Monotherapy Study in Patients With Type 2 Diabetes Mellitus (0431-021)

Inclusion Criteria: Patients with type 2 diabetes mellitus Patient is not pregnant or breastfeeding Male or female patient unlikely to conceive Patient not on an antihyperglycemic drug Exclusion Criteria: Patient has history of type 1 diabetes mellitus Patient has history of ketoacidosis Patient requires insulin within 8 weeks prior to start of study Patient on weight loss program and is not in maintenance phase Patient taking weight loss medication within 8 weeks prior to start of study Patient on or likely to require = 14 days or repeated courses of corticosteroids Patient taking immunosuppressive/immunomodulating medication Patient taking digoxin or other cardiac medication Patient has undergone surgical general anesthesia within 30 days prior to start of study Patient taking investigational drug within 8 weeks prior to start of study Patient is diagnosed with liver disease Patient has chronic myopathy, progressive neurological/neuromuscular disorder Patient has with severe cardiac conditions within the last 6 months Patient is Human immunodeficiency virus (HIV) positive Patient has hematological disorder Patient has history of malignancy Patient has history of alcohol or drug abuse within the past 3 years