Preventing Post-Stroke Depression
Depression, Cerebrovascular Accident
About this trial
This is an interventional prevention trial for Depression focused on measuring Stroke
Eligibility Criteria
Inclusion Criteria: Stroke within the last 120 days Exclusion Criteria: DSM (Diagnostic and Statistical Manual) IV criteria for major or minor depressive disorder Heart, respiratory, kidney, or liver failure; severely disabling musculoskeletal disorder; or cancer Diagnosis of neurodegenerative disorders such as Parkinson's disease, Alzheimer's disease, Multiple System Atrophy, or Huntington's disease Pre-existing dementia or aphasia with severe language comprehension deficits Alcohol or substance abuse or dependence within the last 12 months Recurrent unipolar or bipolar disorder prior to the stroke
Sites / Locations
- University of Chicago
- University of Iowa Hospitals and Clinics
- Burke Rehabilitation Hospital
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Experimental
Placebo Comparator
1 Problem Solving Therapy
2. Escitalopram
3 Placebo
Participants will receive problem solving therapy.
Participants will receive escitalopram.
Participants will receive placebo.