Study of Colchicine to Treat Acute Pericarditis and Prevent Recurrences
Pericarditis
About this trial
This is an interventional treatment trial for Pericarditis focused on measuring Pericarditis, Recurrence, Therapeutics, Prevention, Colchicine
Eligibility Criteria
Inclusion Criteria: Patients with acute pericarditis (index attack) Age≥ 18 years Informed consent Exclusion Criteria: Suspected neoplastic, tuberculous, or purulent etiology Known severe liver disease and/or elevated transaminases >1.5 times the upper limit of normality Serum creatinine >2.5 mg/dl Serum creatine kinase (CK) over the upper limit of normality or known myopathy Known gastrointestinal or blood disease Pregnant or lactating women or women not protected by a contraception method Known hypersensibility to colchicine Treatment with colchicine at enrolment
Sites / Locations
- Cardiology Department. Maria Vittoria Hospital, ASL 3 Torino
- Internal Medicine Division
- Cardiology Department-Ospedale Regionale
- Ospedale di Rivoli
Arms of the Study
Arm 1
Arm 2
Placebo Comparator
Active Comparator
Placebo
Colchicine
Conventional therapy plus placebo
Conventional therapy plus colchicine