Positioning and Tracking the Prostate During External Beam Radiation
Prostate Cancer
About this trial
This is an interventional treatment trial for Prostate Cancer focused on measuring Prostate, Cancer, Radiotherapy, Neoplasm, Localization, Tracking, Cancer of Prostate, Neoplasms, Prostate
Eligibility Criteria
Inclusion Criteria: 18 years of age or older Histologically confirmed diagnosis of prostate cancer Intact prostate (minor transurethral resection of the prostate [TURP] defects are allowed at the discretion of the investigator) Ability to comply with study visit schedule Exclusion Criteria: Prior treatment for prostate cancer. Prostate cancer stage IV (metastatic disease). Patients who are not eligible for prostate biopsy. Past history of abdominoperineal (A-P) resection. Planned course of treatment using brachytherapy (permanent brachytherapy seeds or high dose rate [HDR] brachytherapy). Allergy to local anesthetics. Patients with any permanently implanted medical devices that have an energy source, such as pacemakers, defibrillators, neurostimulators, and drug infusion pumps; this also includes prosthetic implants in the abdomen or pelvis, such as an artificial hip; or vascular implants such as arterial stents or stent-grafts for aortic aneurysms. This does not include surgical clips, staples or coronary stents. History of chronic prostatitis. Patients with a history of recent acute and/or chronic bleeding disorders. Patients on therapeutic anti-coagulants or anti-platelet therapy, not including aspirin. Patients for which the maximum anterior-posterior separation through the torso minus the height of the center of the prostate is greater than 23 cm. (Measurements will be made visually with a ruler.) Baseline evaluation shows an INR or PTT outside of the normal range for the institution; platelet count < 75,000 mm3; or creatinine > 2.0 mg/dl. Any other medical condition or laboratory value that would, at the discretion of the investigator, preclude the patient from participation in a clinical trial
Sites / Locations
- Scottsdale Healthcare - Osborn
- Sharp Memorial Hospital
- M.D. Anderson Cancer Center Orlando
- The Nebraska Medical Center
- The Cleveland Clinic
Arms of the Study
Arm 1
Experimental
Single Group Assignment
Calypso® 4D Localization System