A Treatment Protocol for Patients With Gastrointestinal Stromal Tumor (GIST) Who May Derive Benefit From Treatment With SU011248
Gastrointestinal Neoplasm
About this trial
This is an expanded access trial for Gastrointestinal Neoplasm
Eligibility Criteria
Inclusion Criteria: Histologically proven Gastrointestinal Stomal Tumor (GIST) that is not amenable to standard therapy Undergone screening and found to be ineligible for participation in ongoing SU011248 clinical studies Patient judged to have potential to derive clinical benefit from SU011248 treatment by the treating physician Failed prior treatment with imatinib mesylate, defined as either progression of disease or significant toxicity during treatment with imatinib mesylate that precluded further treatment Male or Female, 18 years or older Resolution of all acute toxicities of prior therapies Adequate organ function Exclusion Criteria: Symptomatic congestive heart failure, myocardial infarction, or coronary artery bypass graft in the last 6 months, or ongoing severe or unstable angina or any unstable arrhythmia requiring medication Symptomatic central nervous system metastases Serious acute or chronic illness Current treatment on another clinical trial Pregnant or breastfeeding.
Sites / Locations
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