Antibiotic Efficacy in Third Molar Surgery
Alveolar Osteitis, Dry Socket, Infection
About this trial
This is an interventional treatment trial for Alveolar Osteitis focused on measuring Dry socket, Third molar, Infection, postop-infection, Antibiotic efficacy, Infection characterized by pus,erythema,edema and pain
Eligibility Criteria
Inclusion Criteria: Demographics: While all ages are eligible for study enrollment, as a practical matter, most patients having M3s removed are usually > 13-14 years of age. Gender: Males and females will be offered to participate in this study. Race: All races and ethnicities are eligible for study enrollment. Clinical status: at least one impacted mandibular third molar ( M3 ) must be scheduled for extraction. Anesthesia: Patient request that the procedure be executed using intravenous sedation or general anesthesia. Intravenous sedation will be accomplished with use of an IV placed in the antecubital fossa of each patient Health status: Healthy patients or patients with mild systemic disease, i.e. ASA status < 3, are eligible for study enrollment. Exclusion Criteria: Pre-existing infection: Infection is characterised as having an area with frank purulence and/or cellulitis characterized by erythema, induration and inability to open the mouth wide enough to provide access to the airway. Pre-existing Systemic Illness: as evidenced by severe dry mouth, patients who have undergone radiotherapy for oral cancer, patients that are immunocompromised, patients that require antibiotic prophylaxis for endocarditis, as well as, patients who are taking antimicrobials for other systemic diseases, i.e., uncontrolled diabetes., ASA status > 2. Allergic Reactions to Medications: Patients who are allergic to Penicillin and Clindamycin will be excluded from the study. Anesthesia: Patient request that the operation be performed with local anesthesia without intravenous sedation or general anesthesia. Pregnancy: Pregnancy is a relative contraindication for study enrollment. If after consultation with the obstetrician, there is no contraindication to removing the impacted teeth with sedation or contraindication to receiving the test medications (penicillin or clindamycin) and the patient wants to pursue treatment, she would be considered eligible for study enrollment.
Sites / Locations
- Outpatient Clinic for Oral and Maxillofacial Surgery, Wang Pavilion, ACC230