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Carboplatin in Treating Patients With Stage IC-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Primary Purpose

Fallopian Tube Cancer, Ovarian Cancer, Primary Peritoneal Cavity Cancer

Status
Completed
Phase
Phase 3
Locations
International
Study Type
Interventional
Intervention
carboplatin
Sponsored by
NHS Greater Glasgow and Clyde
About
Eligibility
Locations
Outcomes
Full info

About this trial

This is an interventional treatment trial for Fallopian Tube Cancer focused on measuring stage I ovarian epithelial cancer, stage II ovarian epithelial cancer, stage III ovarian epithelial cancer, stage IV ovarian epithelial cancer, fallopian tube cancer, primary peritoneal cavity cancer

Eligibility Criteria

18 Years - undefined (Adult, Older Adult)FemaleDoes not accept healthy volunteers

DISEASE CHARACTERISTICS: Histologically confirmed ovarian epithelial, fallopian tube, or primary peritoneal cancer* Stage IC-IV disease Peritoneal carcinomatosis* (ovarian-type) must not be a mucin-secreting tumor Stage IC patients must have malignant cells in ascitic fluid or peritoneal washings, tumor on the surface of the ovary, or preoperative capsule rupture NOTE: * Histologic confirmation of a primary source in the ovary is not required. If biospy is not available, cytology showing an adenocarcinoma is allowed provided the following criteria is met: Patient has a pelvis (ovarian) mass AND all of the following: Omental cake or other metastasis is larger than 2 cm in the upper abdomen and/or regional lymph node metastasis irrespective of size OR stage IV disease Serum CA 125/CEA ratio > 25 or barium enema (or colonoscopy) and gastroscopy (or radiological examination of the stomach) are negative for the presence of a primary tumor and normal mammography within 6 weeks prior to study randomization Initial cytoreductive laparotomy or biopsy required within the past 8 weeks Cytoreductive surgery may or may not have been successful during staging laparotomy No mixed mesodermal tumors No borderline ovarian tumors or tumors termed "possibly malignant" No adenocarcinoma of unknown origin, if histologically confirmed to be a mucin-secreting tumor Considered unsuitable for or unwilling to receive platinum-taxane combination therapy No concurrent endometrial cancer PATIENT CHARACTERISTICS: Age 18 and over Performance status ECOG 0-3 Life expectancy Not specified Hematopoietic Absolute neutrophil count ≥ 1,500/mm^3 Platelet count ≥ 100,000/mm^3 Hepatic Bilirubin normal AST and ALT ≤ 2.5 times upper limit of normal (ULN) Alkaline phosphatase ≤ 5 times ULN Renal Creatinine clearance ≥ 30 mL/min Obstructive hydronephrosis as a cause of borderline (i.e., creatinine clearance 30-45 mL/min) renal function must be treated before study entry Cardiovascular No hypertension No ischemic heart disease No myocardial infarction within the past 6 months No congestive heart failure Other Not pregnant or nursing Fertile patients must use effective contraception No symptomatic peripheral neuropathy ≥ grade 2 No uncontrolled infection No other severe and/or uncontrolled medical condition No other malignancy within the past 5 years except curatively treated carcinoma in situ of the cervix or basal cell skin cancer PRIOR CONCURRENT THERAPY: Biologic therapy Not specified Chemotherapy No prior chemotherapy No other concurrent cytotoxic chemotherapy until progressive disease occurs Endocrine therapy Not specified Radiotherapy No prior radiotherapy Surgery See Disease Characteristics

Sites / Locations

  • Sydney Heamatology and Oncology Clinics
  • Lismore Base Hospital
  • Institute of Oncology at Prince of Wales Hospital
  • Royal North Shore Hospital
  • Sydney Cancer Centre at Royal Prince Alfred Hospital
  • Tamworth Base Hospital
  • Manning Base Hospital
  • Newcastle Mater Misericordiae Hospital
  • Westmead Institute for Cancer Research at Westmead Hospital
  • Royal Brisbane and Women's Hospital
  • Townsville Hospital
  • Mater Adult Hospital
  • Flinders Medical Centre
  • Royal Hobart Hospital
  • Ballarat Oncology and Haematology Services
  • Box Hill Hospital
  • Royal Women's Hospital
  • Monash Medical Center - Clayton Campus
  • Frankston Hospital
  • Mercy Hospital for Women
  • Murray Valley Private Hospital and Cancer Treatment Centre
  • Auckland City Hospital
  • Christchurch Hospital
  • Waikato Hospital
  • Wellington Cancer Centre
  • Furness General Hospital
  • Royal United Hospital
  • Birmingham Heartlands Hospital
  • Royal Blackburn Hospital
  • Blackpool Victoria Hospital
  • Bradford Royal Infirmary
  • Sussex Cancer Centre at Royal Sussex County Hospital
  • Bristol Haematology and Oncology Centre
  • Broomfield Hospital
  • Queen's Hospital
  • Cheltenham General Hospital
  • Essex County Hospital
  • Walsgrave Hospital
  • Derbyshire Royal Infirmary
  • Dorset County Hospital
  • Russells Hall Hospital
  • Gloucestershire Royal Hospital
  • Hereford Hospitals NHS Trust
  • Huddersfield Royal Infirmary
  • Ipswich Hospital
  • Airedale General Hospital
  • Royal Lancaster Infirmary
  • Leeds Cancer Centre at St. James's University Hospital
  • Leicester Royal Infirmary
  • Liverpool Women's Hospital
  • Saint Bartholomew's Hospital
  • University College of London Hospitals
  • Guy's Hospital
  • St. Georges, University of London
  • Hammersmith Hospital
  • Mid Kent Oncology Centre at Maidstone Hospital
  • Christie Hospital
  • Queen Elizabeth The Queen Mother Hospital
  • Clatterbridge Centre for Oncology
  • Northampton General Hospital NHS Trust
  • Mount Vernon Cancer Centre at Mount Vernon Hospital
  • Kings Mill Hospital
  • Nottingham City Hospital NHS Trust
  • George Eliot Hospital
  • Whiston Hospital
  • Rosemere Cancer Centre at Royal Preston Hospital
  • Alexandra Healthcare NHS
  • Cancer Research Centre at Weston Park Hospital
  • Wexham Park Hospital
  • Royal Marsden - Surrey
  • Taunton and Somerset Hospital
  • South Warwickshire Hospital
  • Southend University Hospital NHS Foundation Trust
  • Weston General Hospital
  • Worcester Royal Hospital
  • Worthing Hospital
  • Yeovil District Hospital
  • Centre for Cancer Research and Cell Biology at Queen's University Belfast
  • Aberdeen Royal Infirmary
  • Dumfries & Galloway Royal Infirmary
  • Ninewells Hospital
  • Edinburgh Cancer Centre at Western General Hospital
  • Gartnavel General Hospital
  • Raigmore Hospital
  • Ysbyty Gwynedd
  • Velindre Cancer Center at Velindre Hospital
  • West Wales General Hospital
  • South West Wales Cancer Institute

Outcomes

Primary Outcome Measures

Progression-free survival

Secondary Outcome Measures

Toxicity
Quality of life
Clinical overall response rate and CA125 response
Overall survival

Full Information

First Posted
December 8, 2004
Last Updated
August 6, 2013
Sponsor
NHS Greater Glasgow and Clyde
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1. Study Identification

Unique Protocol Identification Number
NCT00098878
Brief Title
Carboplatin in Treating Patients With Stage IC-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Official Title
SCOTROC 4: A Prospective, Multicentre, Randomised Trial Of Carboplatin Flat Dosing Vs Intrapatient Dose Escalation In First Line Chemotherapy Of Ovarian, Fallopian Tube And Primary Peritoneal Cancers
Study Type
Interventional

2. Study Status

Record Verification Date
July 2009
Overall Recruitment Status
Completed
Study Start Date
March 2004 (undefined)
Primary Completion Date
July 2010 (Actual)
Study Completion Date
July 2010 (Actual)

3. Sponsor/Collaborators

Name of the Sponsor
NHS Greater Glasgow and Clyde

4. Oversight

5. Study Description

Brief Summary
RATIONALE: Drugs used in chemotherapy, such as carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. PURPOSE: This randomized phase III trial is comparing different doses of carboplatin to see how well they work in treating patients with stage IC, stage II, stage III, or stage IV ovarian, fallopian tube, or primary peritoneal cancer.
Detailed Description
OBJECTIVES: Primary Compare progression-free survival of patients with stage IC-IV ovarian epithelial, fallopian tube, or primary peritoneal cancer treated with flat-dose vs intra-patient dose-escalated carboplatin as first-line chemotherapy. Secondary Compare the toxic effects of these regimens in these patients. Compare the quality of life of patients treated with these regimens. Compare overall clinical response rate and CA 125 response in patients treated with these regimens. Compare overall survival of patients treated with these regimens. OUTLINE: This is a randomized, multicenter study. Patients are randomized to 1 of 2 treatment arms. Arm I: Patients receive a flat dose of carboplatin on day 1. Arm II: Patients receive intra-patient dose-escalated carboplatin on day 1. In both arms, treatment repeats every 21 days for up to 6 courses in the absence of disease progression or unacceptable toxicity. Quality of life is assessed at baseline, before each treatment course, and then at 2 months post-chemotherapy. Patients are followed every 2 months for 2 years, every 3 months for 1 year, every 4 months for 1 year, and then every 6 months thereafter. Peer Reviewed and Funded or Endorsed by Cancer Research UK PROJECTED ACCRUAL: A total of 1,300 patients (650 per treatment arm) will be accrued for this study.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Fallopian Tube Cancer, Ovarian Cancer, Primary Peritoneal Cavity Cancer
Keywords
stage I ovarian epithelial cancer, stage II ovarian epithelial cancer, stage III ovarian epithelial cancer, stage IV ovarian epithelial cancer, fallopian tube cancer, primary peritoneal cavity cancer

7. Study Design

Primary Purpose
Treatment
Study Phase
Phase 3
Allocation
Randomized
Enrollment
1300 (Anticipated)

8. Arms, Groups, and Interventions

Intervention Type
Drug
Intervention Name(s)
carboplatin
Primary Outcome Measure Information:
Title
Progression-free survival
Secondary Outcome Measure Information:
Title
Toxicity
Title
Quality of life
Title
Clinical overall response rate and CA125 response
Title
Overall survival

10. Eligibility

Sex
Female
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
DISEASE CHARACTERISTICS: Histologically confirmed ovarian epithelial, fallopian tube, or primary peritoneal cancer* Stage IC-IV disease Peritoneal carcinomatosis* (ovarian-type) must not be a mucin-secreting tumor Stage IC patients must have malignant cells in ascitic fluid or peritoneal washings, tumor on the surface of the ovary, or preoperative capsule rupture NOTE: * Histologic confirmation of a primary source in the ovary is not required. If biospy is not available, cytology showing an adenocarcinoma is allowed provided the following criteria is met: Patient has a pelvis (ovarian) mass AND all of the following: Omental cake or other metastasis is larger than 2 cm in the upper abdomen and/or regional lymph node metastasis irrespective of size OR stage IV disease Serum CA 125/CEA ratio > 25 or barium enema (or colonoscopy) and gastroscopy (or radiological examination of the stomach) are negative for the presence of a primary tumor and normal mammography within 6 weeks prior to study randomization Initial cytoreductive laparotomy or biopsy required within the past 8 weeks Cytoreductive surgery may or may not have been successful during staging laparotomy No mixed mesodermal tumors No borderline ovarian tumors or tumors termed "possibly malignant" No adenocarcinoma of unknown origin, if histologically confirmed to be a mucin-secreting tumor Considered unsuitable for or unwilling to receive platinum-taxane combination therapy No concurrent endometrial cancer PATIENT CHARACTERISTICS: Age 18 and over Performance status ECOG 0-3 Life expectancy Not specified Hematopoietic Absolute neutrophil count ≥ 1,500/mm^3 Platelet count ≥ 100,000/mm^3 Hepatic Bilirubin normal AST and ALT ≤ 2.5 times upper limit of normal (ULN) Alkaline phosphatase ≤ 5 times ULN Renal Creatinine clearance ≥ 30 mL/min Obstructive hydronephrosis as a cause of borderline (i.e., creatinine clearance 30-45 mL/min) renal function must be treated before study entry Cardiovascular No hypertension No ischemic heart disease No myocardial infarction within the past 6 months No congestive heart failure Other Not pregnant or nursing Fertile patients must use effective contraception No symptomatic peripheral neuropathy ≥ grade 2 No uncontrolled infection No other severe and/or uncontrolled medical condition No other malignancy within the past 5 years except curatively treated carcinoma in situ of the cervix or basal cell skin cancer PRIOR CONCURRENT THERAPY: Biologic therapy Not specified Chemotherapy No prior chemotherapy No other concurrent cytotoxic chemotherapy until progressive disease occurs Endocrine therapy Not specified Radiotherapy No prior radiotherapy Surgery See Disease Characteristics
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Stanley B. Kaye, MD, FRCP
Organizational Affiliation
Royal Marsden NHS Foundation Trust
Official's Role
Study Chair
Facility Information:
Facility Name
Sydney Heamatology and Oncology Clinics
City
Hornsby
State/Province
New South Wales
ZIP/Postal Code
2077
Country
Australia
Facility Name
Lismore Base Hospital
City
Lismore
State/Province
New South Wales
ZIP/Postal Code
2480
Country
Australia
Facility Name
Institute of Oncology at Prince of Wales Hospital
City
Randwick
State/Province
New South Wales
ZIP/Postal Code
2031
Country
Australia
Facility Name
Royal North Shore Hospital
City
St. Leonards
State/Province
New South Wales
ZIP/Postal Code
2065
Country
Australia
Facility Name
Sydney Cancer Centre at Royal Prince Alfred Hospital
City
Sydney
State/Province
New South Wales
ZIP/Postal Code
2050
Country
Australia
Facility Name
Tamworth Base Hospital
City
Tamworth
State/Province
New South Wales
ZIP/Postal Code
2340
Country
Australia
Facility Name
Manning Base Hospital
City
Taree
State/Province
New South Wales
ZIP/Postal Code
2430
Country
Australia
Facility Name
Newcastle Mater Misericordiae Hospital
City
Waratah
State/Province
New South Wales
ZIP/Postal Code
2298
Country
Australia
Facility Name
Westmead Institute for Cancer Research at Westmead Hospital
City
Wentworthville
State/Province
New South Wales
ZIP/Postal Code
2145
Country
Australia
Facility Name
Royal Brisbane and Women's Hospital
City
Brisbane
State/Province
Queensland
ZIP/Postal Code
4029
Country
Australia
Facility Name
Townsville Hospital
City
Douglas
State/Province
Queensland
ZIP/Postal Code
4814
Country
Australia
Facility Name
Mater Adult Hospital
City
South Brisbane
State/Province
Queensland
ZIP/Postal Code
4101
Country
Australia
Facility Name
Flinders Medical Centre
City
Bedford Park
State/Province
South Australia
ZIP/Postal Code
5042
Country
Australia
Facility Name
Royal Hobart Hospital
City
Hobart
State/Province
Tasmania
ZIP/Postal Code
7000
Country
Australia
Facility Name
Ballarat Oncology and Haematology Services
City
Ballarat
State/Province
Victoria
ZIP/Postal Code
3350
Country
Australia
Facility Name
Box Hill Hospital
City
Box Hill
State/Province
Victoria
ZIP/Postal Code
3128
Country
Australia
Facility Name
Royal Women's Hospital
City
Carlton
State/Province
Victoria
ZIP/Postal Code
3053
Country
Australia
Facility Name
Monash Medical Center - Clayton Campus
City
Clayton
State/Province
Victoria
ZIP/Postal Code
3168
Country
Australia
Facility Name
Frankston Hospital
City
Frankston
State/Province
Victoria
ZIP/Postal Code
3199
Country
Australia
Facility Name
Mercy Hospital for Women
City
Heidelberg
State/Province
Victoria
ZIP/Postal Code
3084
Country
Australia
Facility Name
Murray Valley Private Hospital and Cancer Treatment Centre
City
Wodonga
State/Province
Victoria
ZIP/Postal Code
3690
Country
Australia
Facility Name
Auckland City Hospital
City
Auckland
ZIP/Postal Code
1
Country
New Zealand
Facility Name
Christchurch Hospital
City
Christchurch
ZIP/Postal Code
1
Country
New Zealand
Facility Name
Waikato Hospital
City
Hamilton
ZIP/Postal Code
2020
Country
New Zealand
Facility Name
Wellington Cancer Centre
City
Wellington
ZIP/Postal Code
6039
Country
New Zealand
Facility Name
Furness General Hospital
City
Barrow in Furness
State/Province
England
ZIP/Postal Code
LA14 4LF
Country
United Kingdom
Facility Name
Royal United Hospital
City
Bath
State/Province
England
ZIP/Postal Code
BA1 3NG
Country
United Kingdom
Facility Name
Birmingham Heartlands Hospital
City
Birmingham
State/Province
England
ZIP/Postal Code
B9 5SS
Country
United Kingdom
Facility Name
Royal Blackburn Hospital
City
Blackburn
State/Province
England
ZIP/Postal Code
BB2 3HH
Country
United Kingdom
Facility Name
Blackpool Victoria Hospital
City
Blackpool
State/Province
England
ZIP/Postal Code
FY3 8NR
Country
United Kingdom
Facility Name
Bradford Royal Infirmary
City
Bradford
State/Province
England
ZIP/Postal Code
BD9 6RJ
Country
United Kingdom
Facility Name
Sussex Cancer Centre at Royal Sussex County Hospital
City
Brighton
State/Province
England
ZIP/Postal Code
BN2 5BE
Country
United Kingdom
Facility Name
Bristol Haematology and Oncology Centre
City
Bristol
State/Province
England
ZIP/Postal Code
BS2 8ED
Country
United Kingdom
Facility Name
Broomfield Hospital
City
Broomfield
State/Province
England
ZIP/Postal Code
CM1 7ET
Country
United Kingdom
Facility Name
Queen's Hospital
City
Burton-upon-Trent
State/Province
England
ZIP/Postal Code
DE13 0RB
Country
United Kingdom
Facility Name
Cheltenham General Hospital
City
Cheltenham
State/Province
England
ZIP/Postal Code
GL53 7AN
Country
United Kingdom
Facility Name
Essex County Hospital
City
Colchester
State/Province
England
ZIP/Postal Code
C03 3NB
Country
United Kingdom
Facility Name
Walsgrave Hospital
City
Coventry
State/Province
England
ZIP/Postal Code
CV2 2DX
Country
United Kingdom
Facility Name
Derbyshire Royal Infirmary
City
Derby
State/Province
England
ZIP/Postal Code
DE1 2QY
Country
United Kingdom
Facility Name
Dorset County Hospital
City
Dorchester
State/Province
England
ZIP/Postal Code
DT1 2JY
Country
United Kingdom
Facility Name
Russells Hall Hospital
City
Dudley
State/Province
England
ZIP/Postal Code
DY1 2HQ
Country
United Kingdom
Facility Name
Gloucestershire Royal Hospital
City
Gloucester
State/Province
England
ZIP/Postal Code
GL1 3NN
Country
United Kingdom
Facility Name
Hereford Hospitals NHS Trust
City
Hereford
State/Province
England
ZIP/Postal Code
HR1 2ER
Country
United Kingdom
Facility Name
Huddersfield Royal Infirmary
City
Huddersfield, West Yorks
State/Province
England
ZIP/Postal Code
HD3 3EA
Country
United Kingdom
Facility Name
Ipswich Hospital
City
Ipswich
State/Province
England
ZIP/Postal Code
IP4 5PD
Country
United Kingdom
Facility Name
Airedale General Hospital
City
Keighley
State/Province
England
ZIP/Postal Code
BD20 6TD
Country
United Kingdom
Facility Name
Royal Lancaster Infirmary
City
Lancaster
State/Province
England
ZIP/Postal Code
LA1 4RP
Country
United Kingdom
Facility Name
Leeds Cancer Centre at St. James's University Hospital
City
Leeds
State/Province
England
ZIP/Postal Code
LS9 7TF
Country
United Kingdom
Facility Name
Leicester Royal Infirmary
City
Leicester
State/Province
England
ZIP/Postal Code
LE1 5WW
Country
United Kingdom
Facility Name
Liverpool Women's Hospital
City
Liverpool
State/Province
England
ZIP/Postal Code
LV8 7SS
Country
United Kingdom
Facility Name
Saint Bartholomew's Hospital
City
London
State/Province
England
ZIP/Postal Code
EC1A 7BE
Country
United Kingdom
Facility Name
University College of London Hospitals
City
London
State/Province
England
ZIP/Postal Code
NW1 2PG
Country
United Kingdom
Facility Name
Guy's Hospital
City
London
State/Province
England
ZIP/Postal Code
SE1 9RT
Country
United Kingdom
Facility Name
St. Georges, University of London
City
London
State/Province
England
ZIP/Postal Code
SW17 0QT
Country
United Kingdom
Facility Name
Hammersmith Hospital
City
London
State/Province
England
ZIP/Postal Code
W12 OHS
Country
United Kingdom
Facility Name
Mid Kent Oncology Centre at Maidstone Hospital
City
Maidstone
State/Province
England
ZIP/Postal Code
ME16 9QQ
Country
United Kingdom
Facility Name
Christie Hospital
City
Manchester
State/Province
England
ZIP/Postal Code
M20 4BX
Country
United Kingdom
Facility Name
Queen Elizabeth The Queen Mother Hospital
City
Margate
State/Province
England
ZIP/Postal Code
CT9 4AN
Country
United Kingdom
Facility Name
Clatterbridge Centre for Oncology
City
Merseyside
State/Province
England
ZIP/Postal Code
CH63 4JY
Country
United Kingdom
Facility Name
Northampton General Hospital NHS Trust
City
Northampton
State/Province
England
ZIP/Postal Code
NN1 5BD
Country
United Kingdom
Facility Name
Mount Vernon Cancer Centre at Mount Vernon Hospital
City
Northwood
State/Province
England
ZIP/Postal Code
HA6 2RN
Country
United Kingdom
Facility Name
Kings Mill Hospital
City
Nottinghamshire
State/Province
England
ZIP/Postal Code
NG17 4JL
Country
United Kingdom
Facility Name
Nottingham City Hospital NHS Trust
City
Nottingham
State/Province
England
ZIP/Postal Code
NG5 1PB
Country
United Kingdom
Facility Name
George Eliot Hospital
City
Nuneaton
State/Province
England
ZIP/Postal Code
CV10 7DJ
Country
United Kingdom
Facility Name
Whiston Hospital
City
Prescot Merseyside
State/Province
England
ZIP/Postal Code
L35 5DR
Country
United Kingdom
Facility Name
Rosemere Cancer Centre at Royal Preston Hospital
City
Preston
State/Province
England
ZIP/Postal Code
PR2 9HT
Country
United Kingdom
Facility Name
Alexandra Healthcare NHS
City
Redditch, Worcestershire
State/Province
England
ZIP/Postal Code
B98 7UB
Country
United Kingdom
Facility Name
Cancer Research Centre at Weston Park Hospital
City
Sheffield
State/Province
England
ZIP/Postal Code
S1O 2SJ
Country
United Kingdom
Facility Name
Wexham Park Hospital
City
Slough, Berkshire
State/Province
England
ZIP/Postal Code
SL2 4HL
Country
United Kingdom
Facility Name
Royal Marsden - Surrey
City
Sutton
State/Province
England
ZIP/Postal Code
SM2 5PT
Country
United Kingdom
Facility Name
Taunton and Somerset Hospital
City
Taunton Somerset
State/Province
England
ZIP/Postal Code
TA1 5DA
Country
United Kingdom
Facility Name
South Warwickshire Hospital
City
Warwick, Warwickshire
State/Province
England
ZIP/Postal Code
CV34 5BJ
Country
United Kingdom
Facility Name
Southend University Hospital NHS Foundation Trust
City
Westcliff-On-Sea
State/Province
England
ZIP/Postal Code
SS0 0RY
Country
United Kingdom
Facility Name
Weston General Hospital
City
Weston-super-Mare
State/Province
England
ZIP/Postal Code
BS23 4TQ
Country
United Kingdom
Facility Name
Worcester Royal Hospital
City
Worcester
State/Province
England
ZIP/Postal Code
WR5 1DD
Country
United Kingdom
Facility Name
Worthing Hospital
City
Worthing
State/Province
England
ZIP/Postal Code
BN11 2DH
Country
United Kingdom
Facility Name
Yeovil District Hospital
City
Yeovil - Somerset
State/Province
England
ZIP/Postal Code
BA21 4AT
Country
United Kingdom
Facility Name
Centre for Cancer Research and Cell Biology at Queen's University Belfast
City
Belfast
State/Province
Northern Ireland
ZIP/Postal Code
BT9 7BL
Country
United Kingdom
Facility Name
Aberdeen Royal Infirmary
City
Aberdeen
State/Province
Scotland
ZIP/Postal Code
AB25 2ZN
Country
United Kingdom
Facility Name
Dumfries & Galloway Royal Infirmary
City
Dumfries
State/Province
Scotland
ZIP/Postal Code
DG1 4AP
Country
United Kingdom
Facility Name
Ninewells Hospital
City
Dundee
State/Province
Scotland
ZIP/Postal Code
DD1 9SY
Country
United Kingdom
Facility Name
Edinburgh Cancer Centre at Western General Hospital
City
Edinburgh
State/Province
Scotland
ZIP/Postal Code
EH4 2XR
Country
United Kingdom
Facility Name
Gartnavel General Hospital
City
Glasgow
State/Province
Scotland
ZIP/Postal Code
G12 0YN
Country
United Kingdom
Facility Name
Raigmore Hospital
City
Inverness
State/Province
Scotland
ZIP/Postal Code
1V2 3UJ
Country
United Kingdom
Facility Name
Ysbyty Gwynedd
City
Bangor
State/Province
Wales
ZIP/Postal Code
LL57 2PW
Country
United Kingdom
Facility Name
Velindre Cancer Center at Velindre Hospital
City
Cardiff
State/Province
Wales
ZIP/Postal Code
CF4 7XL
Country
United Kingdom
Facility Name
West Wales General Hospital
City
Carmarthen
State/Province
Wales
ZIP/Postal Code
SA31 2AF
Country
United Kingdom
Facility Name
South West Wales Cancer Institute
City
Swansea
State/Province
Wales
ZIP/Postal Code
SA2 8QA
Country
United Kingdom

12. IPD Sharing Statement

Learn more about this trial

Carboplatin in Treating Patients With Stage IC-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

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