Long Term Post Operative Follow-Up of Cushing Syndrome
Cushing Syndrome
About this trial
This is an observational trial for Cushing Syndrome focused on measuring Cortisol, Bone Density, Cushing Syndrome, Postoperative
Eligibility Criteria
INCLUSION CRITERIA: Patients with Cushing syndrome documented at the NIH will be recruited into this protocol prior to surgery intended to cure Cushing syndrome selectively. Thus, patients undergoing transsphenoidal exploration for resection of an adenoma, or unilateral adrenalectomy for an adenoma, or resection of a tumor producing ACTH ectopically will be candidates for this study. We will also recruit as many of the 500 patients treated since 1983 as possible, so as to have a group of "late follow-up" patients. These individuals will participate primarily by questionnaire. Hematocrit about 30%. A CBC will be obtained prior to entering the study. Patients with hematocrit above 30% will be accepted into the study; iron replacement will be given to those patients with low TIBC. Ages 18 - 85. Children less than 18 are being studied under other protocols and the questionnaire has not been validated for younger individuals. For the questionnaire portion of the protocol there is an additional inclusion criterion: Patients must be able to read and write in English. EXCLUSION CRITERIA: There are no formal exclusion criteria, if the patient meets the inclusion criteria above. All ethnic groups and both genders will be recruited. However, patients may be withdrawn from the study by the PI if they are unable to meet study requirments, such as mailing questionnaires.
Sites / Locations
- National Institute of Child Health and Human Development (NICHD)