Ultraviolet B (UVB) Light Therapy in the Treatment of Skin Conditions With Altered Dermal Matrix
Keloid, Scleroderma, Localized, Acne Keloidalis
About this trial
This is an interventional prevention trial for Keloid focused on measuring UVB, keloid, scleroderma, acne keloidalis nuchae, scars, granuloma annulare
Eligibility Criteria
Inclusion Criteria: In good general health and between 10-80 years of age. Willing and able to receive UVB, as directed in the protocol; make evaluation visits; follow protocol restrictions; and sign a written, witnessed, informed consent form. Have a clinical diagnosis of keloid, scleroderma, old burn scars, granuloma annulare, or acne keloidalis nuchae. No disease states or physical conditions that would impair evaluation of the test site Must live within a reasonable driving distance of Ann Arbor, Michigan, and/or be able to attend all of the scheduled appointments during the study. Exclusion Criteria: Have a history of photosensitivity (development of hives or bumps with exposure to light) or experience hypersensitivity in a UVB photo-provocation test. Have participated in another investigational study in the past 4 weeks, taken oral therapy for skin condition, or on photosensitizing medications. Pregnant, nursing, or planning to become pregnant during the study.
Sites / Locations
- University of Michigan Department of Dermatology
Arms of the Study
Arm 1
Experimental
UVB Irradiation
A dose of up to 320 mJ/cm2 from a UVB irradiation device will be administered at maximum 5 times per week for 16 weeks.