Dobutamine Echocardiography In Patients With Ischemic Heart Failure Evaluated for Revascularization (DECIPHER)
Cardiovascular Diseases, Coronary Disease, Heart Failure
About this trial
This is an interventional diagnostic trial for Cardiovascular Diseases
Eligibility Criteria
Enrollment Requirements Inclusion Criteria: Symptomatic heart failure defined as NYHA Class II - IV (within 3 months of entry) LV less than 35% defined by CMR or gated SPECT studies Coronary anatomy suitable for revascularization Exclusion Criteria: Primary valvular heart disease clearly defined indicating the need for valve repair or replacement Patients with concurrent cardiogenic shock or requiring inotropic or intra-aortic balloon support PCI planned for CAD treatment Acute myocardial infarction within 30 days More than one prior cardiac operation Non-cardiac illness with life expectancy of less than 3 years Non-cardiac illness imposing substantial operative mortality. Patients eligible to enter the study will be further evaluated by the STICH team for SVR eligibility.
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
Medical Therapy
CABG
All medical interventions know to improve outcomes in patients with ischemic left ventricular dysfunction.
Surgical revascularization in conjunction with optimal medical therapy.