STARS Breast Trial (Study of Anastrozole and Radiotherapy Sequencing Pilot)
Breast Cancer
About this trial
This is an interventional treatment trial for Breast Cancer focused on measuring Breast Cancer, Timing of Radiotherapy, Local Control
Eligibility Criteria
Inclusion Criteria: Age 18 or more years. No upper limit. Post total mastectomy or lumpectomy. All planned surgery complete. Margins clear (no tumour contacting the inked margin) Tumour oestrogen or progesterone receptor positive Planned dose to irradiated volumes at least the biological equivalent of 45 Gy in 25 fractions or more. ECOG 0-2 Patients post menopausal using same criteria as ATAC study. Written informed consent Exclusion Criteria: Previous radiotherapy to the area to be treated. Previous invasive malignancy within 5 years of current breast cancer diagnosis with the exception of cervix in-situ or skin cancer other than melanoma. Patients with clinical evidence of metastatic disease. Previous hormonal breast therapy. Ongoing hormone replacement therapy.
Sites / Locations
- Liverpool Hospital
- St George HospitalRecruiting
- Campbelltown Hospital
- Princess Alexandra Hospital