Nitroprusside for Prevention of no-Reflow in Primary Angioplasty
Myocardial Infarction
About this trial
This is an interventional prevention trial for Myocardial Infarction focused on measuring myocardial infarction, angioplasty, nitric oxide, prevention, acute myocardial infarction
Eligibility Criteria
Inclusion Criteria: Acute ST elevation myocardial infarction (MI) patients planned for primary PCI Diagnostic angiography demonstrating a TIMI flow grade <3 in the coronary artery before the PCI Exclusion Criteria: An admission electrocardiogram (ECG) showing complete left bundle branch block or a paced rhythm Systolic blood pressure < 90 mmHg A history of coronary bypass operation A known allergic reaction to nitroprusside Chronic hemodialysis Intravenous drug abuse Pregnancy Rescue intervention after failed thrombolysis Contraindications to aspirin or clopidogrel Need for emergent coronary artery bypass surgery Inability to provide informed consent
Sites / Locations
- Soroka University Medical Center