army Medical Center
City
Fort Sam Houston
State/Province
Texas
ZIP/Postal Code
78234-6200
Country
United States
Facility Name
University of Texas Medical Branch
City
Galveston
State/Province
Texas
ZIP/Postal Code
77555-0565
Country
United States
Facility Name
University of Texas - MD Anderson Cancer Center
City
Houston
State/Province
Texas
ZIP/Postal Code
77030-4095
Country
United States
Facility Name
Southwest Cancer and Research Center at University Medical Center
City
Lubbock
State/Province
Texas
ZIP/Postal Code
79415-3364
Country
United States
Facility Name
University of Texas Health Science Center at San Antonio
City
San Antonio
State/Province
Texas
ZIP/Postal Code
78229-3900
Country
United States
Facility Name
Veterans Affairs Medical Center - San Antonio (Murphy)
City
San Antonio
State/Province
Texas
ZIP/Postal Code
78229
Country
United States
Facility Name
Huntsman Cancer Institute
City
Salt Lake City
State/Province
Utah
ZIP/Postal Code
84112-5550
Country
United States
Facility Name
Veterans Affairs Medical Center - Salt Lake City
City
Salt Lake City
State/Province
Utah
ZIP/Postal Code
84148
Country
United States
Facility Name
Swedish Cancer Institute at Swedish Medical Center - First Hill Campus
City
Seattle
State/Province
Washington
ZIP/Postal Code
98104
Country
United States
Facility Name
Veterans Affairs Medical Center - Seattle
City
Seattle
State/Province
Washington
ZIP/Postal Code
98108
Country
United States
Facility Name
Fremantle Hospital
City
Fremantle
State/Province
Western Australia
ZIP/Postal Code
6160
Country
Australia
Facility Name
Kaiser Franz Josef Hospital
City
Vienna
ZIP/Postal Code
A-1100
Country
Austria
Facility Name
Onze Lieve Vrouw Ziekenhuis Aalst
City
Aalst
ZIP/Postal Code
B-9300
Country
Belgium
Facility Name
Institut Jules Bordet
City
Brussels
ZIP/Postal Code
1000
Country
Belgium
Facility Name
Academisch Ziekenhuis der Vrije Universiteit Brussel
City
Brussels
ZIP/Postal Code
1090
Country
Belgium
Facility Name
Universitair Ziekenhuis Antwerpen
City
Edegem
ZIP/Postal Code
B-2650
Country
Belgium
Facility Name
CHU Liege - Domaine Universitaire du Sart Tilman
City
Liege
ZIP/Postal Code
B-4000
Country
Belgium
Facility Name
Tom Baker Cancer Center - Calgary
City
Calgary
State/Province
Alberta
ZIP/Postal Code
T2N 4N2
Country
Canada
Facility Name
Cross Cancer Institute
City
Edmonton
State/Province
Alberta
ZIP/Postal Code
T6G 1Z2
Country
Canada
Facility Name
Lethbridge Cancer Clinic
City
Lethbridge
State/Province
Alberta
ZIP/Postal Code
T1J 1W5
Country
Canada
Facility Name
British Columbia Cancer Agency - Centre for the Southern Interior
City
Kelowna
State/Province
British Columbia
ZIP/Postal Code
V1Y 5L3
Country
Canada
Facility Name
Nanaimo Cancer Clinic at Nanaimo Regional General Hospital
City
Nanaimo
State/Province
British Columbia
ZIP/Postal Code
V9S 2B7
Country
Canada
Facility Name
Lions Gate Hospital
City
North Vancouver
State/Province
British Columbia
ZIP/Postal Code
V7L 2P9
Country
Canada
Facility Name
Prostate Centre at Vancouver General Hospital
City
Vancouver
State/Province
British Columbia
ZIP/Postal Code
V5Z 3J5
Country
Canada
Facility Name
British Columbia Cancer Agency
City
Vancouver
State/Province
British Columbia
ZIP/Postal Code
V5Z 4E6
Country
Canada
Facility Name
Providence Health Care - Vancouver
City
Vancouver
State/Province
British Columbia
ZIP/Postal Code
V6Z 1Y6
Country
Canada
Facility Name
British Columbia Cancer Agency - Vancouver Island Cancer Centre
City
Victoria
State/Province
British Columbia
ZIP/Postal Code
V8R 6V5
Country
Canada
Facility Name
G. Steinhoff Clinical Research
City
Victoria
State/Province
British Columbia
ZIP/Postal Code
V8V 3N1
Country
Canada
Facility Name
CancerCare Manitoba
City
Winnipeg
State/Province
Manitoba
ZIP/Postal Code
R3E 0V9
Country
Canada
Facility Name
Moncton Hospital
City
Moncton
State/Province
New Brunswick
ZIP/Postal Code
E1C 6ZB
Country
Canada
Facility Name
Doctor Leon Richard Oncology Centre
City
Moncton
State/Province
New Brunswick
ZIP/Postal Code
E1C 8X3
Country
Canada
Facility Name
Saint John Regional Hospital
City
Saint John
State/Province
New Brunswick
ZIP/Postal Code
E2L 4L2
Country
Canada
Facility Name
Newfoundland Cancer Treatment and Research Foundation
City
St. Johns
State/Province
Newfoundland and Labrador
ZIP/Postal Code
A1B 3V6
Country
Canada
Facility Name
Nova Scotia Cancer Centre
City
Halifax
State/Province
Nova Scotia
ZIP/Postal Code
B3H 1V7
Country
Canada
Facility Name
Cape Breton Cancer Centre
City
Sydney
State/Province
Nova Scotia
ZIP/Postal Code
B1P 1P3
Country
Canada
Facility Name
Royal Victoria Hospital, Barrie
City
Barrie
State/Province
Ontario
ZIP/Postal Code
L4M 6M2
Country
Canada
Facility Name
William Osler Health Centre
City
Brampton
State/Province
Ontario
ZIP/Postal Code
L6W 2Z8
Country
Canada
Facility Name
Hamilton and District Urology Association
City
Hamilton
State/Province
Ontario
ZIP/Postal Code
L8N 1T8
Country
Canada
Facility Name
Margaret and Charles Juravinski Cancer Centre
City
Hamilton
State/Province
Ontario
ZIP/Postal Code
L8V 5C2
Country
Canada
Facility Name
Kingston Regional Cancer Centre
City
Kingston
State/Province
Ontario
ZIP/Postal Code
K7L 5P9
Country
Canada
Facility Name
Grand River Regional Cancer Centre
City
Kitchner
State/Province
Ontario
ZIP/Postal Code
N2G 1G3
Country
Canada
Facility Name
London Health Sciences Centre
City
London
State/Province
Ontario
ZIP/Postal Code
N6A 4G5
Country
Canada
Facility Name
Cancer Care Ontario-London Regional Cancer Centre
City
London
State/Province
Ontario
ZIP/Postal Code
N6A 4L6
Country
Canada
Facility Name
Markham Stouffville Hospital
City
Markham
State/Province
Ontario
ZIP/Postal Code
L6B IAI
Country
Canada
Facility Name
Trillium Health Centre
City
Mississauga
State/Province
Ontario
ZIP/Postal Code
L5B 1B8
Country
Canada
Facility Name
Credit Valley Hospital
City
Mississauga
State/Province
Ontario
ZIP/Postal Code
L5M 2N1
Country
Canada
Facility Name
Southlake Regional Health Centre
City
Newmarket
State/Province
Ontario
ZIP/Postal Code
L3Y 2P9
Country
Canada
Facility Name
North York General Hospital, Ontario
City
North York
State/Province
Ontario
ZIP/Postal Code
M2K 1E1
Country
Canada
Facility Name
Sunnybrook and Women's College Health Sciences Centre
City
North York
State/Province
Ontario
ZIP/Postal Code
M4N 3M5
Country
Canada
Facility Name
Male Health Centre - Oakville
City
Oakville
State/Province
Ontario
ZIP/Postal Code
L6H 3PI
Country
Canada
Facility Name
Durham Regional Cancer Centre at Lakeridge Health Oshawa
City
Oshawa
State/Province
Ontario
ZIP/Postal Code
L1G 2B9
Country
Canada
Facility Name
Ottawa Regional Cancer Centre
City
Ottawa
State/Province
Ontario
ZIP/Postal Code
K1H 1C4
Country
Canada
Facility Name
Peterborough Oncology Clinic
City
Peterborough
State/Province
Ontario
ZIP/Postal Code
K9H 7B6
Country
Canada
Facility Name
Algoma Reginal Cancer Program at Sault Area Hospital
City
Sault Sainte Marie
State/Province
Ontario
ZIP/Postal Code
P6B 1Y5
Country
Canada
Facility Name
Scarborough Hospital - General Site
City
Scarborough
State/Province
Ontario
ZIP/Postal Code
M1P 2V5
Country
Canada
Facility Name
Hotel Dieu Health Sciences Hospital - Niagara
City
St. Catharines
State/Province
Ontario
ZIP/Postal Code
L2R 5K3
Country
Canada
Facility Name
Northeastern Ontario Regional Cancer Centre - Sudbury
City
Sudbury
State/Province
Ontario
ZIP/Postal Code
P3E 5J1
Country
Canada
Facility Name
Northwestern Ontario Regional Cancer Care
City
Thunder Bay
State/Province
Ontario
ZIP/Postal Code
P7B 6V4
Country
Canada
Facility Name
Toronto East General Hospital
City
Toronto
State/Province
Ontario
ZIP/Postal Code
M4C 3E7
Country
Canada
Facility Name
Toronto Sunnybrook Regional Cancer Centre
City
Toronto
State/Province
Ontario
ZIP/Postal Code
M4N 3M5
Country
Canada
Facility Name
St. Michael's Hospital - Toronto
City
Toronto
State/Province
Ontario
ZIP/Postal Code
M5B 1W8
Country
Canada
Facility Name
Mount Sinai Hospital - Toronto
City
Toronto
State/Province
Ontario
ZIP/Postal Code
M5G 1X5
Country
Canada
Facility Name
Toronto General Hospital
City
Toronto
State/Province
Ontario
ZIP/Postal Code
M5G 2C4
Country
Canada
Facility Name
Princess Margaret Hospital
City
Toronto
State/Province
Ontario
ZIP/Postal Code
M5G 2M9
Country
Canada
Facility Name
Male Health Centre - North York
City
Toronto
State/Province
Ontario
ZIP/Postal Code
M6A 3B5
Country
Canada
Facility Name
St. Joseph's Health Centre - Toronto
City
Toronto
State/Province
Ontario
ZIP/Postal Code
M6R 1B5
Country
Canada
Facility Name
Humber River Regional Hospital - Weston
City
Weston
State/Province
Ontario
ZIP/Postal Code
M9N 1N8
Country
Canada
Facility Name
Cancer Care Ontario - Windsor Regional Cancer Centre
City
Windsor
State/Province
Ontario
ZIP/Postal Code
N8W 2X3
Country
Canada
Facility Name
Prince Edward Island Cancer Center at Queen Elizabeth Hospital
City
Charlottetown
State/Province
Prince Edward Island
ZIP/Postal Code
C1A 8T5
Country
Canada
Facility Name
Complexe Hospitalier de la Sagamie
City
Chicoutimi
State/Province
Quebec
ZIP/Postal Code
G7H 5H6
Country
Canada
Facility Name
CHUS-Hopital Fleurimont
City
Fleurimont
State/Province
Quebec
ZIP/Postal Code
J1H 5N4
Country
Canada
Facility Name
Hopital Charles Lemoyne
City
Greenfield Park
State/Province
Quebec
ZIP/Postal Code
J4V 2H1
Country
Canada
Facility Name
Centre Hospitalier Regional de Lanaudiere
City
Joliette
State/Province
Quebec
ZIP/Postal Code
J6E 6J2
Country
Canada
Facility Name
Hotel-Dieu de Levis
City
Levis
State/Province
Quebec
ZIP/Postal Code
G6V 3Z1
Country
Canada
Facility Name
Maisonneuve-Rosemont Hospital
City
Montreal
State/Province
Quebec
ZIP/Postal Code
H1T 2M4
Country
Canada
Facility Name
Centre Hospitalier de l'Universite de Montreal
City
Montreal
State/Province
Quebec
ZIP/Postal Code
H2L-4M1
Country
Canada
Facility Name
McGill University
City
Montreal
State/Province
Quebec
ZIP/Postal Code
H2W 1S6
Country
Canada
Facility Name
Hotel Dieu de Montreal
City
Montreal
State/Province
Quebec
ZIP/Postal Code
H2W 1T8
Country
Canada
Facility Name
Hopital Sainte Justine
City
Montreal
State/Province
Quebec
ZIP/Postal Code
H3T 1C5
Country
Canada
Facility Name
Hopital Du Sacre-Coeur de Montreal
City
Montreal
State/Province
Quebec
ZIP/Postal Code
H4J 1C5
Country
Canada
Facility Name
Centre Hospitalier Universitaire de Quebec
City
Quebec City
State/Province
Quebec
ZIP/Postal Code
G1R 2J6
Country
Canada
Facility Name
Hopital du Saint-Sacrement, Quebec
City
Quebec City
State/Province
Quebec
ZIP/Postal Code
G1S 4L8
Country
Canada
Facility Name
L'Hopital Laval
City
Ste-Foy
State/Province
Quebec
ZIP/Postal Code
G1V 4G5
Country
Canada
Facility Name
Allan Blair Cancer Centre
City
Regina
State/Province
Saskatchewan
ZIP/Postal Code
S4T 7T1
Country
Canada
Facility Name
Saskatoon Cancer Centre
City
Saskatoon
State/Province
Saskatchewan
ZIP/Postal Code
S7N 4H4
Country
Canada
Facility Name
Centre Hospitalier Regional de Rimouski
City
Quebec
ZIP/Postal Code
G1S 4L8
Country
Canada
Facility Name
Aarhus Kommunehospital
City
Aarhus
ZIP/Postal Code
DK-8000
Country
Denmark
Facility Name
Rigshospitalet
City
Copenhagen
ZIP/Postal Code
2100
Country
Denmark
Facility Name
Centre Paul Papin
City
Angers
ZIP/Postal Code
49036
Country
France
Facility Name
Institut Bergonie
City
Bordeaux
ZIP/Postal Code
33076
Country
France
Facility Name
Centre Hospitalier Docteur Duchenne
City
Boulogne Sur Mer
ZIP/Postal Code
62200
Country
France
Facility Name
Centre Regional Francois Baclesse
City
Caen
ZIP/Postal Code
14076
Country
France
Facility Name
Centre Hospitalier Universitaire Henri Mondor
City
Creteil
ZIP/Postal Code
94010
Country
France
Facility Name
Centre de Lutte Contre le Cancer, Georges-Francois Leclerc
City
Dijon
ZIP/Postal Code
21079
Country
France
Facility Name
CHU de Grenoble - Hopital de la Tronche
City
Grenoble
ZIP/Postal Code
38043
Country
France
Facility Name
Centre Hospitalier Departemental
City
La Roche Sur Yon
ZIP/Postal Code
F-85025
Country
France
Facility Name
Centre Oscar Lambret
City
Lille
ZIP/Postal Code
59020
Country
France
Facility Name
Centre Leon Berard
City
Lyon
ZIP/Postal Code
69373
Country
France
Facility Name
CHU de la Timone
City
Marseille
ZIP/Postal Code
13385
Country
France
Facility Name
Hopital Lapeyronie-CHU Montpellier
City
Montpellier
ZIP/Postal Code
34295
Country
France
Facility Name
Centre Regional de Lutte Contre le Cancer - Centre Val d'Aurelle
City
Montpellier
ZIP/Postal Code
34298
Country
France
Facility Name
Centre Regional Rene Gauducheau
City
Nantes-Saint Herblain
ZIP/Postal Code
44805
Country
France
Facility Name
Hopital Europeen Georges Pompidou
City
Paris
ZIP/Postal Code
75015
Country
France
Facility Name
Institut Curie - Section Medicale
City
Paris
ZIP/Postal Code
75248
Country
France
Facility Name
Hopital Tenon
City
Paris
ZIP/Postal Code
75970
Country
France
Facility Name
Centre Eugene Marquis
City
Rennes
ZIP/Postal Code
35042
Country
France
Facility Name
Centre Henri Becquerel
City
Rouen
ZIP/Postal Code
76038
Country
France
Facility Name
Centre Rene Huguenin
City
Saint Cloud
ZIP/Postal Code
92211
Country
France
Facility Name
Centre Medico-Chirurgical Foch
City
Suresnes
ZIP/Postal Code
92151
Country
France
Facility Name
Centre Antoine Lacassagne
City
Toulouse
ZIP/Postal Code
31052
Country
France
Facility Name
Institut Claudius Regaud
City
Toulouse
ZIP/Postal Code
31052
Country
France
Facility Name
Centre Alexis Vautrin
City
Vandoeuvre-les-Nancy
ZIP/Postal Code
54511
Country
France
Facility Name
Krankenhaus Hohe Warte Mediziniche Klinik
City
Bayreuth
ZIP/Postal Code
95445
Country
Germany
Facility Name
Charite Humboldt - University Berlin
City
Berlin
ZIP/Postal Code
D-10117
Country
Germany
Facility Name
Charite - Universitaetsmedizin Berlin - Campus Benjamin Franklin
City
Berlin
ZIP/Postal Code
D-12200
Country
Germany
Facility Name
Helios - Klinik Blankenhain
City
Blankenhain
ZIP/Postal Code
99444
Country
Germany
Facility Name
Universitaetsklinikum Bonn
City
Bonn
ZIP/Postal Code
D-53105
Country
Germany
Facility Name
Staedtische Kliniken Dortmund
City
Dortmund
ZIP/Postal Code
44143
Country
Germany
Facility Name
Universitaetsklinik Duesseldorf
City
Duesseldorf
ZIP/Postal Code
D-40225
Country
Germany
Facility Name
St. Markus Krankenhaus
City
Frankfurt
ZIP/Postal Code
60431
Country
Germany
Facility Name
Klinikum der J.W. Goethe Universitaet
City
Frankfurt
ZIP/Postal Code
D-60590
Country
Germany
Facility Name
Klinikum Fulda
City
Fulda
ZIP/Postal Code
D-36013
Country
Germany
Facility Name
Martin Luther Universitaet
City
Halle
ZIP/Postal Code
D-06097
Country
Germany
Facility Name
Marienkrankenhaus
City
Hamburg
ZIP/Postal Code
22087
Country
Germany
Facility Name
Universitat des Saarlandes Innere Medizin 1
City
Hamburg
ZIP/Postal Code
D-66421
Country
Germany
Facility Name
Klinikum der Friedrich-Schiller Universitaet Jena
City
Jena
ZIP/Postal Code
D-07740
Country
Germany
Facility Name
Klinikum der Stadt Ludwigshafen am Rhein
City
Ludwigshafen am Rhein
ZIP/Postal Code
D-67063
Country
Germany
Facility Name
Staedtisches Krankenhaus Sued
City
Luebeck
ZIP/Postal Code
23560
Country
Germany
Facility Name
Medizinische Universitaet Luebeck
City
Luebeck
ZIP/Postal Code
D-23538
Country
Germany
Facility Name
Kreiskrankenhaus Luedenscheid
City
Luedenscheid
ZIP/Postal Code
58515
Country
Germany
Facility Name
Klinikum der Stadt Mannheim
City
Mannheim
ZIP/Postal Code
D-68135
Country
Germany
Facility Name
University of Marburg
City
Marburg
ZIP/Postal Code
D-35033
Country
Germany
Facility Name
Klinik und Poliklinik fuer Kinderheilkunde
City
Muenster
ZIP/Postal Code
D-48129
Country
Germany
Facility Name
Klinikum Rechts Der Isar - Technische Universitaet Muenchen
City
Munich
ZIP/Postal Code
D-81675
Country
Germany
Facility Name
Klinikum Neubrandenburg
City
Neubrandenburg
ZIP/Postal Code
17036
Country
Germany
Facility Name
Klinikum Nuernberg - Klinikum Nord
City
Nuernberg
ZIP/Postal Code
D-90419
Country
Germany
Facility Name
Paracelsus Karankenhaus Ruit
City
Ostfildern
ZIP/Postal Code
73760
Country
Germany
Facility Name
Asklepios Klinik Pasewalk
City
Pasewalk
ZIP/Postal Code
17309
Country
Germany
Facility Name
Diakonie - Krankenhaus
City
Rotenburg
ZIP/Postal Code
DOH-27356
Country
Germany
Facility Name
Johanniter Kankenhaus Stendal
City
Stendal
ZIP/Postal Code
39576
Country
Germany
Facility Name
Katharinenhospital
City
Stuttgart
ZIP/Postal Code
D-70174
Country
Germany
Facility Name
Universitaetsklinikum Tuebingen
City
Tuebingen
ZIP/Postal Code
D-72076
Country
Germany
Facility Name
Universitaet Ulm
City
Ulm
ZIP/Postal Code
D-89075
Country
Germany
Facility Name
Klinikum der Stadt Wolfsburg
City
Wolfsburg
ZIP/Postal Code
D-38440
Country
Germany
Facility Name
Klinikum St. Marien
City
Wuppertal
ZIP/Postal Code
D-42283
Country
Germany
Facility Name
Witten University - Klinikum Wuppertal
City
Wuppertal
ZIP/Postal Code
D-42283
Country
Germany
Facility Name
National Institute of Oncology
City
Budapest
ZIP/Postal Code
1125
Country
Hungary
Facility Name
Rabin Medical Center - Beilinson Campus
City
Petah-Tikva
ZIP/Postal Code
49100
Country
Israel
Facility Name
Assaf Harofeh Medical Center
City
Zerifin
ZIP/Postal Code
70300
Country
Israel
Facility Name
Ospedale Santa Croce
City
Cuneo
ZIP/Postal Code
12100
Country
Italy
Facility Name
Istituto Scientifico H.San Raffaele
City
Milano
ZIP/Postal Code
20132
Country
Italy
Facility Name
Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital
City
Amsterdam
ZIP/Postal Code
1066 CX
Country
Netherlands
Facility Name
Jeroen Bosch Ziekenhuis
City
NL'S Hertogenbosch
ZIP/Postal Code
NL-5211
Country
Netherlands
Facility Name
Daniel Den Hoed Cancer Center at Erasmus Medical Center
City
Rotterdam
ZIP/Postal Code
3008 AE
Country
Netherlands
Facility Name
Academisch Ziekenhuis Utrecht
City
Utrecht
ZIP/Postal Code
3584 CX
Country
Netherlands
Facility Name
University Hospital - Rotterdam Dijkzigt
City
Utrecht
ZIP/Postal Code
3584 CX
Country
Netherlands
Facility Name
Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology
City
Warsaw
ZIP/Postal Code
02-781
Country
Poland
Facility Name
National Cancer Institute - Bratislava
City
Bratislava
ZIP/Postal Code
833 10
Country
Slovakia
Facility Name
Hospital Universitari Germans Trias i Pujol
City
Badalona
ZIP/Postal Code
08916
Country
Spain
Facility Name
Hospital Del Mar
City
Barcelona
ZIP/Postal Code
08003
Country
Spain
Facility Name
Hospital Clinic y Provincial de Barcelona
City
Barcelona
ZIP/Postal Code
08036
Country
Spain
Facility Name
Hospital General Universitari Vall d'Hebron
City
Barcelona
ZIP/Postal Code
08036
Country
Spain
Facility Name
Hospital Juan Canalejo
City
Coruna
ZIP/Postal Code
15006
Country
Spain
Facility Name
Hospital General Universitario De Guadalajara
City
Guadalajara
ZIP/Postal Code
19002
Country
Spain
Facility Name
Hospital Cuidad de Jaen
City
Jaen
ZIP/Postal Code
E-23006
Country
Spain
Facility Name
Hospital Arquitecto Marcide
City
La Coruna
ZIP/Postal Code
15405
Country
Spain
Facility Name
Hospital Universitario San Carlos
City
Madrid
ZIP/Postal Code
28040
Country
Spain
Facility Name
Hospital Universitario 12 de Octubre
City
Madrid
ZIP/Postal Code
28041
Country
Spain
Facility Name
Hospital Clinico Universitario - Malaga
City
Malaga
ZIP/Postal Code
29010
Country
Spain
Facility Name
Hospital Son Dureta
City
Palma De Mallorca
ZIP/Postal Code
07014
Country
Spain
Facility Name
Hospsital de Sabadell
City
Sabadell
ZIP/Postal Code
08208
Country
Spain
Facility Name
Hospital Universitario Marques de Valdecilla
City
Santander
ZIP/Postal Code
39008
Country
Spain
Facility Name
Hospital Consorci Sanitari De Terrassa
City
Terrassa
ZIP/Postal Code
08227
Country
Spain
Facility Name
Instituto Valenciano De Oncologia
City
Valencia
ZIP/Postal Code
46009
Country
Spain
Facility Name
Hospital Clinico Universitario de Valencia
City
Valencia
ZIP/Postal Code
46010
Country
Spain
Facility Name
Hospital Rio Hortega
City
Valladolid
ZIP/Postal Code
47010
Country
Spain
Facility Name
Hospital General De Vic
City
Vic
ZIP/Postal Code
08500
Country
Spain
Facility Name
Hospital Clinico Universitario
City
Zaragoza
ZIP/Postal Code
50009
Country
Spain
Facility Name
Princess Royal Hospital
City
Hull
State/Province
England
ZIP/Postal Code
HU8 9HE
Country
United Kingdom
Facility Name
St. James's University Hospital
City
Leeds
State/Province
England
ZIP/Postal Code
LS9 7TF
Country
United Kingdom
Facility Name
Saint Bartholomew's Hospital
City
London
State/Province
England
ZIP/Postal Code
EC1A 7BE
Country
United Kingdom
Facility Name
Guy's and St. Thomas' Hospitals NHS Trust
City
London
State/Province
England
ZIP/Postal Code
SE1 9RT
Country
United Kingdom
Facility Name
Northern Centre for Cancer Treatment at Newcastle General Hospital
City
Newcastle Upon Tyne
State/Province
England
ZIP/Postal Code
NE4 6BE
Country
United Kingdom
Facility Name
Royal South Hants Hospital
City
Southampton
State/Province
England
ZIP/Postal Code
SO14 0YG
Country
United Kingdom
Facility Name
Royal Marsden Hospital - Sutton
City
Sutton
State/Province
England
ZIP/Postal Code
SM2 5PT
Country
United Kingdom
Facility Name
Velindre Cancer Center at Velinde Hospital
City
Cardiff
State/Province
Wales
ZIP/Postal Code
CF14 2TL
Country
United Kingdom

12. IPD Sharing Statement

Citations:
PubMed Identifier
22370319
Citation
Bellmunt J, von der Maase H, Mead GM, Skoneczna I, De Santis M, Daugaard G, Boehle A, Chevreau C, Paz-Ares L, Laufman LR, Winquist E, Raghavan D, Marreaud S, Collette S, Sylvester R, de Wit R. Randomized phase III study comparing paclitaxel/cisplatin/gemcitabine and gemcitabine/cisplatin in patients with locally advanced or metastatic urothelial cancer without prior systemic therapy: EORTC Intergroup Study 30987. J Clin Oncol. 2012 Apr 1;30(10):1107-13. doi: 10.1200/JCO.2011.38.6979. Epub 2012 Feb 27. Erratum In: J Clin Oncol. 2018 Mar 10;36(8):833.
Results Reference
result

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Cisplatin Plus Gemcitabine With or Without Paclitaxel in Treating Patients With Stage IV Urinary Tract Cancer

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