Androgen Deprivation Therapy in Treating Patients With Prostate Cancer
Prostate Cancer
About this trial
This is an interventional treatment trial for Prostate Cancer focused on measuring adenocarcinoma of the prostate, stage I prostate cancer, stage IIB prostate cancer, stage IIA prostate cancer, stage III prostate cancer, stage IV prostate cancer, recurrent prostate cancer
Eligibility Criteria
DISEASE CHARACTERISTICS: Histologically confirmed adenocarcinoma of the prostate Prostate-specific antigen (PSA) relapse OR incurable disease diagnosed within the past 2 months AND meets criteria for either of the following groups: Group 1 In PSA relapse after definitive radical treatment (prostatectomy or radiotherapy), as evidenced by 1 the following: Post-prostatectomy PSA level ≥ 0.2 ng/mL At least 3 rising PSA levels (post-radiotherapy) obtained ≥ 1 month apart, with the last PSA obtained within the past 2 months No metastatic disease by bone scan or abdomino-pelvic CT scan Group 2 Not suitable for radical treatment at primary diagnosis Not planning to receive curative treatment Localized or metastatic disease No symptomatic disease requiring radiotherapy or immediate hormonal therapy No symptomatic disease requiring therapy PATIENT CHARACTERISTICS: Age Any age Performance status Not specified Life expectancy At least 5 years Hematopoietic Not specified Hepatic Not specified Renal Not specified Other No other significant comorbid condition that would limit life expectancy to < 5 years PRIOR CONCURRENT THERAPY: Biologic therapy Not specified Chemotherapy Not specified Endocrine therapy At least 12 months since prior androgen deprivation therapy (ADT) administered in the neoadjuvant or concurrent (with radiotherapy) setting (group 1) No prior ADT (group 2) Radiotherapy See Disease Characteristics See Endocrine therapy Surgery See Disease Characteristics Other No concurrent enrollment in TROG-96.01 or TROG-RADAR protocols
Sites / Locations
- Cancer Therapy Centre at Campbelltown HospitalRecruiting
- Concord Repatriation General HospitalRecruiting
- Nepean Cancer Care Centre at Nepean HospitalRecruiting
- Cancer Therapy Centre at Liverpool HospitalRecruiting
- Sydney Cancer Centre at Royal Prince Alfred HospitalRecruiting
- Westmead Institute for Cancer Research at Westmead HospitalRecruiting
- Royal Brisbane and Women's HospitalRecruiting
- Princess Alexandra HospitalRecruiting
- Mater Adult HospitalRecruiting
- East Coast Cancer CentreRecruiting
- Urological SolutionsRecruiting
- Repatriation General HospitalRecruiting
- Peter MacCallum Cancer CentreRecruiting
- Geelong HospitalRecruiting
- Alfred HospitalRecruiting
- West Gippsland HospitalRecruiting
- Christchurch HospitalRecruiting
- Dunedin HospitalRecruiting
- Waikato HospitalRecruiting
- Palmerston North HospitalRecruiting