Curcumin for the Prevention of Colon Cancer
Colorectal Cancer
About this trial
This is an interventional prevention trial for Colorectal Cancer focused on measuring colon cancer
Eligibility Criteria
DISEASE CHARACTERISTICS: Healthy men and women age 18 and over PATIENT CHARACTERISTICS: Age: 18 and over Performance status: Not specified Life expectancy: Not specified Hematopoietic: WBC greater than 4,000/mm3 Hemoglobin greater than 12 g/dL Platelet count greater than 120,000/mm3 Hepatic: ALT/AST less than 1.5 times upper limit of normal (ULN) Alkaline phosphatase less than 1.5 times ULN Bilirubin less than 1.5 mg/dL Renal: Creatinine less than 1.7 mg/dL Other: Not pregnant or nursing Negative pregnancy test Fertile patients must use effective contraception No prior cancer except surgically resected basal cell or squamous cell skin cancer No history of peptic ulcer disease, gastrointestinal bleeding from gastric or duodenal ulcers, or gastrin secreting tumors No history of unreliability or noncompliance (missing pretreatment appointment more than twice) PRIOR CONCURRENT THERAPY: Biologic therapy: Not specified Chemotherapy: Not specified Endocrine therapy: At least 14 days since prior steroids Radiotherapy: Not specified Surgery: Not specified Other: At least 14 days since prior curcumin (turmeric) rich foods At least 14 days since prior nonsteroidal antiinflammatory drugs (NSAIDs) No chronic medications (i.e., daily for more than 28 days) except for oral contraceptives No concurrent coumadin or other anticoagulants
Sites / Locations
- University of Michigan Comprehensive Cancer Center