Serotonin Transporters in Obsessive-Compulsive-Related Disorders
Obsessive-Compulsive Disorder
About this trial
This is an observational trial for Obsessive-Compulsive Disorder focused on measuring Genetics, Serotonin Transporter, Brain Imaging, Neurotransmitter, OCD, Obsessive-Compulsive Disorder, PET, Obsessive Compulsive Disorder, Healthy Volunteer, HV
Eligibility Criteria
INCLUSION CRITERIA: Patients and Controls: Age: 18-65. Patients- DSM-IV criteria for OCD. Controls- not required Patients and Controls: Good health, with absence of serious medical illnesses, such as congestive heart failure, diabetes, kidney failure, epilepsy or cancer. EXCLUSION CRITERIA: Healthy Subjects: History or current DSM-IV Axis I diagnostic criteria. Patients and Controls: Current diagnosis of major depressive disorder. Patients and Controls: Psychotropic medications, including SSRIs and antipsychotic medications. Drug free period must be greater than 4 weeks. Patients and Controls: Claustrophobia Patients and Controls: Pregnancy. Women with child bearing potential. Patients and Controls: Prior participation in other research protocols within the past year such that a radiation exposure together with the present study would exceed the annual limits. Patients and Controls: Any condition that increases risk for MRI (e.g., pacemaker, metallic foreign body in the eye, etc.)
Sites / Locations
- National Institutes of Health Clinical Center, 9000 Rockville Pike