Concomitant Use and Staggered Use of Vaccine and Oral Poliovirus (OPV) in Healthy Infants (V260-014)(COMPLETED)
Rotavirus Infections, Gastroenteritis
About this trial
This is an interventional treatment trial for Rotavirus Infections
Eligibility Criteria
Inclusion Criteria: Infants in good health Exclusion Criteria: Previous administration of any oral poliovirus vaccine (OPV) and rotavirus vaccine Receipt of inactivated poliovirus vaccine (IPV) prior to the first dose of either study vaccine, or at any time during the course of the study Any condition resulting in depressed immunity Any allergy to any vaccine component as stated in the package circulars Allergies to polymyxin B, neomycin or any other antibiotics Receipt of intramuscular, oral, or intravenous corticosteroid treatment History of congenital abdominal disorders, intussusception, or abdominal surgery; clinical evidence of active gastrointestinal illness History of known prior rotavirus gastroenteritis, chronic diarrhea, or failure to thrive Prior receipt of a blood transfusion or blood products, including immunoglobulin Fever, with a rectal temperature of ≥38.1°C (≥ 100.5°F) at the time of immunization Infants residing in a household with an immunocompromised person
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
1
2
RotaTeq and OPV concomitantly
RotaTeq and OPV on staggered schedule