Magnetic Resonance Imaging to Locate and Characterize Prostate Cancer
Prostate Cancer
About this trial
This is an interventional diagnostic trial for Prostate Cancer focused on measuring MRI, Biopsy, Fiducial Marker, Prostate Cancer
Eligibility Criteria
INCLUSION CRITERIA: ECOG performance status 0 or 1. Patients with a TRUS-guided biopsy for suspected prostate cancer in the past twelve months, or patients with pathologically confirmed adenocarcinoma of the prostate gland and who have not received definitive local therapy. Age greater than or equal to 18 years. Informed consent: All patients must sign a document of informed consent indicating their understanding of the investigational nature and risks of the study before any protocol related studies are performed. EXCLUSION CRITERIA: Contraindication to trans-rectal biopsy: Bleeding disorder; PT/PTT greater than or equal to 1.5 times the upper limit of normal; Platelets less than or equal to 50K; Active anticoagulation; Severe immunocompromise; Severe hemorrhoids; Surgically absent rectum. Contraindication to MRI: Patients weighing greater than 136 kgs (weight limit for the scanner tables); Allergy to MR contrast agent; Patients with pacemakers, cerebral aneurysm clips, shrapnel injury or implantable electronic devices not compatible with MRI. Allergy to local anesthetics or quinolone antibiotics. Patients with a known diagnosis of prostate cancer and a known treatment plan to proceed to prostatectomy if the result of the biopsy would not affect surgical management. Other medical conditions deemed by the PI or associates to make the patient ineligible for protocol procedures.
Sites / Locations
- National Institutes of Health Clinical Center, 9000 Rockville Pike
Arms of the Study
Arm 1
Experimental
Biopsy
Biopsy