Lycopene in Preventing Prostate Cancer in Healthy Participants

DISEASE CHARACTERISTICS: Healthy participants in good medical condition No chronic medical conditions No regular use of prescription medications No evidence of psychiatric disorder Non-smoker Former smokers allowed provided they have not smoked within the past 3 months No history of alcohol abuse Serum lycopene concentration < 700 nM PATIENT CHARACTERISTICS: Age 18 to 45 Performance status Karnofsky 100% Life expectancy Not specified Hematopoietic Hemoglobin ≥ 13.0 g/dL WBC ≥ 4,000/mm^3 Platelet count 150,000-400,000/mm^3 Hepatic AST and ALT ≤ 75 U/L Bilirubin ≤ 2.0 mg/dL No liver disease Renal Creatinine ≤ 1.5 mg/dL No renal disease Cardiovascular No cardiovascular disease No abnormal EKG Other Within 15% of ideal body weight No history of gastrointestinal malabsorption or other condition that would preclude drug absorption No alcohol consumption within the past 72 hours No allergy to tomato-based products No history of cancer No diabetes mellitus No other illness that would preclude study participation PRIOR CONCURRENT THERAPY: Biologic therapy Not specified Chemotherapy Not specified Endocrine therapy Not specified Radiotherapy Not specified Surgery Not specified Other At least 4 weeks since prior experimental drugs More than 14 days since prior prescription drugs No concurrent participation in another experimental trial No concurrent prescription drugs