S0224, Docetaxel in Treating Patients With Locally Advanced or Metastatic Penile Cancer (TERMINATED)
Penile Cancer
About this trial
This is an interventional treatment trial for Penile Cancer focused on measuring stage II penile cancer, stage III penile cancer, stage IV penile cancer
Eligibility Criteria
DISEASE CHARACTERISTICS: Histologically confirmed epidermoid carcinoma of the penis Distant metastases (M1) OR Pathologically confirmed regional nodal metastases (N1-3) Measurable disease Soft tissue disease irradiated within the past 2 months is not considered measurable disease PATIENT CHARACTERISTICS: Age Not specified Performance status Zubrod 0-2 Life expectancy Not specified Hematopoietic White blood cell (WBC) count at least 3,000/mm^3 Absolute granulocyte count at least 1,500/mm^3 Platelet count at least 100,000/mm^3 Hepatic Bilirubin no greater than upper limit of normal (ULN) Aspartate aminotransferase (SGOT) no greater than 2.5 times ULN If SGOT is greater than ULN, alkaline phosphatase must be no greater than 2.5 times ULN Alkaline phosphatase no greater than 4 times ULN If alkaline phosphatase is greater than ULN, SGOT must be no greater than 1.5 times ULN Renal Not specified Other Fertile patients must use effective contraception No other malignancy within the past 5 years except adequately treated basal cell or squamous cell skin cancer or stage I or II cancer currently in complete remission No grade 2 or greater peripheral neuropathy No hypersensitivity to drugs formulated with polysorbate 80 (e.g., recombinant interferon alfa-2a, multivitamin infusion, etoposide, infliximab, or NovoSeven factor) PRIOR CONCURRENT THERAPY: Biologic therapy Not specified Chemotherapy No prior chemotherapy for penile cancer Endocrine therapy Not specified Radiotherapy See Disease Characteristics At least 28 days since prior radiotherapy and recovered Surgery Not specified
Sites / Locations
- St. Anthony Central Hospital
- University of Colorado Cancer Center at University of Colorado Health Sciences Center
- Veterans Affairs Medical Center - Denver
- Montrose Memorial Hospital Cancer Center
- St. Anthony North Hospital
- Exempla Lutheran Medical Center
- Salina Regional Health Center
- University of Michigan Comprehensive Cancer Center
- CCOP - Montana Cancer Consortium
- Deaconess Billings Clinic - Downtown
- Northern Rockies Radiation Oncology Center
- St. Vincent Healthcare
- Deaconess Billings Clinic Cancer Center
- Bozeman Deaconess Hospital
- St. James Community Hospital
- St. Peter's Hospital
- Kalispell Regional Medical Center
- Eastern Montana Cancer Center
- Community Medical Center
- Montana Cancer Center at St. Patrick Hospital and Health Sciences Center
- Wayne Memorial Hospital, Incorporated
- Rutherford Hospital
- Wilson Medical Center
- Adena Regional Medical Center
- Cleveland Clinic Taussig Cancer Center
- Riverside Methodist Hospital Cancer Care
- CCOP - Columbus
- Grant Riverside Cancer Services
- Mount Carmel West Hospital
- Doctors Hospital at Ohio Health
- Grady Memorial Hospital
- Community Oncology Group - Independence
- Fairfield Medical Center
- Strecker Cancer Center at Marietta Memorial Hospital
- Licking Memorial Cancer Care Program at Licking Memorial Hospital
- Mercy Medical Center Oncology Unit
- Community Hospital of Springfield and Clark County
- Mount Carmel Cancer Services at Mount Carmel St. Ann's Hospital
- Cleveland Clinic - Wooster
- Genesis - Good Samaritan Hospital
- Oklahoma University Medical Center
- Cancer Institute at Oregon Health and Science University
- Rose Ramer Cancer Clinic at Anderson Area Medical Center
- Gibbs Regional Cancer Center at Spartanburg Regional Medical Center
- CCOP - Upstate Carolina
- Sioux Valley Hospital and University of South Dakota Medical Center
- Avera McKennan Hospital and University Health Center
- Medical X-Ray Center
- Welch Cancer Center