MEDICLAS Study (Metabolic Effects of Different Classes of AntiretroviralS)
HIV Infections, HIV-Associated Lipodystrophy Syndrome
About this trial
This is an interventional prevention trial for HIV Infections focused on measuring HIV, HIV-associated lipodystrophy syndrome
Eligibility Criteria
Inclusion Criteria: Male Age between 18 and 70 years. No prior use of antiretroviral therapy Indication for antiretroviral treatment according to common standards Exclusion Criteria: Female sex Body mass index (kg/m2) > 35. Known history of diabetes mellitus or hyperlipidemia Use of coenzyme A reductase inhibitor or fibric acid derivative in the last 6 weeks before inclusion Use of the following medication: systemic corticosteroids, thiazide diuretics, calcium-entry blockers, angiotensin-converting inhibitors, nitrates Use of nandrolone or testosterone Any disorder or condition which can be expected to lead to lessened compliance with the study protocol.
Sites / Locations
- Helsinki University Central Hospital
- Academic Medical Center
- Medisch Centrum Jan van Goyen
- Onze Lieve Vrouwe Gasthuis, location Oosterpark
- Onze Lieve Vrouwe Gasthuis, location Prinsengracht
- Slotervaart ziekenhuis
- VUMC Free University Medical Center
- Ziekenhuis Leyenburg
- Kennemer Gasthuis, location Elisabeth
- Leids Universitair Medisch Centrum
- Erasmus Universitair Medisch Centrum
- Hospital Clinic
- Royal Free Hospital