SR34006 Compared to Vitamin K Antagonist (VKA) in the Treatment of Pulmonary Embolism
Pulmonary Embolism
About this trial
This is an interventional treatment trial for Pulmonary Embolism
Eligibility Criteria
Inclusion Criteria: Confirmed acute symptomatic Pulmonary Embolism (PE) with or without concomitant Deep Vein Thrombosis (DVT) Written informed consent Exclusion Criteria: Legal lower age limitations (country specific) Thrombectomy, insertion of a caval filter, or use of a fibrinolytic agent to treat the current episode of PE Other indication for VKA than PE/DVT More than 36 hours pre-randomization treatment with therapeutic dosages of (LMW)heparin or initiation of VKA treatment prior to randomization Participation in another pharmacotherapeutic study within the prior 30 days Creatinine clearance <10 mL/min, severe hepatic disease, or bacterial endocarditis Life expectancy <3 months Active bleeding or high risk for bleeding Uncontrolled hypertension: systolic blood pressure >180 mm Hg or diastolic blood pressure >110 mm Hg Pregnancy or childbearing potential without proper contraceptive measures or women who are breastfeeding Any other contraindication listed in the labeling of warfarin, acenocoumarol, unfractionated heparin, enoxaparin, or tinzaparin
Sites / Locations
- Jerry L. Pettic VA Medical Center
- University of California, San Diego Medical Center
- Anschutz Cancer Pavilion
- University of Colorado Hospital
- Bay Pines VA Medical Center
- Brandon Regional Hospital
- Holmes Regional Medical Center
- Jackson Memorial Hospital
- St. Joseph's Hospital
- Medical College of Georgia
- DeKalb Medical Center
- Loyola University Medical Center and Outpatient Clinic
- Olathe Medical Center
- Christus St. Patrick Hospital
- Sinai Hospital of Baltimore
- Boston Medical Center
- Baystate Medical Center
- Henry Ford Hospital
- St. Joseph Mercy - Oakland
- William Beaumont Hospital
- William Beaumont Hospital
- Lovelace Health Systems, Clinical Thrombosis Center
- Winthrop Pulmonary Associates
- Winthrop University Hospital
- Mount Sinai School of Medicine
- St. Luke's-Roosevelt Hospital Center
- University of North Carolina Hospitals
- Altru Health System Hospital
- Akron General Medical Center
- Riverside Methodist Hospital
- Medical College of Ohio
- Saint Anthony Hospital
- Oklahoma City VA Medical Center
- OU Medical Center
- INTEGRIS Southwest Medical Center
- Lehigh Valley Hospital
- Crozer-Chester Medical Center
- Spartanburg Regional Medical Center
- Mary Black Memorial Hospital
- Baptist Memorial Hospital Memphis
- The West Cancer Clinic
- Northwest Texas Healthcare System
- The Methodist Hospital
- Scott & White Memorial Hospital & Clinic
- The University of Texas Health Center at Tyler
- University Hospital
- Inova Alexandria Hospital
- MedSource, Inc.
- Portsmouth Pulmonary Associates
- Pulmonary Associates of Fredericksburg, Inc.
- Maryview Medical Center
- McGuire VA Medical Center
- Swedish Medical Center
- Sacred Heart Medical Center
- University of Alberta Hospital
- Kelowna General Hospital
- St. Paul's Hospital
- St. Boniface General Hospital
- QEII Health Sciences Center
- Hamilton Health Sciences - General Hospital
- London Health Sciences Centre
- Ottawa Hospital - Civic Campus
- University Health Network, Toronto General Hospital
- Humber River Regional Hospital
- Jewish General Hospital
- Hotel-Dieu de St-Jerome