Liposomal Doxorubicin and Thermal Therapy in Treating Patients With Prostate Cancer

DISEASE CHARACTERISTICS: Histologically confirmed adenocarcinoma of the prostate Rising prostate-specific antigen AND radiographic evidence of extraprostatic prostate cancer by bone scan, CT scan, prostascint scan, or MRI PATIENT CHARACTERISTICS: Age 40 and over Performance status Karnofsky 80-100% Life expectancy Not specified Hematopoietic WBC greater than 4,000/mm^3 Platelet count greater than 100,000/mm^3 Hemoglobin greater than 10.0 g/dL Hepatic Bilirubin normal AST normal Alkaline phosphatase normal No acute or chronic liver disease Renal Creatinine less than 1.5 times upper limit of normal Cardiovascular Ejection fraction at least 50% by MUGA EKG normal No myocardial infarction or cerebral vascular accident within the past 6 months No life threatening cardiac arrhythmias No congestive heart failure No cardiac pacemaker No peripheral arterial disease with intermittent claudication or Leriches syndrome (i.e., claudication of the buttocks or perineum) Other Fertile patients must use effective barrier contraception during and for 3 months after study participation No sperm donation during and for 3 months after study participation Not febrile No interest in future fertility or fathering children No significantly decreased pain response No severe urethral stricture No protruding median lobe resulting in a "ball-valve" type of obstruction at the bladder neck No major psychiatric illness that would prevent informed consent No major psychiatric illness that required inpatient treatment within the past 3 months No psychological, family, sociological, or geographic condition that would preclude study compliance No allergy to eggs or egg products No urinary or prostatic infection No full urinary retention No penile or urinary sphincter implant No metallic implants in the pelvic or femoral area No other serious medical illness that would preclude study participation PRIOR CONCURRENT THERAPY: Biologic therapy No concurrent live vaccines Chemotherapy No prior anthracycline No concurrent streptozocin Endocrine therapy No concurrent hormonal therapy (except luteinizing hormone-releasing hormone analog) No concurrent glucocorticoids administered at more than physiologic replacement doses (other than as an antiemetic) Radiotherapy Not specified Surgery More than 3 months since prior major surgery Other No prior therapy that resulted in permanent reduction of pain response (e.g., prior surgery, regional or local anesthetic) No concurrent PC-SPES No concurrent cyclosporine, phenobarbital, or phenytoin