Marijuana Treatment Project - 3 (MTP-3)
Primary Purpose
Marijuana Dependence
Status
Completed
Phase
Not Applicable
Locations
United States
Study Type
Interventional
Intervention
Reinforcement for homework completion
Reinforcement for Abstinence
Case Management
Sponsored by
About this trial
This is an interventional treatment trial for Marijuana Dependence focused on measuring marijuana dependence, self-efficacy, coping skills, attendance, marijuana abstinence
Eligibility Criteria
Inclusion Criteria: Cannabis dependence Willing to accept random assignment to interventions Exclusion Criteria: Current dependence on alcohol or other drugs Problems that require inpatient hospitalization Reading ability below fifth grade level Lack of reliable transportation to treatment Excessive commuting distance
Sites / Locations
- University of Connecticut Health Center
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm Type
Experimental
Active Comparator
Active Comparator
Arm Label
Reinforcement for homework completion
Reinforcement for Abstinence
Case Management
Arm Description
Outcomes
Primary Outcome Measures
Marijuana abstinence
Self-efficacy, use of coping skills, and treatment attendance
Secondary Outcome Measures
Continuous abstinence will be predicted by (a) treatment attendance; (b) posttreatment self-efficacy for coping; and (c) use of coping skills
Full Information
NCT ID
NCT00107588
First Posted
April 5, 2005
Last Updated
July 27, 2017
Sponsor
UConn Health
Collaborators
National Institute on Drug Abuse (NIDA)
1. Study Identification
Unique Protocol Identification Number
NCT00107588
Brief Title
Marijuana Treatment Project - 3
Acronym
MTP-3
Official Title
Contingency Management for Marijuana Dependence
Study Type
Interventional
2. Study Status
Record Verification Date
July 2017
Overall Recruitment Status
Completed
Study Start Date
February 2007 (undefined)
Primary Completion Date
April 2011 (Actual)
Study Completion Date
August 2012 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
UConn Health
Collaborators
National Institute on Drug Abuse (NIDA)
4. Oversight
Data Monitoring Committee
Yes
5. Study Description
Brief Summary
The goal of this research is to improve treatment outcome for marijuana-dependent individuals. The current study builds on the findings of our prior NIDA-funded marijuana treatment study in which improved client outcomes were associated with greater treatment attendance, greater client self-efficacy, and greater use of coping skills. We will use a contingency management paradigm to provide tangible reinforcement for completing homework assignments that are designed to enhance coping skills. It is anticipated that this will result in greater homework compliance, leading to greater self-efficacy regarding one's ability to cope with high-risk situations. Improved self-efficacy will enhance the likelihood of employing coping skills in high-risk situations, thereby increasing the probability of achieving and maintaining abstinence.
Detailed Description
Participants will receive an intervention combining one session of motivational enhancement therapy with eight sessions of cognitive-behavioral coping skills therapy (MET+CBT). A contingency management procedure will be added to this intervention, providing reinforcement for completion of homework, as verified by call-ins to an Interactive Voice Recording (IVR) system. Outcomes will be compared to an MET+CBT intervention in which reinforcement will be provided for marijuana-free urine specimens, and to a control group that receives Case Management. Recruitment of 234 marijuana-dependent participants will occur over a three-year period. They will be randomly assigned to one of the three 9-session interventions. Treatment will be individual, manualized, and provided on an outpatient basis. Pretreatment assessments will obtain baseline data; follow-up assessments at three-month intervals for one year will evaluate marijuana use outcomes, other drug or alcohol use, and psychosocial functioning. It is anticipated that the intervention in which completion of homework is reinforced will result in the best outcomes. The mechanisms by which the interventions result in behavior change will be the specific focus of attention in this study.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Marijuana Dependence
Keywords
marijuana dependence, self-efficacy, coping skills, attendance, marijuana abstinence
7. Study Design
Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
Randomized
Enrollment
215 (Actual)
8. Arms, Groups, and Interventions
Arm Title
Reinforcement for homework completion
Arm Type
Experimental
Arm Title
Reinforcement for Abstinence
Arm Type
Active Comparator
Arm Title
Case Management
Arm Type
Active Comparator
Intervention Type
Behavioral
Intervention Name(s)
Reinforcement for homework completion
Intervention Description
Provides contingent reinforcement for engaging in homework activities designed to enhance coping skills
Intervention Type
Behavioral
Intervention Name(s)
Reinforcement for Abstinence
Intervention Description
Provides contingent reinforcement for submitting marijuana-free urine specimen
Intervention Type
Behavioral
Intervention Name(s)
Case Management
Intervention Description
Will control for the effect of therapist-client contact by providing supportive case management as an active control condition.
Primary Outcome Measure Information:
Title
Marijuana abstinence
Time Frame
One-year follow-up period
Title
Self-efficacy, use of coping skills, and treatment attendance
Time Frame
During 2-month treatment period
Secondary Outcome Measure Information:
Title
Continuous abstinence will be predicted by (a) treatment attendance; (b) posttreatment self-efficacy for coping; and (c) use of coping skills
Time Frame
One-year follow-up period
10. Eligibility
Sex
All
Minimum Age & Unit of Time
18 Years
Maximum Age & Unit of Time
80 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
Cannabis dependence
Willing to accept random assignment to interventions
Exclusion Criteria:
Current dependence on alcohol or other drugs
Problems that require inpatient hospitalization
Reading ability below fifth grade level
Lack of reliable transportation to treatment
Excessive commuting distance
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Mark D Litt, Ph.D.
Organizational Affiliation
UConn Health
Official's Role
Principal Investigator
Facility Information:
Facility Name
University of Connecticut Health Center
City
Farmington
State/Province
Connecticut
ZIP/Postal Code
06030-3910
Country
United States
12. IPD Sharing Statement
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