Brain Imaging and Retreatment Study of Persistent Lyme Disease
Lyme Disease, Lyme Neuroborreliosis
About this trial
This is an interventional treatment trial for Lyme Disease focused on measuring neurologic Lyme disease, Lyme disease, ceftriaxone, Rocephin, PET scans, Lyme encephalopathy, neuroborreliosis, borreliosis
Eligibility Criteria
Inclusion Criteria: Eligible participants must: Be 18-65 years old Have persistent problems with memory, verbal fluency, or attention after having contracted Lyme disease. Be able to travel to New York for 4-5 evaluations over the course of one year. Travel costs for participants in need may be partially or fully reimbursable. Have had a history of well-documented Lyme disease using the CDC's clinical criteria and a current positive IgG Western blot or PCR. Have received, at some point in the past at least 3 weeks of IV antibiotic therapy for Lyme disease. Exclusion Criteria: Ineligible from participation are people with the following: Other major medical or neurologic problems Smoke more than 10 cigarettes a day Uncontrolled high blood pressure Allergy to ceftriaxone (Rocephin) History of marked cocaine abuse Twenty healthy subjects are also being sought for the study.
Sites / Locations
- Columbia Presbyterian Medical Center