Genetic and Protein Profiling in Normal and Cancerous Breast Tissue
Breast Neoplasms
About this trial
This is an observational trial for Breast Neoplasms focused on measuring Gene Expression, Microarray, Stem Cell, Proteomics, Metastases, Breast Tissue, Normal Breast Tissue, Breast Cancer
Eligibility Criteria
INCLUSION CRITERIA: Subjects of any age who are undergoing cosmetic breast surgery that entails resection of breast tissue (e.g., reduction mammoplasty) for any reason. Women (18 years of age or older) with known or suspected breast cancer who are undergoing a diagnostic biopsy or resection of a primary breast lesions or a site of metastatic tumor. Women (18 years of age or older) with breast cancer who are undergoing a pleurocentesis for removal of fluid from a known or suspected malignant pleural effusion. All patients or their legal guardians (if the patient is less than 18 years of age) must sign a document of informed consent indicating their understanding that the specimens collected and demographic information provided is only for research purposes. Written assent will be obtained from pediatric patients (less than 18 years of age). EXCLUSION CRITERIA: 1. Subjects who are undergoing cosmetic breast procedures such as reduction mammoplasty (collection of normal breast tissue) are excluded if they have a prior history of breast cancer.
Sites / Locations
- National Institutes of Health Clinical Center, 9000 Rockville Pike