Pediatric Epilepsy Study

INCLUSION CRITERIA: To enter this study, patients must: Have a diagnosis of partial seizures Be willing to be hospitalized Weigh a minimum of 6.6 pounds Be taking a stable dose of one to two concomitant anti-epileptic medications Have had a previous CAT scan/MRI confirming the absence of space occupying lesions or progressive neurological disease Have normal laboratory results EXCLUSION CRITERIA: To enter this study, a patient must not have or be: Seizures caused by metabolic disturbance, toxic exposure, or active infection A primary diagnosis of generalized epilepsy (exception - secondarily generalized seizures) A history of status epilepticus within 30 days Seizures not related to epilepsy Frequent use of additional anti-epileptic medications to treat increases in seizures (for example: rectal diazepam) Taking felbamate within 6 months Serum sodium levels <135 mEq/L Significant heart, breathing, kidney, stomach, liver, blood, or cancer disorder requiring treatment/therapy A history of chronic infection (e.g., hepatitis or HIV) Significant electrocardiogram (ECG) abnormalities A nursing mother taking anti-convulsant drugs Previously demonstrated sensitivity/allergic reaction to Trileptal or related compounds Used experimental medication within 30 days of entering this study