Management of Compartment Syndrome With Ultrafiltration
Compartment Syndrome
About this trial
This is an interventional treatment trial for Compartment Syndrome focused on measuring Compartment syndrome, Tissue ultrafiltration, Reperfusion injury, Ischemia
Eligibility Criteria
Inclusion Criteria: The patient has a closed or open Gustilo grade I, grade II, or grade IIIa tibial shaft fracture that is going to be treated with surgical stabilization under general anesthesia. An open fracture must have sufficient skin for wound coverage. The patient has a single tibial fracture. The patient is mentally alert and able to sign his or her own consent form. Patient is at least 60" in height. Patient is between 14 and 80 years of age. Exclusion Criteria: The patient previously had a fracture in the same leg. The patient has a Gustilo grade IIIb open fracture. The patient has a Tscherne grade II or Tscherne grade III injury. Patients with evidence of compartment syndrome at the time of admission. The patient is obese, with body mass index greater than 35 (km/m2). Have medical condition(s) that precludes use of indwelling catheters for 24 hours, such as dermatologic conditions or immunological deficits. Have co-morbidities that may place the patient at risk of hypotension (e.g., significant blood loss, heart failure, significant chest or abdominal trauma, septicemia, or massive soft tissue trauma).
Sites / Locations
- Hennepin County Medical Center