Chemotherapy Before and After Surgery in Treating Children With Wilm's Tumor
Kidney Cancer
About this trial
This is an interventional treatment trial for Kidney Cancer focused on measuring blastema predominant Wilms tumor, epithelial predominant Wilms tumor, mixed cell type Wilms tumor, stage I Wilms tumor, stage II Wilms tumor, stage III Wilms tumor, stage IV Wilms tumor, stage V Wilms tumor, stromal predominant Wilms tumor
Eligibility Criteria
DISEASE CHARACTERISTICS: Diagnosis of one of the following: Localized disease Unilateral tumor Histologically confirmed Wilms' tumor OR Clinical and ultrasonic characteristics of nephroblastoma No metastasis Age 6 months to 17 years at diagnosis No prior anticancer therapy Metastatic disease Unilateral tumor Histologically confirmed Wilms' tumor OR Clinical and ultrasonic characteristics of nephroblastoma Age 18 and under No prior anticancer therapy Simultaneous bilateral tumors No metastases No recurrent disease No other renal tumors PATIENT CHARACTERISTICS: Age See Disease Characteristics 18 and under Performance status Not specified Life expectancy Not specified Hematopoietic Not specified Hepatic Not specified Renal Not specified Other No social or geographical reasons that would preclude study No other associated pathology that would preclude study PRIOR CONCURRENT THERAPY: Biologic therapy Not specified Chemotherapy No prior chemotherapy Endocrine therapy Not specified Radiotherapy No prior radiotherapy Surgery No prior surgery No requirement for emergency or immediate surgery for any reason
Sites / Locations
- Institut Gustave RoussyRecruiting
- Universitaetsklinikum des SaarlandesRecruiting
- Academisch Medisch Centrum at University of AmsterdamRecruiting
- Royal Marsden - SurreyRecruiting