Back to resultsA Study to Evaluate the Effects of ONO-2506 Intravenous Infusion in Patients With Acute Ischemic Stroke
Primary Purpose
Cerebrovascular Accident
Status
Terminated
Phase
Phase 2
Locations
International
Study Type
Interventional
Intervention
ONO-2506
Sponsored by
About this trial
This is an interventional treatment trial for Cerebrovascular Accident focused on measuring Acute Ischemic Stroke
Eligibility Criteria
Inclusion Criteria: Patient must have a clinical diagnosis of acute cortical ischemic stroke. Patient must be randomized into the study within six hours after the initial onset of stroke symptoms. Patient must have a measurable focal neurological deficit for a minimum duration of 60 minutes. Patient must have a CT or MRI examination compatible with the clinical diagnosis of acute ischemic stroke. Patient must have had a pre-stroke mRS scale score of 0 or 1. Other inclusion criteria as specified in the study protocol. Exclusion Criteria: Patient must not have a body weight of more than 125 kg. Patient must not have a CT and/or MRI with evidence of a non-ischemic mechanism, subarachnoid hemorrhage, or primary intracerebral and/or intraventricular hemorrhage. Patient must not have all three of the following findings: reduced level of consciousness (has score of greater than or equal to two on NIHSS Question 1a) forced eye deviation or total gaze paresis (has score of 2 on NIHSS Question 2) and dense hemiplegia (no movement) of upper and lower extremities (i.e., has score of 4 on NIHSS Question 5 regarding motor arm and has score of 4 on NIHSS Question 6 regarding motor leg). Patient must not have neurological signs and symptoms that are rapidly improving. Patient must not have a severe coexisting or terminal systemic disease. Patient must not be pregnant or lactating. Patient must not have impaired hepatic function; bilirubin greater than 2 mg/dL and or ascites. Patient must not have impaired renal function; serum creatinine greater than 2 mg/dL. Patient must not have congestive heart failure. Patient must not have a baseline ECG showing a PR interval greater than 200 milliseconds, or a corrected QT interval of greater than 480 milliseconds, or a history of ventricular arrhythmias, or a Mobitz Type 1 or greater AV block. Patient must not have other exclusion criteria as specified in the study protocol.
Sites / Locations
- Brookwood Medical Center
- University of Alabama
- Alta Bates Hospital/ Summit Medical Center
- Grossmont Hospital
- Loma Linda University Medical Center
- UCLA Medical Center
- Stanford Stroke Center
- Mercy Medical Center
- Redding Medical Center
- UC Davis Medical Center
- Good Samaritan Hospital
- Bridgeport Hospital
- The Stroke Center at Hartford Hospital
- Yale - New Haven Hospital
- Morton Plant Hospital
- North Broward Medical Center
- Alachua General Hospital
- Aventura Hospital and Medical Center
- Neurology Associates, PA
- Baptist Hospital of Miami
- Ocala Regional Medical Center
- Munroe Regional Medical Center
- BonSecours - St. Joseph's Hospital
- Charlotte Regional Medical Center
- Fawcett Memorial Hospital
- Bayfront Medical Center
- Palms of Pasadina Hospital
- St. Joseph Hospital
- Tampa General Hospital
- Memorial Hospital of Tampa
- Cleveland Clinic Florida
- St. Francis Hospital
- DeKalb Medical Center
- Gwinnett Medical Center
- Joan Glancy Memorial Hospital
- Queen's Medical Center
- MacNeal Hospital
- BroMenn Regional Medical Center
- OSF St. Joseph Medical Center
- Alexian Brothers Hospital
- Advocate Christ Hospital & Medical Center
- St. John's Hospital
- Memorial Medical Center
- Central DuPage Hospital
- Elkhart General Hospital
- Lutheran Hospital of Indiana
- Parkview Hospital
- Mercy Hospital Medical Center
- University of Kansas Medical Center
- Lexington Clinic
- Chandler Medical Center /Univ of Kentucky
- University of Louisville Hospital
- Ochsner Clinic Foundation
- LSU Health Sciences Center
- Sinai Hospital of Baltimore
- University of Massachusetts Medical Center
- Detroit Receiving Hospital/ Wayne State Univ
- Borgess Research Institute
- William Beaumont Hospital
- St. Cloud Hospital
- North Mississippi Medical Center
- St. John's Clinic - Smith-Glynn-Callaway
- Benefits Healthcare/ Advanced Neurology Specialists
- Creighton University Medical Center
- Washoe Medical Center
- Cooper Hospital /University Medical Center
- JFK Medical Center
- Englewood Hospital and Medical Center
- Virtua Memorial Hospital
- Robert Wood Johnson Hospital
- Muhlenberg Hospital
- Valley Hospital
- Overlook Hospital
- Community Medical Center
- St. Francis Medical Center
- St. Peter's Hospital
- Buffalo General Hospital
- Millard Fillmore Hospital
- Wilson Memorial Regional Medical Center
- North Shore University Hospital
- Winthrop University Hospital
- Mount Vernon Hospital
- Long Island Jewish Medical Center
- Mt. Sinai Hospital
- Rochester General Hospital
- Strong Memorial Hospital
- Ellis Hospital Stroke Center B421
- SUNY Stony Brook University Hospital
- University of North Carolina Hospital
- Rowan Regional Medical Center
- Forsyth Medical Center
- Akron General Medical Center
- University Hospitals of Cleveland
- Metrohealth Medical Center
- Kettering Medical Center -Wallace Kettering Neuroscience Inst.
- Medical College of Ohio Hospital
- St. Elizabeth's Health Center
- Rogue Valley Medical Center
- Oregon Health and Science University - Oregon Stroke Center
- Providence Portland Medical Center
- Providence St. Vincent's Hospital
- Lehigh Valley Hospital
- Westmoreland Regional Hospital
- University of Pennsylvania Medical Center
- Thomas Jefferson University Hospital
- University of Pittsburg Medical Center
- Crozer Chester Medical Center
- York Hospital
- Miriam Hospital
- Greenville Hospital
- Erlanger Hospital
- Regional Medical Center at Memphis
- Vanderbilt University Medical Center
- Baylor University Medical Center
- University of Texas; Southwestern Medical Center at Dallas
- Methodist Hospital /Baylor College of Medicine
- The Methodist Hospital
- University Hospital /Univ of Texas Health Science Center
- University of Utah Medical Center
- The Innovative Clincal Research Center
- Virginia Commonwealth University /Medical College of VA
- Henrico Doctors Hospital
- Memorial Regional Medical Center
- St. Mary's Hospital
- Harborview Medical Center
- Charleston Area Medical Center
- University of Wisconsin Hospitals and Clinics
- St. Joseph's Hospital/ Marshfield Clinic
- St. Luke's Medical Center
- Theda Clark Medical Center
- Foothills Medical Center /University of Calgary
- University of Alberta Hospital /Mackenzie Center
- Lethbridge Regional Hospital
- Royal Inland Hospital
- Kelowna General Hospital
- St Paul's Hospital
- Vancouver General Hospital
- Royal Jubilee Hospital
- Kingston General Hospital
- London Health Sciences Centre
- Trillium Health Centre
- York Central Hospital
- Complexe Hospitalier de La Sagamie
- Centre Hospitalier des Vallees de l'Outaouais
- Hotel-Dieu de Levis
- Hospital Notre Dame du Chum
- Hotel-Dieu de St-Jerome
- Royal University Hospital
Outcomes
Primary Outcome Measures
Modified Rankin Scale
Secondary Outcome Measures
Full Information
1. Study Identification
Unique Protocol Identification Number
NCT00046761
Brief Title
A Study to Evaluate the Effects of ONO-2506 Intravenous Infusion in Patients With Acute Ischemic Stroke
Official Title
A Study to Evaluate the Effects of ONO-2506 Intravenous Infusion in Patients With Acute Ischemic Stroke
Study Type
Interventional
2. Study Status
Record Verification Date
October 2012
Overall Recruitment Status
Terminated
Study Start Date
November 2002 (undefined)
Primary Completion Date
May 2005 (Actual)
Study Completion Date
undefined (undefined)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Ono Pharma USA Inc
4. Oversight
5. Study Description
Brief Summary
The primary objective of this study is to compare the efficacy of ONO-2506 versus placebo in neurological stroke outcome in patients with acute ischemic stroke.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Cerebrovascular Accident
Keywords
Acute Ischemic Stroke
7. Study Design
Primary Purpose
Treatment
Study Phase
Phase 2, Phase 3
Interventional Study Model
Parallel Assignment
Masking
Double
Allocation
Randomized
Enrollment
1320 (false)
8. Arms, Groups, and Interventions
Intervention Type
Drug
Intervention Name(s)
ONO-2506
Primary Outcome Measure Information:
Title
Modified Rankin Scale
10. Eligibility
Sex
All
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
Patient must have a clinical diagnosis of acute cortical ischemic stroke.
Patient must be randomized into the study within six hours after the initial onset of stroke symptoms.
Patient must have a measurable focal neurological deficit for a minimum duration of 60 minutes.
Patient must have a CT or MRI examination compatible with the clinical diagnosis of acute ischemic stroke.
Patient must have had a pre-stroke mRS scale score of 0 or 1.
Other inclusion criteria as specified in the study protocol.
Exclusion Criteria:
Patient must not have a body weight of more than 125 kg.
Patient must not have a CT and/or MRI with evidence of a non-ischemic mechanism, subarachnoid hemorrhage, or primary intracerebral and/or intraventricular hemorrhage.
Patient must not have all three of the following findings:
reduced level of consciousness (has score of greater than or equal to two on NIHSS Question 1a)
forced eye deviation or total gaze paresis (has score of 2 on NIHSS Question 2) and
dense hemiplegia (no movement) of upper and lower extremities (i.e., has score of 4 on NIHSS Question 5 regarding motor arm and has score of 4 on NIHSS Question 6 regarding motor leg).
Patient must not have neurological signs and symptoms that are rapidly improving.
Patient must not have a severe coexisting or terminal systemic disease.
Patient must not be pregnant or lactating.
Patient must not have impaired hepatic function; bilirubin greater than 2 mg/dL and or ascites.
Patient must not have impaired renal function; serum creatinine greater than 2 mg/dL.
Patient must not have congestive heart failure.
Patient must not have a baseline ECG showing a PR interval greater than 200 milliseconds, or a corrected QT interval of greater than 480 milliseconds, or a history of ventricular arrhythmias, or a Mobitz Type 1 or greater AV block.
Patient must not have other exclusion criteria as specified in the study protocol.
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Bryan Due, Ph.D.
Organizational Affiliation
Ono Pharma USA Inc
Official's Role
Study Director
Facility Information:
Facility Name
Brookwood Medical Center
City
Birmingham
State/Province
Alabama
ZIP/Postal Code
35209
Country
United States
Facility Name
University of Alabama
City
Birmingham
State/Province
Alabama
ZIP/Postal Code
35294
Country
United States
Facility Name
Alta Bates Hospital/ Summit Medical Center
City
Berkeley
State/Province
California
ZIP/Postal Code
94705
Country
United States
Facility Name
Grossmont Hospital
City
La Mesa
State/Province
California
ZIP/Postal Code
91942
Country
United States
Facility Name
Loma Linda University Medical Center
City
Loma Linda
State/Province
California
ZIP/Postal Code
92354
Country
United States
Facility Name
UCLA Medical Center
City
Los Angeles
State/Province
California
ZIP/Postal Code
90024
Country
United States
Facility Name
Stanford Stroke Center
City
Palo Alto
State/Province
California
ZIP/Postal Code
94304
Country
United States
Facility Name
Mercy Medical Center
City
Redding
State/Province
California
ZIP/Postal Code
96001
Country
United States
Facility Name
Redding Medical Center
City
Redding
State/Province
California
ZIP/Postal Code
96001
Country
United States
Facility Name
UC Davis Medical Center
City
Sacramento
State/Province
California
ZIP/Postal Code
95817
Country
United States
Facility Name
Good Samaritan Hospital
City
San Jose
State/Province
California
ZIP/Postal Code
95124
Country
United States
Facility Name
Bridgeport Hospital
City
Bridgeport
State/Province
Connecticut
ZIP/Postal Code
06610
Country
United States
Facility Name
The Stroke Center at Hartford Hospital
City
Hartford
State/Province
Connecticut
ZIP/Postal Code
06106
Country
United States
Facility Name
Yale - New Haven Hospital
City
New Haven
State/Province
Connecticut
ZIP/Postal Code
06520
Country
United States
Facility Name
Morton Plant Hospital
City
Clearwater
State/Province
Florida
ZIP/Postal Code
33756
Country
United States
Facility Name
North Broward Medical Center
City
Ft. Lauderdale
State/Province
Florida
ZIP/Postal Code
33308
Country
United States
Facility Name
Alachua General Hospital
City
Gainsville
State/Province
Florida
ZIP/Postal Code
32605
Country
United States
Facility Name
Aventura Hospital and Medical Center
City
Hollywood
State/Province
Florida
ZIP/Postal Code
33021
Country
United States
Facility Name
Neurology Associates, PA
City
Maitland
State/Province
Florida
ZIP/Postal Code
32751
Country
United States
Facility Name
Baptist Hospital of Miami
City
Miami
State/Province
Florida
ZIP/Postal Code
33156
Country
United States
Facility Name
Ocala Regional Medical Center
City
Ocala
State/Province
Florida
ZIP/Postal Code
34471
Country
United States
Facility Name
Munroe Regional Medical Center
City
Ocala
State/Province
Florida
ZIP/Postal Code
34478
Country
United States
Facility Name
BonSecours - St. Joseph's Hospital
City
Port Charlotte
State/Province
Florida
ZIP/Postal Code
33952
Country
United States
Facility Name
Charlotte Regional Medical Center
City
Port Charlotte
State/Province
Florida
ZIP/Postal Code
33952
Country
United States
Facility Name
Fawcett Memorial Hospital
City
Port Charlotte
State/Province
Florida
ZIP/Postal Code
33952
Country
United States
Facility Name
Bayfront Medical Center
City
St. Petersburg
State/Province
Florida
ZIP/Postal Code
33701
Country
United States
Facility Name
Palms of Pasadina Hospital
City
St. Petersburg
State/Province
Florida
ZIP/Postal Code
33707
Country
United States
Facility Name
St. Joseph Hospital
City
Tampa
State/Province
Florida
ZIP/Postal Code
33606
Country
United States
Facility Name
Tampa General Hospital
City
Tampa
State/Province
Florida
ZIP/Postal Code
33606
Country
United States
Facility Name
Memorial Hospital of Tampa
City
Tampa
State/Province
Florida
ZIP/Postal Code
33608
Country
United States
Facility Name
Cleveland Clinic Florida
City
Weston
State/Province
Florida
ZIP/Postal Code
33331
Country
United States
Facility Name
St. Francis Hospital
City
Columbus
State/Province
Georgia
ZIP/Postal Code
31901
Country
United States
Facility Name
DeKalb Medical Center
City
Decatur
State/Province
Georgia
ZIP/Postal Code
30033
Country
United States
Facility Name
Gwinnett Medical Center
City
Decatur
State/Province
Georgia
ZIP/Postal Code
30033
Country
United States
Facility Name
Joan Glancy Memorial Hospital
City
Decatur
State/Province
Georgia
ZIP/Postal Code
30034
Country
United States
Facility Name
Queen's Medical Center
City
Honolulu
State/Province
Hawaii
ZIP/Postal Code
96813
Country
United States
Facility Name
MacNeal Hospital
City
Berwyn
State/Province
Illinois
ZIP/Postal Code
60402
Country
United States
Facility Name
BroMenn Regional Medical Center
City
Bloomington
State/Province
Illinois
ZIP/Postal Code
61704
Country
United States
Facility Name
OSF St. Joseph Medical Center
City
Bloomington
State/Province
Illinois
ZIP/Postal Code
61704
Country
United States
Facility Name
Alexian Brothers Hospital
City
Elk Grove Village
State/Province
Illinois
ZIP/Postal Code
60007
Country
United States
Facility Name
Advocate Christ Hospital & Medical Center
City
Oak Lawn
State/Province
Illinois
ZIP/Postal Code
60453
Country
United States
Facility Name
St. John's Hospital
City
Springfield
State/Province
Illinois
ZIP/Postal Code
62702
Country
United States
Facility Name
Memorial Medical Center
City
Springfield
State/Province
Illinois
ZIP/Postal Code
62781
Country
United States
Facility Name
Central DuPage Hospital
City
Warrenville
State/Province
Illinois
ZIP/Postal Code
60555
Country
United States
Facility Name
Elkhart General Hospital
City
Elkhart
State/Province
Indiana
ZIP/Postal Code
46540
Country
United States
Facility Name
Lutheran Hospital of Indiana
City
Fort Wayne
State/Province
Indiana
ZIP/Postal Code
46804
Country
United States
Facility Name
Parkview Hospital
City
Fort Wayne
State/Province
Indiana
ZIP/Postal Code
46805
Country
United States
Facility Name
Mercy Hospital Medical Center
City
Des Moines
State/Province
Iowa
ZIP/Postal Code
50314
Country
United States
Facility Name
University of Kansas Medical Center
City
Kansas City
State/Province
Kansas
ZIP/Postal Code
66160
Country
United States
Facility Name
Lexington Clinic
City
Lexington
State/Province
Kentucky
ZIP/Postal Code
40504
Country
United States
Facility Name
Chandler Medical Center /Univ of Kentucky
City
Lexington
State/Province
Kentucky
ZIP/Postal Code
40536
Country
United States
Facility Name
University of Louisville Hospital
City
Louisville
State/Province
Kentucky
ZIP/Postal Code
40202
Country
United States
Facility Name
Ochsner Clinic Foundation
City
New Orleans
State/Province
Louisiana
ZIP/Postal Code
70121
Country
United States
Facility Name
LSU Health Sciences Center
City
Shreveport
State/Province
Louisiana
ZIP/Postal Code
71130
Country
United States
Facility Name
Sinai Hospital of Baltimore
City
Baltimore
State/Province
Maryland
ZIP/Postal Code
21215
Country
United States
Facility Name
University of Massachusetts Medical Center
City
Worcester
State/Province
Massachusetts
ZIP/Postal Code
01655
Country
United States
Facility Name
Detroit Receiving Hospital/ Wayne State Univ
City
Detroit
State/Province
Michigan
ZIP/Postal Code
48201
Country
United States
Facility Name
Borgess Research Institute
City
Kalamazoo
State/Province
Michigan
ZIP/Postal Code
49048
Country
United States
Facility Name
William Beaumont Hospital
City
Royal Oak
State/Province
Michigan
ZIP/Postal Code
48073
Country
United States
Facility Name
St. Cloud Hospital
City
St. Cloud
State/Province
Minnesota
ZIP/Postal Code
56303
Country
United States
Facility Name
North Mississippi Medical Center
City
Tupelo
State/Province
Mississippi
ZIP/Postal Code
38801
Country
United States
Facility Name
St. John's Clinic - Smith-Glynn-Callaway
City
Springfield
State/Province
Missouri
ZIP/Postal Code
65804
Country
United States
Facility Name
Benefits Healthcare/ Advanced Neurology Specialists
City
Great Falls
State/Province
Montana
ZIP/Postal Code
59405
Country
United States
Facility Name
Creighton University Medical Center
City
Omaha
State/Province
Nebraska
ZIP/Postal Code
68131
Country
United States
Facility Name
Washoe Medical Center
City
Reno
State/Province
Nevada
ZIP/Postal Code
89502
Country
United States
Facility Name
Cooper Hospital /University Medical Center
City
Camden
State/Province
New Jersey
ZIP/Postal Code
08103
Country
United States
Facility Name
JFK Medical Center
City
Edison
State/Province
New Jersey
ZIP/Postal Code
08818
Country
United States
Facility Name
Englewood Hospital and Medical Center
City
Englewood
State/Province
New Jersey
ZIP/Postal Code
07631
Country
United States
Facility Name
Virtua Memorial Hospital
City
Medford
State/Province
New Jersey
ZIP/Postal Code
08055
Country
United States
Facility Name
Robert Wood Johnson Hospital
City
New Brunswick
State/Province
New Jersey
ZIP/Postal Code
08901
Country
United States
Facility Name
Muhlenberg Hospital
City
Plainfield
State/Province
New Jersey
ZIP/Postal Code
07061
Country
United States
Facility Name
Valley Hospital
City
Ridgewood
State/Province
New Jersey
ZIP/Postal Code
08629
Country
United States
Facility Name
Overlook Hospital
City
Summit
State/Province
New Jersey
ZIP/Postal Code
07091
Country
United States
Facility Name
Community Medical Center
City
Toms River
State/Province
New Jersey
ZIP/Postal Code
08755
Country
United States
Facility Name
St. Francis Medical Center
City
Trenton
State/Province
New Jersey
ZIP/Postal Code
08629
Country
United States
Facility Name
St. Peter's Hospital
City
Albany
State/Province
New York
ZIP/Postal Code
12208
Country
United States
Facility Name
Buffalo General Hospital
City
Buffalo
State/Province
New York
ZIP/Postal Code
14203
Country
United States
Facility Name
Millard Fillmore Hospital
City
Buffalo
State/Province
New York
ZIP/Postal Code
14209
Country
United States
Facility Name
Wilson Memorial Regional Medical Center
City
Johnson City
State/Province
New York
ZIP/Postal Code
13790
Country
United States
Facility Name
North Shore University Hospital
City
Manhasset
State/Province
New York
ZIP/Postal Code
11030
Country
United States
Facility Name
Winthrop University Hospital
City
Mineola
State/Province
New York
ZIP/Postal Code
11501
Country
United States
Facility Name
Mount Vernon Hospital
City
Mount Vernon
State/Province
New York
ZIP/Postal Code
10550
Country
United States
Facility Name
Long Island Jewish Medical Center
City
New Hyde Park
State/Province
New York
ZIP/Postal Code
11040
Country
United States
Facility Name
Mt. Sinai Hospital
City
New York
State/Province
New York
ZIP/Postal Code
10029
Country
United States
Facility Name
Rochester General Hospital
City
Rochester
State/Province
New York
ZIP/Postal Code
14621
Country
United States
Facility Name
Strong Memorial Hospital
City
Rochester
State/Province
New York
ZIP/Postal Code
14642
Country
United States
Facility Name
Ellis Hospital Stroke Center B421
City
Schenectady
State/Province
New York
ZIP/Postal Code
12308
Country
United States
Facility Name
SUNY Stony Brook University Hospital
City
Stony Brook
State/Province
New York
ZIP/Postal Code
11794
Country
United States
Facility Name
University of North Carolina Hospital
City
Chapel Hill
State/Province
North Carolina
ZIP/Postal Code
27599
Country
United States
Facility Name
Rowan Regional Medical Center
City
Salisbury
State/Province
North Carolina
ZIP/Postal Code
28144
Country
United States
Facility Name
Forsyth Medical Center
City
Winston-Salem
State/Province
North Carolina
ZIP/Postal Code
27103
Country
United States
Facility Name
Akron General Medical Center
City
Akron
State/Province
Ohio
ZIP/Postal Code
44307
Country
United States
Facility Name
University Hospitals of Cleveland
City
Cleveland
State/Province
Ohio
ZIP/Postal Code
44106
Country
United States
Facility Name
Metrohealth Medical Center
City
Cleveland
State/Province
Ohio
ZIP/Postal Code
44109
Country
United States
Facility Name
Kettering Medical Center -Wallace Kettering Neuroscience Inst.
City
Kettering
State/Province
Ohio
ZIP/Postal Code
45429
Country
United States
Facility Name
Medical College of Ohio Hospital
City
Toledo
State/Province
Ohio
ZIP/Postal Code
43614
Country
United States
Facility Name
St. Elizabeth's Health Center
City
Youngstown
State/Province
Ohio
ZIP/Postal Code
44501
Country
United States
Facility Name
Rogue Valley Medical Center
City
Medford
State/Province
Oregon
ZIP/Postal Code
97504
Country
United States
Facility Name
Oregon Health and Science University - Oregon Stroke Center
City
Portland
State/Province
Oregon
ZIP/Postal Code
97201
Country
United States
Facility Name
Providence Portland Medical Center
City
Portland
State/Province
Oregon
ZIP/Postal Code
97213
Country
United States
Facility Name
Providence St. Vincent's Hospital
City
Portland
State/Province
Oregon
ZIP/Postal Code
97225
Country
United States
Facility Name
Lehigh Valley Hospital
City
Allentown
State/Province
Pennsylvania
ZIP/Postal Code
18103
Country
United States
Facility Name
Westmoreland Regional Hospital
City
Greensburg
State/Province
Pennsylvania
ZIP/Postal Code
15601
Country
United States
Facility Name
University of Pennsylvania Medical Center
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19104
Country
United States
Facility Name
Thomas Jefferson University Hospital
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19107
Country
United States
Facility Name
University of Pittsburg Medical Center
City
Pittsburg
State/Province
Pennsylvania
ZIP/Postal Code
15213
Country
United States
Facility Name
Crozer Chester Medical Center
City
Upland
State/Province
Pennsylvania
ZIP/Postal Code
19013
Country
United States
Facility Name
York Hospital
City
York
State/Province
Pennsylvania
ZIP/Postal Code
17402
Country
United States
Facility Name
Miriam Hospital
City
Providence
State/Province
Rhode Island
ZIP/Postal Code
02906
Country
United States
Facility Name
Greenville Hospital
City
Greenville
State/Province
South Carolina
ZIP/Postal Code
29615
Country
United States
Facility Name
Erlanger Hospital
City
Chattanooga
State/Province
Tennessee
ZIP/Postal Code
37403
Country
United States
Facility Name
Regional Medical Center at Memphis
City
Memphis
State/Province
Tennessee
ZIP/Postal Code
38103
Country
United States
Facility Name
Vanderbilt University Medical Center
City
Nashville
State/Province
Tennessee
ZIP/Postal Code
37232
Country
United States
Facility Name
Baylor University Medical Center
City
Dallas
State/Province
Texas
ZIP/Postal Code
75214
Country
United States
Facility Name
University of Texas; Southwestern Medical Center at Dallas
City
Dallas
State/Province
Texas
ZIP/Postal Code
75390
Country
United States
Facility Name
Methodist Hospital /Baylor College of Medicine
City
Houston
State/Province
Texas
ZIP/Postal Code
77030
Country
United States
Facility Name
The Methodist Hospital
City
Houston
State/Province
Texas
ZIP/Postal Code
77030
Country
United States
Facility Name
University Hospital /Univ of Texas Health Science Center
City
San Antonio
State/Province
Texas
ZIP/Postal Code
78229
Country
United States
Facility Name
University of Utah Medical Center
City
Salt Lake City
State/Province
Utah
ZIP/Postal Code
84132
Country
United States
Facility Name
The Innovative Clincal Research Center
City
Alexandria
State/Province
Virginia
ZIP/Postal Code
22304
Country
United States
Facility Name
Virginia Commonwealth University /Medical College of VA
City
Richmond
State/Province
Virginia
ZIP/Postal Code
23219
Country
United States
Facility Name
Henrico Doctors Hospital
City
Richmond
State/Province
Virginia
ZIP/Postal Code
23226
Country
United States
Facility Name
Memorial Regional Medical Center
City
Richmond
State/Province
Virginia
ZIP/Postal Code
23226
Country
United States
Facility Name
St. Mary's Hospital
City
Richmond
State/Province
Virginia
ZIP/Postal Code
23226
Country
United States
Facility Name
Harborview Medical Center
City
Seattle
State/Province
Washington
ZIP/Postal Code
98104
Country
United States
Facility Name
Charleston Area Medical Center
City
Charleston
State/Province
West Virginia
ZIP/Postal Code
25301
Country
United States
Facility Name
University of Wisconsin Hospitals and Clinics
City
Madison
State/Province
Wisconsin
ZIP/Postal Code
53792
Country
United States
Facility Name
St. Joseph's Hospital/ Marshfield Clinic
City
Marshfield
State/Province
Wisconsin
ZIP/Postal Code
54449
Country
United States
Facility Name
St. Luke's Medical Center
City
Milwaukee
State/Province
Wisconsin
ZIP/Postal Code
53215
Country
United States
Facility Name
Theda Clark Medical Center
City
Neenah
State/Province
Wisconsin
ZIP/Postal Code
54956
Country
United States
Facility Name
Foothills Medical Center /University of Calgary
City
Calgary
State/Province
Alberta
ZIP/Postal Code
T2N 2T9
Country
Canada
Facility Name
University of Alberta Hospital /Mackenzie Center
City
Edmonton
State/Province
Alberta
ZIP/Postal Code
T6G 2B7
Country
Canada
Facility Name
Lethbridge Regional Hospital
City
Lethbridge
State/Province
Alberta
ZIP/Postal Code
T1O 1W5
Country
Canada
Facility Name
Royal Inland Hospital
City
Kamloops
State/Province
British Columbia
ZIP/Postal Code
V2C 2T1
Country
Canada
Facility Name
Kelowna General Hospital
City
Kelowna
State/Province
British Columbia
ZIP/Postal Code
V1Y 1T2
Country
Canada
Facility Name
St Paul's Hospital
City
Vancouver
State/Province
British Columbia
ZIP/Postal Code
U6Z 2A5
Country
Canada
Facility Name
Vancouver General Hospital
City
Vancouver
State/Province
British Columbia
ZIP/Postal Code
V5Z 1M9
Country
Canada
Facility Name
Royal Jubilee Hospital
City
Victoria
State/Province
British Columbia
ZIP/Postal Code
V8R 4R2
Country
Canada
Facility Name
Kingston General Hospital
City
Kingston
State/Province
Ontario
ZIP/Postal Code
K7L 2V7
Country
Canada
Facility Name
London Health Sciences Centre
City
London
State/Province
Ontario
ZIP/Postal Code
N6A 5A5
Country
Canada
Facility Name
Trillium Health Centre
City
Mississauga
State/Province
Ontario
ZIP/Postal Code
L5B 4A2
Country
Canada
Facility Name
York Central Hospital
City
Richmond Hill
State/Province
Ontario
ZIP/Postal Code
L4C 9M7
Country
Canada
Facility Name
Complexe Hospitalier de La Sagamie
City
Chicoutimi
State/Province
Quebec
ZIP/Postal Code
G7H 5H6
Country
Canada
Facility Name
Centre Hospitalier des Vallees de l'Outaouais
City
Gatineau
State/Province
Quebec
ZIP/Postal Code
J8Y 1W7
Country
Canada
Facility Name
Hotel-Dieu de Levis
City
Levis
State/Province
Quebec
ZIP/Postal Code
G6V 3Z1
Country
Canada
Facility Name
Hospital Notre Dame du Chum
City
Montreal
State/Province
Quebec
ZIP/Postal Code
H2L 4M1
Country
Canada
Facility Name
Hotel-Dieu de St-Jerome
City
Saint-Jerome
State/Province
Quebec
ZIP/Postal Code
J7Z5T3
Country
Canada
Facility Name
Royal University Hospital
City
Saskatoon
State/Province
Saskatchewan
ZIP/Postal Code
S7N 0W8
Country
Canada
12. IPD Sharing Statement
Learn more about this trial
A Study to Evaluate the Effects of ONO-2506 Intravenous Infusion in Patients With Acute Ischemic Stroke
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