Effectiveness of Depression Treatment Following Coronary Artery Bypass Surgery
Cardiovascular Diseases, Coronary Disease, Heart Diseases

About this trial
This is an interventional treatment trial for Cardiovascular Diseases
Eligibility Criteria
Inclusion Criteria: Recently underwent CABG (combined or redo procedure) at one of 8 Pittsburgh area study hospitals A PHQ score greater than 10 OR if nondepressed control, a PHQ score less than 5 at both 2 days post CABG to the date of discharge following CABG and when reassessed 2 weeks after hospital discharge Folstein Mini-Mental State Examination (MMSE) score greater than or equal to 24 Able to be evaluated and treated for depression as an outpatient post CABG Has a household telephone Exclusion Criteria: Presently in treatment with a mental health specialist Actively suicidal History of psychotic illness History of bipolar illness according to subject self-report and past medical history Current alcohol dependence or other substance abuse as evidenced by chart review and the CAGE questionnaire Organic mood syndromes, including those secondary to medical illness or drugs Presence of non-cardiovascular conditions that are likely to be fatal within 1 year Unstable medical condition as indicated by history, physical, and/or laboratory findings Previous enrollment in the study cohort Non-English speaking, illiterate, or possessing any other communication barrier If nondepressed control, current or previous diagnosis or treatment of depression
Sites / Locations
- University of Pittsburgh School of Medicine
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Active Comparator
No Intervention
Depressed Intervention
Depressed Usual Care
Non-Depressed Control Group
Telephone-based, nurse-delivered Collaborative Care program for depression; Involving: Psychoeducation; workbook for depression self-care; initiation or adjustment of antidepressant pharmacotherapy prescribed under their PCPs' direction; referral to mental health specialist
"Usual care" for depression; feedback of the depression finding by the study team
Non-depressed control group